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Biomedical subjects

Jamie N Bakkum

Publications and source records attributed to Jamie N Bakkum.

3 recordsLinked to original sources

In utero losartan withdrawal and subsequent development of fetal inferior vena cava thrombosis.

BACKGROUND: Angiotensin receptor blockers are antihypertensive medications prescribed by a wide variety of physicians, especially for patients with coexistent diabetes mellitus. Angiotensin receptor blockers, as well as angiotensin-converting enzyme inhibitors, are contraindicated in pregnancy. CASE: We describe the reversal of losartan-induced oligohydramnios at 27 weeks of gestation with subsequent development of fetal thrombosis and possible mechanism of action for this extremely rare in utero complication. CONCLUSION: This theory may help explain the fetal stillbirths in women taking this class of medications during the second and third trimester of pregnancy.

Angiotensin II Type 1 Receptor Blockers↗

A complex ovarian cyst.

BACKGROUND: Acute pelvic pain in women is a common diagnostic dilemma encountered by the gynecologist. We describe a case of acute pelvic pain with an unusual etiology. CASE: A 40-year-old multipara presented within hours of the onset of acute pelvic pain. She was treated conservatively with analgesics after computed tomography of the abdomen and pelvis revealed a ruptured ovarian cyst. Upon return to the emergency room, she was admitted to a gynecologic service for pain control. The etiology of her acute pelvic pain eventually declared itself. CONCLUSION: The differential diagnosis of acute pelvic pain represents a variety of organ systems.

Adult↗

Prenatal diagnosis of cri du chat syndrome with encephalocele.

A 19-year-old primigravida was found to have an encephalocele on screening ultrasound study. Amniocentesis indicated cri du chat syndrome, 5p-. Although cri du chat syndrome has been noted in association with central nervous system malformations, encephalocele is a rare finding in this syndrome.

Adult↗