Biomedical subjects

Jason Lee

Publications and source records attributed to Jason Lee.

21 records · Page 2Linked to original sources

PubMed2002

Lymphocyte traffic in lymphoid organ neogenesis: differential roles of Ltalpha and LTalphabeta.

In these studies the differential roles of LTalpha and LTalphabeta complex have been discussed with regard to development of lymphoid organs in ontogeny and in inflammation, LTalpha is necessary for PLNand MLN, most likely as both LTalpha and LTalphabeta complex, whereas only LTalphabeta is required for MLN. Both are involved in the cellularity of the NALT. When expressed as a transgene, LTa alone can induce cellular accumulation and MAdCAM, but not PNAd, an epitope associated with PLN HEV. These data suggest that LTalphabeta complex plays a crucial role in PNAd. One hypothesis is that LTalphabeta induces PNAd through modification via an HEV sulfotransferase. RIPLTalpha.RIPLTbeta mice will provide an important tool to investigate this question.

Animals↗

PubMedDate not supplied

A community expands access to health care: the case of access health in Michigan.

Access Health, a Michigan-based "three-share plan," is viewed as a successful community-based approach to expanding health benefits in the workplace. It was the stimulus for recently proposed legislation to federally fund similar plans nationally. The program evolved with the support of the W.K. Kellogg Foundation. Its sustained viability is attributable in part to the creative use of a state statute to draw down federal Medicaid disproportionate-share hospital (DSH) funds. Although it faces obstacles common to programs of its type, the program's greatest financial vulnerability rests on the uncertain continued availability of the monies it uses to subsidize the program.

Community Participation↗

PubMedDate not supplied

The adoption gap: health information technology in small physician practices. Understanding office workflow can help realize the promise of technology.

Health information technology (HIT) can promote higher quality, lower costs, and increased patient and clinician satisfaction. Yet small practice settings (where the vast majority of patient care is provided) have been slow to adopt HIT products and services. Successful adoption requires close attention to office workflow, or how tasks are organized and resources used to achieve outcomes. HIT improvements in the small physician office setting are achieved through strong leadership, strategic planning, process reengineering, change management, and customizing IT systems to match and support desired office workflows and health care outcomes.

Diffusion of Innovation↗