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Biomedical subjects

Janet B Croft

Publications and source records attributed to Janet B Croft.

At least 37 records · Page 2Linked to original sources
PubMed2005

Disparities in chronic disease risk factors and health status between American Indian/Alaska Native and White elders: findings from a telephone survey, 2001 and 2002.

We compared prevalence estimates of chronic disease risk factors and health status between American Indian/Alaska Native (AIAN) and White elders. We used 2001 and 2002 Behavioral Risk Factor Surveillance System data to estimate the prevalence of smoking, physical inactivity, obesity, diagnosed diabetes, and general health status. For all health behavior and status measures, American Indians/Alaska Natives reported greater risk than did Whites. Risk factors among AIAN elders need to be addressed to eliminate disparities in chronic diseases.

Alaska↗
PubMed2005

Racial differences in the use of aspirin: an important tool for preventing heart disease and stroke.

BACKGROUND: Regular aspirin use, particularly as secondary prevention, reduces morbidity from heart disease and stroke. Few studies have examined racial/ethnic differences in aspirin use for the prevention of cardiovascular disease (CVD). METHODS: Data from the 2001 Behavioral Risk Factor Surveillance System (n=2,514 African Americans; n=865 Hispanics; n=28,038 Whites) were used to assess racial/ethnic differences in aspirin use. Multivariable logistic regression was used to examine whether the likelihood of aspirin use differs by race/ethnicity after accounting for sociodemographic and CVD risk factors. RESULTS: Regular aspirin use was associated with increasing age, male gender, lower educational attainment, hypertension, diabetes, overweight, and histories of myocardial infarction, coronary heart disease, and stroke. Aspirin use was lower among African Americans and Hispanics than Whites (28.6% and 28.7% vs 37.1%, respectively). After adjustment for sociodemographic and CVD risk factors, African Americans and Hispanics were 30%-40% less likely than Whites (OR=0.6, 95% C1=0.5, 0.7, African Americans; OR=0.7, 95% CI=0.5, 1.0, Hispanics) to take aspirin. Although aspirin use was higher among those with CVD (73.6% African Americans, 73.6% Hispanics, and 82.7% Whites), after multivariable adjustment, African Americans and Hispanics with CVD remained 30% to 50% less likely to use aspirin than Whites (OR=0.7, 95% CI=0.4, 1.2, African Americans; OR=0.5, 95% CI=0.2, 1.1, Hispanics). CONCLUSIONS: African Americans and Hispanics are less likely to take aspirin than their White counterparts. Differences in sociodemographic characteristics and CVD risk factors do not account for lower aspirin use among racial/ethnic minorities. Additional studies should examine methods to increase aspirin use in these populations.

Adult↗
PubMed2004

Prevalence of heart disease and stroke risk factors in persons with prehypertension in the United States, 1999-2000.

BACKGROUND: Recent guidelines classify persons with above-optimal blood pressure (BP) but not clinical hypertension as having prehypertension. METHODS: Data were analyzed for 3488 persons aged 20 years and older with BP measured in the 1999-2000 National Health and Nutrition Examination Survey. The prevalence of risk factors-above-normal (> or =200 mg/dL [> or =5.17 mmol/L]) and high (> or =240 mg/dL [> or =6.21 mmol/L]) total cholesterol levels, diabetes mellitus, current smoker, and overweight or obesity-and the number of risk factors present were compared among BP groups (normotension, prehypertension, and hypertension). Multivariable logistic regression included age, sex, and race/ethnicity as covariates. RESULTS: Overall, 39% of persons were normotensive,31% were prehypertensive, and 29% were hypertensive. The age-adjusted prevalence of prehypertension was greater in men (39.0%) than in women (23.1%). African Americans aged 20 to 39 years had a higher prevalence of prehypertension (37.4%) than whites (32.2%) and Mexican Americans (30.9%), but their prevalence was lower at older ages because of a higher prevalence of hypertension. The probabilities of above-normal cholesterol levels, overweight/obesity, and diabetes mellitus were greater for persons with prehypertension vs normotension, whereas the probability of currently smoking was lower. Persons with prehypertension were 1.65 times more likely to have at least 1 other adverse risk factor than were those with normotension (P<.001). Among participants with prehypertension, there were no significant race/ethnic or sex differences in the likelihood of having at least 1 other risk factor. CONCLUSIONS: The greater prevalence of risk factors in persons with prehypertension vs normotension suggests the continued need for early clinical detection and intervention of prehypertension and comprehensive preventive and public health efforts.

Adult↗
PubMed2004

Racial and ethnic disparities in cardiovascular risk factors among stroke survivors: United States 1999 to 2001.

BACKGROUND AND PURPOSE: Stroke mortality is higher among US blacks than it is among US whites. Few studies have examined racial and ethnic differences in the prevalence of cardiovascular disease (CVD) risk factors among stroke survivors, especially among Hispanics. METHODS: Data are from 96 501 persons aged 18 years or older who participated in the 1999, 2000, or 2001 National Health Interview Survey, a continuous annual household-based survey of the US population. Participants reported a history of stroke, hypertension, diabetes, myocardial infarction, and coronary heart disease. Other CVD risk factors were current smoking, overweight/obese, inadequate physical activity, and binge drinking. RESULTS: Stroke was reported by 2.8% of blacks, 1.3% of Hispanics, and 2.2% of whites. Among 2265 stroke survivors, blacks were 1.65-times more likely (95% CI, 1.55 to 1.75) and Hispanics were 0.73-times less likely (95% CI, 0.69 to 0.78) than whites to report hypertension. Hispanics and blacks were more likely than whites to report diabetes (P<0.05). Hispanics and blacks were less likely than whites to report total coronary heart disease (P<0.05). Overweight was 1.63-times higher among blacks (95% CI, 1.55 to 1.73) and 1.36-times higher (95% CI, 1.30 to 1.44) among Hispanics than whites. Blacks were 1.82-times more likely (95% CI, 1.71 to 1.94) and Hispanics 2.09-times more likely (95% CI, 1.98 to 2.22) than whites to report inadequate levels of physical activity. Binge drinking and smoking were less common among Hispanics and Blacks than among whites (P<0.05). CONCLUSIONS: Racial and ethnic disparities exist in stroke prevalence and CVD risk behaviors and medical history. Targeted secondary prevention will be important in reducing disparities among Hispanic and black stroke survivors.

Adult↗
PubMed2004

Quality of heart failure care in managed Medicare and Medicaid patients in North Carolina.

Use of angiotensin-converting enzyme (ACE) inhibitors and beta-adrenergic receptor blockers in patients with heart failure (HF) remains low despite the results of clinical trials and evidence-based guidelines that support their use. The quality of HF care in managed Medicare and Medicaid programs in North Carolina participating in a HF quality improvement program was assessed. Managed care plans identified adult patients with 1 inpatient or 3 outpatient claims for HF during 2000. A stratified random sample of 971 Medicare and 642 Medicaid patients' outpatient medical records from 5 plans were reviewed by trained nurse abstractors to obtain data regarding type of HF, demographics, comorbidities, and therapies. Left ventricular function assessment was performed in 88% of patients. Among 494 patients with systolic dysfunction, 86% were appropriately treated with respect to ACE inhibitors (73% prescribed, 13% had a documented contraindication). In contrast, beta-blocker therapy was appropriate in 61% (49% prescribed, 12% contraindication). There were no significant differences in drug use by insurance, gender, race, or age. Ventricular function assessment and ACE inhibitor prescription rates are higher than beta-blocker prescription rates among Medicare and Medicaid managed care patients in North Carolina. Opportunities for improvement remain, particularly for beta-blocker use.

Adrenergic beta-Antagonists↗
PubMed2004

Trends in self-reported multiple cardiovascular disease risk factors among adults in the United States, 1991-1999.

BACKGROUND: There are few national- and state-level data on multiple cardiovascular disease (CVD) risk factor status and trends over time. We examined the prevalence of self-reported multiple CVD risk factors from 1991 through 1999. METHODS: The Behavioral Risk Factor Surveillance System is a state-based telephone survey of adults 18 years or older. Surveys in 1991, 1993, 1995, 1997, and 1999 ascertained reported high blood pressure, high blood cholesterol level, diabetes, obesity, and current smoking status. Trends in the prevalence of persons with each risk factor and of having 2 or more risk factors were calculated. Data were age standardized to the 2000 US population. RESULTS: From 1991 to 1999, the prevalence of reported high blood pressure increased from 23.8% to 25.4%, high cholesterol levels increased from 24.9% to 27.7%, diabetes increased from 5.5% to 7.1%, obesity increased from 13.5% to 20.3%, and smoking remained at approximately 21%. The prevalence of adults with 2 or more risk factors increased from 23.6% in 1991 to 27.9% in 1999 and significantly increased for both men and women and for all race or ethnic, age, and education groups. Among states, the prevalence of multiple risk factors ranged from 15.0% to 29.9% in 1991 and from 18.7% to 37.1% in 1999. From 1991 to 1999, the prevalence of multiple risk factors increased by 10% or more in 36 states. CONCLUSIONS: The substantial proportion of persons with known multiple risk factors (25% of the population) suggests that increased CVD prevention and risk factor reduction efforts should focus on comprehensive risk reduction strategies.

Adolescent↗
PubMed2004

Public recognition of major signs and symptoms of heart attack: seventeen states and the US Virgin Islands, 2001.

BACKGROUND: Timely access to emergency cardiac care and survival is partly dependent on early recognition of heart attack symptoms and immediate action by calling emergency services. We assessed public recognition of major heart attack symptoms and knowledge to call 9-1-1 for an acute event. METHODS: Data are from the 2001 Behavioral Risk Factor Surveillance System, a state-based telephone survey. Participants (n = 61,018) in 17 states and the U.S. Virgin Islands indicated whether the following were heart attack symptoms: pain or discomfort in the jaw, neck, back; feeling weak, lightheaded, faint; chest pain or discomfort; sudden trouble seeing in 1 or both eyes (false symptom); pain or discomfort in the arms or shoulder; shortness of breath. Participants also indicated their first action if someone was having a heart attack. RESULTS: Most persons (95%) recognized chest pain as a heart attack symptom. However, only 11% correctly classified all symptoms and knew to call 9-1-1 when someone was having a heart attack. Symptom recognition and the need to call 9-1-1 was lower among men than women, persons of various ethnic groups than whites, younger and older persons than middle-aged persons, and persons with less education. Persons with high blood pressure, high cholesterol, diabetes mellitus, or prior heart attack or stroke were not appreciably more likely to recognize heart attack symptoms than were persons without these conditions. CONCLUSIONS: Public health efforts are needed to increase recognition of the major heart attack symptoms in both the general public and groups at high risk for an acute event.

Adult↗
PubMed2004

Inpatient smoking-cessation counseling and all-cause mortality among the elderly.

BACKGROUND: Although smoking cessation is essential to the management of acute myocardial infarction (AMI), prevalence and benefits of smoking-cessation counseling in the inpatient setting are not well described among older adults. The objective of this study was to evaluate associations between inpatient smoking-cessation counseling and 5-year all-cause mortality among older adults hospitalized with AMI. METHODS: The Cooperative Cardiovascular Project (January 1994-July 1995) included 788 Medicare beneficiaries aged >/=65 years who were current smokers, admitted to acute care facilities in North Carolina with confirmed AMI, and discharged alive. Information on smoking-cessation advice or counseling prior to discharge was abstracted from medical records. Associations of counseling with 5-year risk of death were assessed with multivariate Cox proportional hazards regression. RESULTS: Smoking-cessation counseling was provided to 40% of AMI patients before discharge. Women (p =0.06) and blacks (p =0.02) were less likely to receive counseling. Counseling was associated with a history of chronic obstructive pulmonary disease (p =0.01). Increasing age, discharge to a skilled nursing facility, and histories of hypertension, heart failure, or stroke were associated with no counseling (p <0.05, all cause). Age-adjusted mortality rates (per 1000 enrollees) at 5 years were 488.3 for patients who were given counseling compared to 579.3 for patients without counseling. After adjustment for age, race, gender, prior histories of hypertension, cardiovascular diseases, diabetes, and chronic obstructive pulmonary disease, Killip class III or IV, and discharge to a skilled nursing facility; inpatient counseling remained associated with improved survival (relative hazard, 0.78; 95% confidence interval, 0.63-0.97). CONCLUSIONS: Inpatient counseling on smoking cessation is suboptimal among older smokers hospitalized with AMI. Even without confirmation of actual cessation, these data suggest that provision of smoking-cessation advice or counseling has a major impact on survival of older adults.

Age Factors↗
PubMed2004

Associations between white blood cell count and risk for cerebrovascular disease mortality: NHANES II Mortality Study, 1976-1992.

PURPOSE: To examine associations between elevated white blood cell count (WBC) and cerebrovascular disease (CeVD) mortality independent of cigarette smoking and by gender. METHODS: We used Cox regression analyses of data from 8459 adults (3982 men; 4477 women) aged 30 to 75 years in the NHANES II Mortality Study (1976-1992) to estimate the relative risk of death from CeVD across quartiles of WBC. RESULTS: During 17 years of follow-up, there were 192 deaths from CeVD (93 men; 99 women). Compared with those with WBC (cells/mm(3))<5700, adults with WBC>8200 were at increased risk of CeVD mortality (relative risk [RR], 2.1; 95% confidence interval [CI], 1.2-3.7) after adjustment for smoking and other cardiovascular disease risk factors. Similar results were observed among never smokers (RR, 2.0; 95% CI, 1.0-3.8). The adjusted relative risk of CeVD mortality comparing those with WBC>8200 to those with WBC<5700 was 1.5 (95% CI, 0.7-3.5) among men and 2.7 (95% CI, 1.4-5.0) among women. CONCLUSIONS: Elevated WBC may predict CeVD mortality even after considering the effects of smoking and other cardiovascular disease risk factors.

Adult↗
PubMed2004

Trends in hypertension-related death in the United States: 1980-1998.

Trends in hypertension-related mortality for groups by race/ethnicity, sex, and age have not been examined previously. National multiple-cause mortality files for 1980-1998 were analyzed for adult decedents with hypertension listed as one of 20 conditions causing death. Racial/ethnic comparisons of hypertension-related death were performed using age-standardized and age-specific rates in years (per 100,000). Age-standardized rate increased from 183.1 in 1980 to 243.7 in 1998, a relative increase of 33% and an average annual increase of 1.5% (p<0.0001). From 1981 to 1998, age-specific death rates increased for persons > or =85 years (average annual increase of 10.4% for blacks, 7.9% for whites), 75-84 years (5.9% for blacks, 3.6% for whites), and 65-74 years (3.2% for blacks, 1.4% for whites). By 1997-1998, blacks had greater death rates compared with whites at all ages. Over the past two decades, there has been a step-by-step increase in hypertension-related mortality, which has continued to show a male over female and black over white predominance. Prevention and control of hypertension must continue to be pursued as a strategy to reduce cardiovascular disease morbidity and mortality.

Age Distribution↗
PubMed2003

Increasing trends in hospitalization for atrial fibrillation in the United States, 1985 through 1999: implications for primary prevention.

BACKGROUND: Atrial fibrillation, the most common sustained disturbance of heart rhythm, is associated with a 5-fold increase in the incidence of ischemic stroke. METHODS AND RESULTS: The National Hospital Discharge Survey was used to estimate the annual number and prevalence of hospitalizations with atrial fibrillation among men and women 35 years of age or older. From 1985 through 1999, hospitalizations increased from 154 086 to 376 487 for a first-listed diagnosis and from 787 750 to 2 283 673 for any diagnosis. Prevalence was higher among successive age groups. Age-standardized prevalence was consistently higher among men than women. In 1999, essential hypertension, ischemic heart disease, congestive heart failure, and diabetes were prominent coexisting conditions. The number of male patients discharged home decreased from 77% to 63%, whereas the number of discharges to long-term care increased from 9% to 15%; the corresponding values for women were 72% to 56% and 15% to 23%. A slight increase in discharges to short-term care was indicated, whereas no trends were noted for in-hospital mortality. CONCLUSIONS: Hospitalizations for atrial fibrillation have increased dramatically (2- to 3-fold) in recent years. The public health burden of atrial fibrillation is enormous and expected to continue to increase over the next decades. Primary prevention of atrial fibrillation must be recognized and pursued as a complementary management strategy for reducing cardiovascular morbidity and mortality.

Adult↗
PubMed2003

Low public recognition of major stroke symptoms.

BACKGROUND: A Healthy People 2010 objective includes increasing public awareness of the warning signs of stroke, yet few data exist about the level of awareness. Recognition of stroke symptoms and awareness of the need to call 911 for acute stroke events were examined among the general population. METHODS: Data are from 61,019 adults participating in the 2001 Behavioral Risk Factor Surveillance System, a state-based telephone survey. Respondents indicated whether the following were symptoms of stroke: confusion/trouble speaking; numbness/weakness of face, arm, or leg; trouble seeing; chest pain (false symptom); trouble walking, dizziness, or loss of balance; and severe headache with no known cause. Persons also reported the first action they would take if they thought someone was having a stroke. RESULTS: Only 17.2% of respondents overall (5.9% to 21.7% by state) correctly classified all stroke symptoms and indicated that they would call 911 if they thought someone was having a stroke. Recognition of all symptoms and knowledge of when to call 911 were comparable by gender but lower among ethnic minorities, younger and older people, those with less education, and current smokers compared to whites, middle-aged people, those with more education, and nonsmokers, respectively. There were no substantive differences by history of hypertension, diabetes, heart disease, or stroke. CONCLUSIONS: Public recognition of major stroke symptoms is low. Educational campaigns to increase awareness among the general population and targeted messages to those at high-risk persons and their families may help to improve time to treatment for adults suffering acute strokes.

Adult↗
PubMed2003

Associations between short- and long-term unemployment and frequent mental distress among a national sample of men and women.

Unemployment has been associated with poor psychologic well-being. Using data from the 2001 Behavioral Risk Factor Surveillance System, we examined relationships between unemployment and frequent mental distress (FMD), defined as 14 or more mentally unhealthy days during the previous 30 days, among 98,267 men and women aged 25-64 years. The age-standardized prevalence of FMD was 6.6% (standard error, 0.14) among employed adults, 14.0% (2.00) among adults unemployed >1 year, and 15.5% (1.18) among those unemployed <1 year. After adjustment, the relative odds of FMD were 2.09 (95% confidence interval [CI] = 1.75-2.50) for adults unemployed <1 year and 1.88 (95% CI = 1.31-2.71) for adults unemployed >1 year compared with employed adults. Similar patterns were observed across gender, race/ethnicity, education, income, and area unemployment groups. Unemployed persons are a population in need of public health intervention to reduce the burden of mental distress. Public health officials should work with government officials to incorporate the health consequences of unemployment into economic policymaking.

Adult↗
PubMed2003

Establishing data elements for the Paul Coverdell National Acute Stroke Registry: Part 1: proceedings of an expert panel.

BACKGROUND AND PURPOSE: Stroke is the third-leading cause of death and a leading cause of disability in adults in the United States. In recent years, leaders in the stroke care community identified a national registry as a critical tool to monitor the practice of evidence-based medicine for acute stroke patients and to target areas for continuous quality of care improvements. An expert panel was convened by the Centers for Disease Control and Prevention to recommend a standard list of data elements to be considered during development of prototypes of the Paul Coverdell National Acute Stroke Registry. METHODS: A multidisciplinary panel of representatives of the Brain Attack Coalition, professional associations, nonprofit stroke organizations, and federal health agencies convened in February 2001 to recommend key data elements. Agreement was reached among all participants before an element was added to the list. RESULTS: The recommended elements included patient-level data to track the process of delivering stroke care from symptom onset through transport to the hospital, emergency department diagnostic evaluation, use of thrombolytic therapy when indicated, other aspects of acute care, referral to rehabilitation services, and 90-day follow-up. Hospital-level measures pertaining to stroke center guidelines were also recommended to augment patient-level data. CONCLUSIONS: Routine monitoring of the suggested parameters could promote community awareness campaigns, support quality improvement interventions for stroke care and stroke prevention in each state, and guide professional education in hospital and emergency system settings. Such efforts would reduce disability and death among stroke patients.

Advisory Committees↗
PubMed2003

Increasing trends in pre-transport stroke deaths--United States, 1990-1998.

OBJECTIVE: We examined national trends in places where stroke deaths occurred. METHODS: National vital statistics data (1990-1998) for stroke death (ICD-9 codes 430-438) were analyzed for place of death by selected socio-demographic characteristics and stroke subtype. RESULTS: Half of all stroke deaths in 1998 occurred in-hospital, 46.1% occurred pre-transport, 0.6% were dead on arrival, and 3.3% occurred in the emergency department. Pre-transport deaths accounted for 55.0% of ischemic strokes, 12.8% of intracerebral strokes, and 12.9% of subarachnoid hemorrhagic strokes. The proportions of stroke deaths occurring pre-transport increased from 1990 through 1998 by 22.9% for all strokes, by 25.3% for ischemic, and by 24.3% for hemorrhagic stroke deaths. CONCLUSIONS: Almost half of stroke deaths occur prior to hospital admission. Research must identify factors that promote more timely access to effective medical care. Further efforts are needed to increase public awareness about stroke symptoms in order to reduce both delays in seeking treatment, and untimely deaths from stroke.

Adolescent↗
PubMed2002

Increased atrial fibrillation mortality: United States, 1980-1998.

The authors used death certificate data to evaluate national trends in the reporting of atrial fibrillation as an underlying or contributory cause of death for groups defined by age (45 years or older), sex, and race (Black vs. White) and to examine comorbidity. The multiple-causes mortality files from 1980 through 1998 were analyzed for decedents, with atrial fibrillation (International Classification of Diseases, Ninth Revision, code 427.3) listed as one of up to 20 conditions causing death. The number of decedents with atrial fibrillation increased from 18,947 in 1980 to 61,946 in 1998, and the proportion with atrial fibrillation reported as the underlying cause of death rose from 8.3% in 1980 to 11.6% in 1998. Age-standardized death rates from 1980 to 1998 were consistently highest among White men, followed (in descending order) by White women, Black men, and Black women. Overall, the age-standardized rate (per 100,000) increased from 27.6 in 1980 to 69.8 in 1998 (an average annual increase of 5.4%, p < 0.0001). Ischemic heart disease was the most frequent underlying cause of death among decedents with atrial fibrillation (26.8%). These findings emphasize the need for increased application of proven prevention and control measures to decrease associated cardiovascular morbidity and mortality.

Black or African American↗