Biomedical subjects

James Everett

Publications and source records attributed to James Everett.

3 recordsLinked to original sources

PubMed2003

Fine motor dexterity is correlated to social functioning in schizophrenia.

OBJECTIVE: To identify neuropsychological domains, including fine motor dexterity, that are related to social functioning in schizophrenia. METHOD: Thirty-six DSM-IV schizophrenic subjects were assessed using the Purdue Pegboard test, the Modified Wisconsin Card Sorting test, the Tower of London, Schwartz' Reaction Time and Wechsler's Associate Learning and Digit Span tests. Social functioning was measured by the Social and Occupational Functional Assessment Scale. RESULTS: Univariate regression analyses showed that the Purdue Pegboard, the Modified Card Sorting test, the Tower of London and Wechsler's Associate Learning subtest were significantly linked to social functioning. The best fitting multivariate model to explain social functioning included fine motor dexterity and executive functioning. CONCLUSION: Various neuropsychological measures correlated to social functioning, the correlation involving fine motor dexterity being the strongest one. Future studies of the prediction of social functioning in schizophrenia should include fine motor dexterity.

Cognition Disorders↗

PubMed2003

A pilot neuropsychological study of Kraepelinian and non-Kraepelinian schizophrenia.

OBJECTIVE: This is the first study to report a direct comparison of neuropsychological performance in Kraepelinian vs. non-Kraepelinian schizophrenia (SZ). METHODS: 17 Kraepelinian and 19 non-Kraepelinian subjects were assessed on a neuropsychological battery including the Purdue Pegboard, Schwartz' Reaction Time task, the Modified Card Sorting Test, the Wechsler's Associate Learning Test and the Digit Span. RESULTS: Kraepelinian schizophrenia was characterized by more impaired performance on the Purdue Pegboard and the Card Sorting test. These differences remained significant when introducing, as covariates, the type of neuroleptic used, the use of anticholinergic medication, age and gender. Differences on the Reaction Time, the Associate Learning and the Digit Span tasks did not reach statistical significance. CONCLUSIONS: These results suggest that Kraepelinian schizophrenia is characterized by impaired performance on fine motor dexterity and executive functioning. These results further add to the evidence for the validity of the distinction between Kraepelinian and non-Kraepelinian schizophrenia as a strategy to better understand the factors influencing severity and/or outcome in schizophrenia.

Adult↗

PubMed2003

Depression, attention, and time estimation.

Depression is known to affect several cognitive functions, but little is known about the effect of this neuropsychological disorder on timing tasks. In the present experiment, 15 depressed and 20 non-depressed participants, classified on the basis of the Beck Depression Inventory, were tested on attentional and on temporal processing tasks. On the Continuous Performance Test, depressed participants made more omissions, but not more erroneous responses, than non-depressed participants. As well, discrimination of relatively long intervals (1120 vs 1280 ms) was poorer for the depressed group, which was not the case for discrimination of brief durations (80 vs 120 ms, and 450 vs 550 ms). Finally, there was a significant difference between groups regarding the variability of 1- or 10-s interval productions made with continuous series of finger taps. The attentional requirements of long-interval processing seems to be a critical factor in depression-induced deficits of temporal processing.

Adult↗