[This is the truth].
Explore the source record for details and available documents.
Biological Products↗
Biomedical subjects
Jan Holt
Publications and source records attributed to Jan Holt.
Cumulative incidence of asthma and allergy in north-Norwegian schoolchildren in 1985 and 1995.
The prevalence of asthma and allergy in children is increasing. In order to investigate time trends, follow-up studies conducted several years apart and with identical study designs are essential. We compared two identical, cross-sectional and questionnaire-based studies of asthma and allergy in north-Norwegian schoolchildren (7-13 years of age). The first study was conducted in 1985 (n = 10,093) and the second in 1995 (n = 8,676). The cumulative incidence was as follows: diagnosed asthma, 8.6% in 1995 vs. 5.1% in 1985, relative risk (RR) = 1.71 (95% CI: 1.53-1.90); allergic rhinoconjunctivitis, 22.1% in 1995 vs. 16.4% in 1985, RR = 1.39 (95% CI: 1.31-1.47); and atopic dermatitis, 19.7% in 1995 vs. 13.2% in 1985, RR = 1.48 (95% CI: 1.39-1.58). The cumulative incidence of allergic rhinoconjunctivitis and atopic dermatitis was higher in children of Sami ethnicity than Norse ethnicity in the 1985 study. Furthermore, although not statistically significant, there was a trend towards a greater increase in the cumulative incidence of diagnosed asthma, symptoms of asthma, allergic rhinoconjunctivitis, and atopic dermatitis from 1985 to 1995 in children of Sami ethnicity than Norse ethnicity. We conclude that there has been a marked increase in the cumulative incidence of asthma and allergy prevalence among schoolchildren in northern Norway from 1985 to 1995.
Adolescent↗
Audit of neonatal deaths of nonmalformed infants of 34 or more weeks' gestation: unavoidable catastrophic events or suboptimal care?
BACKGROUND: The neonatal death rate (death < or = 28 days/1000 live births) has decreased and the level is now so low that it has been questioned whether further improvement is possible. The aim of this study was to categorize nonmalformed infants of 34 weeks' or more gestational age dying in the neonatal period to analyze if these deaths might have been prevented. MATERIAL AND METHODS: We used the audit method to study neonatal deaths during 1986-98 in a county population of approximately 240 000 inhabitants. RESULTS: Twenty-six neonatal deaths from a population of 41 901 live births were analyzed. The neonatal deaths were found to be associated with antepartum hypoxia (six cases); intrapartum catastrophes (seven cases); intrapartum monitoring deficiencies (five cases); resuscitation and stabilization after birth (two cases); infection (one case); sudden infant death syndrome (four cases); and peritonitis (died at home, one case). Suboptimal care was recorded in 16 cases. Neonatal death was unlikely to be associated with suboptimal care in six cases, but in 10 cases suboptimal care might or was likely to have brought about the fatal outcome. CONCLUSION: Avoiding suboptimal care might or is likely to prevent neonatal death in 10/26 (38.5%) of nonmalformed infants of 34 weeks' or more gestational age. Such improvements may, however, only slightly influence the neonatal death rate, with a reduction from 4.4 to 4.2/1000 live births.
Age Factors↗