PubMed Health⌕ Search

Biomedical subjects

Javier M Romero

Publications and source records attributed to Javier M Romero.

9 recordsLinked to original sources
PubMed2006

Practical noninvasive neurovascular imaging of the neck arteries in patients with stroke, transient ischemic attack, and suspected arterial disease that may lead to ischemia, infarction, or flow abnormalities.

Stroke is the third leading cause of death in the United States, killing nearly 157,000 people a year with an estimated society cost of dollar 58 billion in 2006. A large percentage of ischemic strokes is secondary to extracranial carotid and vertebral arterial disease. While digital subtraction angiography has traditionally been used for the initial evaluation of the degree of stenosis, noninvasive imaging has moved to the forefront in the extracranial arterial evaluation. The importance of understanding the imaging techniques, findings, interpretation, artifacts, and pitfalls is essential to appropriate patient management.

Angiography, Digital Subtraction↗
PubMed2005

Noninvasive evaluation of carotid artery stenosis: indications, strategies, and accuracy.

Carotid artery occlusive disease is an important stroke risk factor and accounts for a significant proportion of stroke morbidity and mortality. In this article we survey the major clinical trials related to stroke risk in symptomatic and asymptomatic patients who have internal carotid artery (ICA) stenosis; techniques for noninvasive screening of ICA stenosis including ultrasound, MR angiography, and CT angiography; and evolving algorithms for ICA evaluation. We comment on current interest in plaque morphology as a risk factor for stroke.

Carotid Artery, Internal↗
PubMed2005

CT angiography source image evaluation for stroke.

Computed tomography angiogram of the head and neck has lately become a pivotal imaging modality in the patient with acute stroke symptoms due to its high resolution, accuracy, speed, and sensitivity in the assessment of brain parenchyma and vascular patency.

Cerebral Angiography↗
PubMed2002

Diffusion MR imaging of acute ischemic stroke.

Diffusion MR imaging provides unique information about the physiologic state of ischemic tissue. It is highly sensitive and specific in the detection of acute and hyperacute ischemic stroke and has greatly improved the diagnosis and treatment of acute stroke. The DWI abnormality provides information about clinical outcome and final infarct size. Diffusion combined with perfusion MR imaging provides information about the operational ischemic penumbra and final infarct size. Diffusion MR imaging seems to be promising in the evaluation of candidates for thrombolysis.

Acute Disease↗
PubMedDate not supplied

US of neurovascular occlusive disease: interpretive pearls and pitfalls.

Ultrasonography (US) of the head and neck is a convenient but operator-dependent screening tool for detection and diagnosis of neurovascular occlusive disease. In US examination of the extracranial carotid arteries, stenosis is most commonly graded according to the peak systolic Doppler velocity in the region of maximal luminal narrowing rather than according to the percentage of atheromatous plaque occupying the lumen. However, the peak systolic velocity is not always reliable in estimation of the degree of stenosis. General diagnostic pitfalls include technical difficulties with scanning, failure to review the spectral waveform patterns, the presence of additional stenotic lesions, and anatomic variants. Specific examples of pitfalls include tandem lesions, differentiation of pseudo-occlusion from true total occlusion, pseudonormalization of velocities in cases of very severe stenosis, lesions of the carotid artery origin or aortic valve, progression of subclavian steal, underestimation of severe stenosis due to heavily calcified plaque, a persistent trigeminal artery, and contralateral carotid artery stenosis. Although conventional angiography remains the standard of reference for assessment of carotid artery disease, recognition of these common sources of error in US can improve the accuracy of this noninvasive test in diagnosis of carotid artery occlusion.

Arterial Occlusive Diseases↗
PubMedDate not supplied

Total occlusion versus hairline residual lumen of the internal carotid arteries: accuracy of single section helical CT angiography.

BACKGROUND AND PURPOSE: Routine carotid sonography and MR angiography cannot reliably detect the markedly reduced flow velocities associated with very severe carotid stenosis. In this study, we sought to evaluate the accuracy of single row detector helical CT angiography in distinguishing hairline residual lumen from total occlusion of severely stenosed internal carotid arteries (ICAs). METHODS: From our departmental data base of single row detector CT angiography studies performed for evaluation of ICA occlusive disease, 21 cases were identified with evidence of either hairline residual lumen or total occlusion on correlative conventional catheter radiographic arteriograms; these included seven cases of proved hairline residual lumen and 14 cases of proved total occlusion. Two neuroradiologists, blinded to the radiographic arteriography results, graded the diseased ICA on each CT angiogram as definitely occluded, probably occluded, indeterminate, probably patent, or definitely patent. Receiver operating characteristic curves were generated for each neuroradiologist. RESULTS: At an operating point on the receiver operating characteristic curve corresponding to 90% sensitivity, the first reader achieved 95% specificity and the second reader achieved 80% specificity for distinguishing hairline residual lumen from total occlusion. Absolute accuracy rates were 95% and 85%, respectively. No significant difference in accuracy was observed between the two readers (P =.28, two-tailed t test). CONCLUSION: Single row detector CT angiography can distinguish total ICA occlusion from hairline residual lumen with a high degree of accuracy. In equivocal cases, conventional catheter arteriography may be desirable to confirm the diagnosis.

Aged↗