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Biomedical subjects

Jamshed Akhtar

Publications and source records attributed to Jamshed Akhtar.

8 recordsLinked to original sources

Congenital pyloric atresia: isolated and associated with aplasia cutis congenita.

Two cases of congenital pyloric atresia (CPA) are, hereby, reported. One was suspected on antenatal ultrasound and turned out to be an isolated anomaly. Other patient had a rare association of aplasia cutis congenita with congenital pyloric atresia. The lesions of aplasia cutis congenita were multiple while congenital pyloric atresia was of type II. The patient with an isolated lesion survived following surgery while the other baby died of sepsis in postoperative period.

Adult↗

Sirenomelia (Mermaid baby).

Sirenomelia is a rare anomaly that rarely occurs as an isolated lesion. Several theories have been proposed regarding the etiopathogenesis. In this communication, we report a case of sirenomelia. Our patient was referred to hospital at the age of four hours. On examination, fusion of both lower limbs with hook shaped appendage, attached distally, absent genitalia and absent anal orifice was found. Spine was deficient in sacral region. Upper torso looked normal. Baby also had frothing from mouth. Abdomen was non-distended. Feeding tube no.10 was tried to pass through mouth, which got obstructed at the level of upper esophagus that suggested oesophageal atresia. The skeletogram revealed absence of pelvic bones, sacral agenesis, absent fibulae and fracture of both femora. The patient died at the age of 12 hours.

Abnormalities, Multiple↗

Crimean-Congo haemorrhagic fever: An alert for health care workers.

Recently we have come across sudden increase in cases of haemorrhagic fever. This has led to lot of speculations especially with regard to its spread. Crimean-Congo haemorrhagic fever is one condition about which awareness among health care workers is important. This is discussed in this article.

Hemorrhagic Fever, Crimean↗

Non-operative management of intestinal obstruction due to ascaris lumbricoides.

OBJECTIVE: To compare, evaluate and analyze three different non-operative modalities of treatment of intestinal obstruction due to ascaris lumbricoides. DESIGN: A non-randomized, cohort and comparative study. PLACE AND DURATION OF STUDY: Department of Pediatric Surgery, National Institute of Child Health, Karachi from March 2001 to October 2002. PATIENTS AND METHODS: A total of 45 patients with the diagnosis of intestinal obstruction due to ascaris lumbricoides were included in the study. They were divided in 3 groups of 15 patients each. Group I patients were given I/V fluids only, group II patients were given hyoscinbutylbromide in infusion and group III patients were given hypertonic saline enema. The outcome of all groups was compared in terms of improvement in obstruction and hospital stay. The data was analyzed by SPSS 11.0 by using ANOVA and HSD Tuckey test for multiple comparisons. RESULTS: The non-operative treatment was successful in all of the patients. In group III improvement of intestinal obstruction occurred in 1.6 +/- 1.11 days (p value=0.001), whereas it was 2.6 +/-1.11 days in group II and 3.4 +/-1.35 days in group I. The mean hospital stay in group III was 4 +/-1.69 days (p value=0.003), whereas it was 6.27 +/- 2.31 days in group II and 5.87 +/-1.25 days in group I. CONCLUSION: We recommend that hypertonic saline enema is a better non-operative treatment modality of intestinal obstruction, due to ascaris lumbricoides, in patients who do not have peritonitis. It is associated with early improvement of obstruction coupled with reduced hospital stay.

Analysis of Variance↗