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Jane-Ming Lin

Publications and source records attributed to Jane-Ming Lin.

16 recordsLinked to original sources
PubMed2006

Stratus optical coherence tomography for evaluating optic disc pits associated with maculopathy before and after vitrectomy: two case reports.

Optic disc pit (ODP) can be either congenital or acquired. Congenital ODP is typically unilateral, and the visual acuity and visual field are normal unless associated with macular serous detachment, which occurs in about 25-75% of cases. Acquired ODP is known as an important risk factor for progressive visual field loss in glaucoma. The fundus finding of congenital ODP includes oval depression involving the optic disc, with or without macular serous detachment. We used third-generation Stratus optical coherence tomography (Straus OCT) to investigate the possible pathogenesis of ODP associated with maculopathy and to monitor the anatomic changes before and after treatment.

Adolescent↗
PubMed2005

Noninfectious hypopion after intravitreal triamcinolone acetonide injection for central retinal vein occlusion: a case report.

Although it is rare, infectious endophthalmitis is a severe ocular complication resulting from intravitreal injection of triamcinolone acetonide (TA). Therefore, care must be taken by ophthalmologists to differentiate between what is infectious and noninfectious endophthalmitis. We report on a 62-year-old woman who received an intravitreal injection of TA for treatment of central retinal vein occlusion. One day after the injection, a hypopion (a white-yellowish deposit) was noted in the inferior anterior chamber. The patient complained that her vision had deteriorated, but there was no pain, eyelid edema, increased conjunctival injection or corneal edema. The hypopion gradually diminished and by the fifth postoperative day, resolved completely without the administration of intravitreal or systemic antibiotic therapy.

Anti-Bacterial Agents↗
PubMed2005

Effects of laser in situ keratomileusis on the corneal endothelium.

The purpose of this study was to assess the effects of laser in situ keratomileusis (LASIK) on the corneal endothelium. In a prospective study, the corneal endothelium of 87 eyes (45 patients) was examined before and 1 month after LASIK. Patients were divided into two groups: people who wear contact lenses (48 eyes) and people who had never worn contact lenses (39 eyes). The corneal endothelium was analyzed for cell density, percentage of hexagonal cells, and coefficient of variation (CV) of cell size. The mean cell density and percentage of hexagonal cells was significantly higher 1 month after LASIK for all 87 eyes. However, the mean CV of cell size was not significantly different. In contact lens wearers, there was a significant increase in mean cell density and percentage of hexagonal cells, but there was no significant change in mean CV of cell size after LASIK. Among patients who had never worn contact lenses, no significant changes were noted in mean cell density, percentage of hexagonal cells, or mean CV of cell size. In this study, LASIK caused no damage to the corneal endothelium. Postoperative improvements in the mean cell density and percentage of hexagonal cells in patients who were contact lens wearers may be related to the discontinuance of contact lens use after LASIK.

Adolescent↗
PubMed2005

The fixed combination of fortified vancomycin and amikacin ophthalmic solution--VA solution: in vitro study of the potency and stability.

PURPOSE: We compared the in vitro potency and stability of a fixed combination of vancomycin and amikacin solution (VA solution) with amikacin or vancomycin solution. METHODS: Solutions of 2% amikacin (20 mg/mL) and of 5% vancomycin (50 mg/mL) and VA solution (each 1 mL contained 20 mg of amikacin and 50 mg of vancomycin) were prepared from parenteral antibiotics by reconstituting them with sterile injection water and refrigerated (4 degrees C) in the dark. Triplicate 5-mL portions of each solution were tested before storage and 7 and 14 days after preparation for potency of antimicrobial activity by the disk diffusion method and for stability. RESULTS: There were no significant differences in the diameter of zones of inhibition of VA solution compared with amikacin or vancomycin solution within a 2-week period. Visual inspection revealed that all solutions remained clear, colorless, and particle-free at 4 degrees C throughout the study period. For osmolarity, the VA solution was much higher than that of either amikacin or vancomycin solution at all tested times and more near the well-tolerated range of human eyes. There were no significant differences at days 0, 7, or 14 for either vancomycin, amikacin, or VA solution. For pH, the VA solution was higher than that of vancomycin solution (nearly equal to that of amikacin solution) at each time and more near the level of normal tear film. The pH did not differ significantly for either vancomycin, amikacin, or VA solution at all tested times. CONCLUSIONS: The vancomycin and amikacin ophthalmic solutions can be mixed together with the same potency and stable physical properties. It may be useful in the treatment of bacterial keratitis pending clinical trials to determine its effectiveness and safety.

Amikacin↗
PubMed2005

Laser in situ keratomileusis for different degrees of myopia.

PURPOSE: To determine the efficacy, predictability, stability and safety of laser in situ keratomileusis (LASIK) in treating patients with different degrees of myopia. METHODS: We enrolled 386 eyes of 200 consecutive patients who underwent LASIK and divided them into four groups according to their degree of preoperative spherical equivalent (SE). Group 1 eyes ranged between - 1.00 and - 3.99 dioptres (D) (low myopia). Group 2 eyes ranged between - 4.00 and - 5.99 D (moderate myopia). Group 3 eyes ranged between - 6.00 and - 9.99 D (high myopia). Group 4 eyes were over - 9.99 D (extreme myopia). Follow-up was at 1 day, 1 week and 1, 3, 6, 12 and 18 months postoperatively. RESULTS: Our study included 386 eyes of 200 patients with SE ranging from - 3.00 to - 16.00 D (mean - 7.14 +/- 2.87 D). All eyes were seen at 1 day postoperatively. A total of 360 eyes (93%) were examined at 1 week, 330 eyes (85%) at 1 month, 281 eyes (73%) at 3 months, 247 eyes (64%) at 6 months, 199 eyes (52%) at 12 months and 142 eyes (37%) at 18 months. The postoperative data from 1 day to 12 months were used because of the low follow-up rate at 18 months postoperatively. Group 1 consisted of 30 eyes. The mean SE was - 3.52 +/- 0.43 D preoperatively and - 0.40 +/- 0.58 D at 1 month, - 0.46 +/- 0.60 D at 6 months and - 0.42 +/- 0.50 D at 12 months postoperatively. Uncorrected visual acuity (UCVA) was 20/40 or better in 95% of eyes at 1 day and in 100% of eyes at 6 and 12 months postoperatively. Group 2 consisted of 151 eyes. The mean SE was - 5.36 +/- 0.67 D preoperatively and - 0.54 +/- 0.78 D at 1 month, - 0.56 +/- 0.90 D at 6 months and - 0.55 +/- 0.82 D at 12 months postoperatively. Uncorrected VA was 20/40 or better in 95% of eyes at 1 day and in 100% of eyes at 6 and 12 months postoperatively. Group 3 consisted of 167 eyes. The mean SE was - 8.15 +/- 0.94 D preoperatively and - 0.58 +/- 0.90 D at 1 month, - 0.67 +/- 1.00 D at 6 months and - 0.64 +/- 0.95 D at 12 months postoperatively. Uncorrected VA was 20/40 or better in 90% of eyes at 1 day and in 98% of eyes at 6 and 12 months postoperatively. Group 4 consisted of 38 eyes. The mean SE was - 11.09 +/- 1.10 D preoperatively and - 1.25 +/- 1.20 D at 1 month, - 1.13 +/- 1.30 D at 6 months and - 1.20 +/- 1.25 D at 12 months postoperatively. Uncorrected VA was 20/40 or better in 78% of eyes at 1 day, in 94% at 6 months and in 90% at 12 months postoperatively. Intraoperative complications (free cap) occurred in two eyes and postoperative complications were observed in three eyes, making the total complications rate 1.29% (5/386). Seven eyes lost one Snellen line of BCVA, five lost two lines and two lost more than two lines (total: 3.64%, 14/386). CONCLUSION: In conclusion, LASIK is effective, predictable and safe for correcting myopia but is more accurate for correcting myopia up to -10.00 D. With more improvement in algorithms and ablation profile, we believe that LASIK can offer better results for higher myopia.

Adult↗
PubMed2004

Comparison of ablation centration in initial and retreatment active eye-tracker-assisted laser in situ keratomileusis and the effect on visual outcome.

PURPOSE: To evaluate the relationship between initial and retreatment ablation centers in active eye-tracker-assisted myopic laser in situ keratomileusis (LASIK) and determine whether the relationship between the 2 ablation centers influences the visual outcome after retreatment. SETTING: Department of Ophthalmology, China Medical University Hospital, Taichung, Taiwan. METHODS: This retrospective study comprised 21 eyes of 15 patients who had retreatment at least 3 months after primary myopic LASIK by lifting the initial flap. Corneal topography and best corrected visual acuity (BCVA) were evaluated preoperatively and 3 months postoperatively. The ablation centration was analyzed by corneal topography preoperatively and at 3 months. RESULTS: The mean decentration of the primary treatment was 0.43 mm +/- 0.21 (SD) and of the retreatment, 0.34 +/- 0.15 mm. There was no significant difference between them (P =.07). The 2 ablation centers were close each other. The mean distance between the 2 ablation centers was 0.29 +/- 0.18 mm and the mean angle between them, 39.7 +/- 46.2 degrees. The BCVA was unchanged after retreatment regardless of the relationship between the 2 ablation centers. CONCLUSIONS: With an active eye-tracking system, the retreatment center was not only close to the pupil center but also close to the primary ablation center. Regardless of the relationship between the 2 ablation centers, the BCVA did not change if the retreatment ablation was well centered.

Adult↗
PubMed2003

Intravitreous recombinant tissue plasminogen activator and gas to treat submacular hemorrhage in age-related macular degeneration.

We evaluated the safety and efficacy of intravitreous recombinant tissue plasminogen activator (rTPA) and gas for the treatment of submacular hemorrhage in age-related macular degeneration (ARMD). From January 2000 to April 2002, we enrolled 15 patients with submacular hemorrhage secondary to ARMD. All patients received 100 microg rTPA and 0.3 mL perfluoropropane intravitreously. Postoperatively, all patients were kept in a supine position for 4 hours followed by a face-down position for 4 days. Anatomic and functional results were evaluated during a follow-up period of 6 to 19 months. Submacular blood was completely displaced in 12 patients (80%) and partially in three (20%). Best postoperative visual acuity improved in all 15 eyes; in seven eyes (47%), the improvement was two or more lines. Final visual acuity improved in 12 eyes, remained stable in two eyes, and worsened in one eye. Onset of hemorrhage within 21 days was associated with better gains of lines in best postoperative (p = 0.0256) and final visual acuity (p = 0.044). Although two patients developed mild breakthrough vitreous hemorrhage within 1 day after treatment, no rTPA-related retinal toxicity was observed. Intravitreous injections of rTPA and gas are safe and effective in improving visual acuity in patients with submacular hemorrhage secondary to ARMD. Although the final visual outcome is often limited by the progression of the disease, significant and stable visual recovery over an extended follow-up period is possible using this easy and convenient technique.

Aged↗
PubMed2002

Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature.

PURPOSE: To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C. METHODS: Case report and MEDLINE review of the medical literature on scleral dellen after bare sclera technique. RESULTS: A 48-year-old man had a left nasal pterygium excised by the bare sclera technique with intraoperative mitomycin C. Eight days after surgery, the patient noticed a small black spot in the bare sclera area with mild irritation. Slit-lamp examination revealed a focal area of extreme thinning, centered on the nonepithelialized bare sclera, surrounded by edematous conjunctiva. The ciliary body was visible through the thin and dry scleral lesion. After topical lubricant therapy, the scleral lesion appeared normal thickness and white in color 3 days later. Therapy was continued until the sclera epithelialized. CONCLUSIONS: Scleral dellen is an early postoperative complication of bare sclera technique owing to delayed conjunctival wound closure. Hydration of the thinned sclera will rapidly thicken it. However, medical therapy should be continued until the surrounding conjunctiva has flattened and the sclera has epithelialized. Surgical wound closure is an alternative management and may be the way to prevent scleral dellen formation after bare sclera technique. All patients after bare sclera surgery should be followed up until the conjunctival wound has healed. If delayed healing is found, frequent artificial tears, patching, or surgical intervention is necessary.

Acute Disease↗
PubMedDate not supplied

Spontaneous regression of dense epithelial ingrowth after laser in situ keratomileusis.

PURPOSE: To present a case of dense epithelial ingrowth after laser in situ keratomileusis (LASIK) that spontaneously regressed 20 months after surgery. METHODS: A 34-year-old woman underwent bilateral LASIK. On postoperative day 1, a large downward displacement of the flap in the right eye was observed. The flap was repaired; however, epithelial ingrowth from the flap edge was noted 1 month later at the 1, 5, 8, and 11 o'clock positions. RESULTS: At 4-month follow-up, the epithelial ingrowth was stable at the 1, 8, and 11 o'clock positions but a dense sheet of epithelium was noted at the 5 o'clock position. At 15 months postoperatively, all epithelial ingrowth had resolved except for that at the 5 o'clock position. At 20 months postoperatively, the ingrowth at the 5 o'clock position had also regressed. CONCLUSIONS: Dense epithelial ingrowth does not always require surgical intervention. Surgery is necessary only when the epithelium appears to be progressing, affects visual function, or causes flap melting.

Adult↗
PubMedDate not supplied

Retinal phlebitis after LASIK.

PURPOSE: To report a case of retinal phlebitis with cystoid macular edema in both eyes 8 weeks after LASIK. METHODS: A 30-year-old woman underwent bilateral myopic LASIK. Eight weeks postoperatively, the patient experienced blurred vision in the left and right eyes. Fundus examination showed focal whitish patches in the parafoveal and juxtafoveal areas and lack of foveal reflex in both eyes. A diagnosis of retinal phlebitis with cystoid macular edema was made, which was treated with oral corticosteroids with tapering dose. RESULTS: Visual acuity returned to normal and the whitish fundus patches decreased in number and size in both eyes. CONCLUSIONS: Surgeons should be aware of potential risks and retinal complications associated with LASIK.

Adult↗
PubMedDate not supplied

Comparison of ablation centration after bilateral sequential versus simultaneous LASIK.

PURPOSE: To compare ablation centration after bilateral sequential and simultaneous myopic LASIK. METHODS: A retrospective randomized case series was performed of 670 eyes of 335 consecutive patients who had undergone either bilateral sequential (group 1) or simultaneous (group 2) myopic LASIK between July 2000 and July 2001 at the China Medical University Hospital, Taichung, Taiwan. The ablation centrations of the first and second eyes in the two groups were compared 3 months postoperatively. RESULTS: Of 670 eyes, 274 eyes (137 patients) comprised the sequential group and 396 eyes (198 patients) comprised the simultaneous group. Three months post-operatively, 220 eyes of 110 patients (80%) in the sequential group and 236 eyes of 118 patients (60%) in the simultaneous group provided topographic data for centration analysis. For the first eyes, mean decentration was 0.39 +/- 0.26 mm in the sequential group and 0.41 +/- 0.19 mm in the simultaneous group (P = .30). For the second eyes, mean decentration was 0.28 +/- 0.23 mm in the sequential group and 0.30 +/- 0.21 mm in the simultaneous group (P = .36). Decentration in the second eyes significantly improved in both groups (group 1, P = .02; group 2, P < .01). The mean distance between the first and second eyes was 0.31 +/- 0.25 mm in the sequential group and 0.32 +/- 0.18 mm in the simultaneous group (P = .33). The difference of ablation center angles between the first and second eyes was 43.2 < or = 48.3 degrees in the sequential group and 45.1 +/- 50.8 degrees in the simultaneous group (P = .42). CONCLUSIONS: Simultaneous bilateral LASIK is comparable to sequential surgery in ablation centration.

Adult↗
PubMedDate not supplied

Congenital reduplication of the lacrimal punctum and canaliculus in a patient with dry eye.

A healthy 60-year-old woman presented with bilateral dry eye syndrome that was more pronounced in the right eye than in the left eye. Two patent independent supernumerary puncta and canaliculi were found in the right upper eyelid. This condition may explain the more severe dryness in her right eye. Successful punctum occlusion was accompanied by marked resolution of symptoms in both eyes.

Dry Eye Syndromes↗