Biomedical subjects
Jason F Okulicz
Publications and source records attributed to Jason F Okulicz.
Human monocytic ehrlichiosis in a renal transplant patient.
Human ehrlichiosis is an emerging pathogen in immunocompromised patients, potentially leading to increased morbidity compared to immunocompetent patients. A high index of suspicion is imperative and early treatment with doxycycline can be life-saving. We report the case of an immunosuppressed renal transplant patient who was diagnosed with human monocytic ehrlichiosis and successfully treated with doxycycline.
Mycobacterium tuberculosis infection of a presumed Charcot joint.
A 65-year-old male with peripheral neuropathy and small lymphocytic lymphoma presented with erythema and edema of the left foot. A Charcot midfoot was diagnosed and treated with a total contact cast and restricted weight bearing. However, subsequent analysis of bone and synovial fluid months later revealed Mycobacterium tuberculosis infection.
Cutaneous onchocercoma.
Onchocerciasis is a common, chronic multisystem disease with dermatologic, ocular, and systemic manifestations. Although the disease is endemic in Africa, Latin America, and Yemen, imported cases have been described in the United States. The causative organism, Onchocerca volvulus, is transmitted by the bite of a black fly of the genus Simulium. There are a number of cutaneous manifestations of the disease, including onchocercomas, which are subcutaneous bundles of worms. The antiparasitic agent ivermectin is the drug of choice for both prophylaxis and treatment of active disease.
Hereditary and acquired ichthyosis vulgaris.
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Epidermolysis bullosa simplex.
Blistering is a common occurrence generally caused by moderate or repetitive trauma to the skin. Blistering due to minor trauma is less common and may be associated with a group of heterogeneous genetic diseases called epidermolysis bullosa (EB). The level of vesiculation within the skin defines 3 major subtypes of EB: EB simplex (EBS), dystrophic EB, and junctional EB. We will review the simple type-EBS.