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Biomedical subjects

Jean-Noël A Argenson

Publications and source records attributed to Jean-Noël A Argenson.

9 recordsLinked to original sources
PubMed2006

The unicompartmental knee: design and technical considerations in minimizing wear.

Unicompartmental knee arthroplasty is an alternative to total knee arthroplasty for patients with unicompartmental tibiofemoral noninflammatory disease. Careful patient selection and newer instrumentation has reduced the progression of arthrosis in the other compartment and tibial loosening, leaving polyethylene wear as the predominant failure mechanism in more contemporary designs. Increased wear increases the debris volume at the bone-implant interface, and wear particles will generate osteolysis leading to component loosening and unreplaced compartment degeneration. The design-related factors that minimize wear include a polyethylene thickness of greater than 6 mm, a limited shelf age, and a design allowing large areas of contact mediolaterally and anteroposteriorly. Congruous mobile-bearing implants could play a substantial role in reducing wear if they are not associated with dislocation and nonreproducible surgical techniques. Important technical factors include accurate instrumentation avoiding component-to-component malposition and edge loading, allowing slight under-correction of the pre- operative deformity. The patient-related factors include a weight limit, a functional anterior cruciate ligament, and a correctable frontal deformity. Continued research including that related to cross-linking and sterilization methods is mandatory to improve polyethylene strength. A better understanding of kinematics and contact forces may provide long-term survival and patient satisfaction after unicompartmental arthroplasty.

Humans↗
PubMed2006

A 12-28-year followup study of closing wedge high tibial osteotomy.

Current indications for high tibial osteotomy (HTO) are controversial although several risk factors have been associated with HTO survival. We ascertained the influence of preoperative variables in a consecutive series of patients who had closing wedge HTO at a minimum of 12 year followup (mean 18-year, range 12 to 28 years). Three hundred one of an initial 372 high tibial osteotomies (313 patients) were included (81% followup); 71 knees were eliminated because patients died (30 knees) or were lost to followup (41 knees). The mean age was 42 years (range, 15-76 years), 194 were men and 119 were women. The osteotomy was fixed by a Blount staple and an AO half-tube plate with three screws. Forty-three knees (14%) in 39 patients were revised for progression of osteoarthritis at an average of 102 months. Survival was 85% at 20 years with revision as the endpoint. Knee function was considered satisfactory by 77% of patients. At final followup, 1/2 of the knees showed radiographic signs of medial osteoarthritis. The most important risk factors predicting revision were age greater than 50 years and a preoperative arthritis Ahlback grade of 3 or more.

Adolescent↗
PubMed2005

In vivo kinematic evaluation and design considerations related to high flexion in total knee arthroplasty.

In designing a posterior-stabilized total knee arthroplasty (TKA) it is preferable that when the cam engages the tibial spine the contact point of the cam move down the tibial spine. This provides greater stability in flexion by creating a greater jump distance and reduces the stress on the tibial spine. In order to eliminate edge loading of the femoral component on the posterior tibial articular surface, the posterior femoral condyles need to be extended. This provides an ideal femoral contact with the tibial articular surface during high flexion angles. To reduce extensor mechanism impingement in deep flexion, the anterior margin of the tibial articular component should be recessed. This provides clearance for the patella and patella tendon. An in vivo kinematic analysis that determined three dimensional motions of the femorotibial joint was performed during a deep knee bend using fluoroscopy for 20 subjects having a TKA designed for deep flexion. The average weight-bearing range-of-motion was 125 degrees . On average, TKA subjects experienced 4.9 degrees of normal axial rotation and all subjects experienced at least -4.4 mm of posterior femoral rollback. It is assumed that femorotibial kinematics can play a major role in patellofemoral kinematics. In this study, subjects implanted with a high-flexion TKA design experienced kinematic patterns that were similar to the normal knee. It can be hypothesized that forces acting on the patella were not substantially increased for TKA subjects compared with the normal subjects.

Arthroplasty, Replacement, Knee↗
PubMed2005

Patellofemoral arthroplasty: an update.

UNLABELLED: The rationale for presenting this updated study is to report long-term clinical and survival results of patellofemoral arthroplasty and to ascertain whether the preoperative diagnosis influenced outcomes and therefore indications. We retrospectively updated a previous evaluation of 66 patients who had unilateral patellofemoral arthroplasty between 1972 and 1990. The mean age of the patients at the initial surgery was 57 years (range, 21-82 years). The patients had an average followup of 16.2 years (range, 12-20 years). Preoperative diagnosis included instability, fracture, and primary arthritis. Revision surgery was done in 14 patients for femorotibial osteoarthritis, in 11 for loosening, and in four for stiffness. Survivorship was 58% at 16 years. The knee function score improved from 40 points preoperatively to 81 points at last followup. The best results were in patients with preoperative instability and corrected alignment of the extensor mechanism. Stiffness occurred only in those patients with osteoarthritis from previous fracture. Progressive degeneration of the tibiofemoral joint was noted mainly in the primary osteoarthritis etiologic group. This long-term evaluation of patellofemoral arthroplasty showed the importance of patient selection while excluding knees with significant frontal tibiofemoral malalignment. LEVEL OF EVIDENCE: Therapeutic study, Level IV-1 (case series). See the Guidelines for Authors for a complete description of levels of evidence.

Adult↗
PubMed2004

A high flexion total knee arthroplasty design replicates healthy knee motion.

Deep flexion affects both femorotibial contact pattern and the patellofemoral articulation. The purpose of this study was to compare the patellofemoral motion of nonimplanted and implanted knees and to analyze femorotibial kinematics after total knee replacement designed for deep flexion. Three-dimensional patellofemoral kinematics were evaluated during a deep knee bend using fluoroscopy for five control patients with a healthy knee, five patients with an anterior-cruciate-ligament-deficient knee, and 20 patients who had a high flexion total knee arthroplasty. Less translation of patellofemoral contact position was seen in patients who had knee replacements than in patients with healthy knees, but the average motion and the patella tilt angles were similar to the healthy knees. On average, patients who had a total knee arthroplasty had 4.9 degrees normal axial rotation, and all patients had at least -4.4 mm of posterior femoral rollback. The average weightbearing range of motion of the patients in the total knee arthroplasty group was 125 degrees . In this study, patients implanted with a high-flexion knee replacement design had kinematic patterns that were similar to the healthy knee. It can be hypothesized that forces acting on the patella were not substantially increased for patients who had a total knee arthroplasty compared with the control patients.

Anterior Cruciate Ligament↗
PubMed2002

In vivo determination of knee kinematics for subjects implanted with a unicompartmental arthroplasty.

Femorotibial contact positions for 20 subjects implanted with a unicompartmental knee arthroplasty (UKA) were analyzed using videofluoroscopy. Femorotibial contact paths were determined using a computer-automated model-fitting technique. Subjects having a medial UKA experienced on average -0.8 mm of posterior femoral rollback, whereas subjects having a lateral UKA experienced -2.5 mm of posterior femoral rollback. Twelve of 17 subjects having a medial UKA and 2 of 3 subjects having a lateral UKA experienced normal axial rotation (average, 3.3 degrees and 11.2 degrees ). The results for some subjects suggest that the anterior cruciate ligament was unable to thrust the femur anteriorly at full extension. These results support the findings that the anterior cruciate ligament plays a significant role in knee kinematics, which may contribute to UKA longevity.

Adult↗
PubMed2002

Modern unicompartmental knee arthroplasty with cement: a three to ten-year follow-up study.

BACKGROUND: Unicompartmental arthroplasty is a treatment alternative when only one compartment of the knee is affected with arthritis, but the reported results of this procedure have been variable. The purpose of the present study was to evaluate the results of a modern unicompartmental knee arthroplasty performed with use of a cemented metal-backed prosthesis and surgical instrumentation comparable with that used for total knee replacement. METHODS: The indications for the procedure were osteonecrosis or osteoarthritis associated with full-thickness loss of cartilage that was limited to one tibiofemoral compartment as evaluated on standing and stress radiographs. One hundred and sixty consecutive cemented metal-backed Miller-Galante prostheses in 147 patients were evaluated after a mean duration of follow-up of sixty-six months (range, thirty-six to 112 months). The mean age of the patients at the time of the index procedure was sixty-six years. RESULTS: Three knees were revised because of progression of osteoarthritis in the patellofemoral joint (two knees) or the lateral tibiofemoral compartment (one knee). Two knees had revision of the polyethylene liner. The average Hospital for Special Surgery knee score improved from 59 points preoperatively to 96 points at the time of the review. According to Kaplan-Meier analysis, the ten-year survival rate (with twenty-nine knees at risk) was 94% +/- 3% with revision for any reason or radiographic loosening as the end point. CONCLUSIONS: A modern unicompartmental knee arthroplasty is a valid alternative for patients with unicompartmental tibiofemoral noninflammatory disease. The patient selection must be strict with regard to the status of the patellofemoral joint. The preoperative planning includes stress radiographs to assess the correction of the deformity and the status of the uninvolved compartment. Continued long-term follow-up is necessary to evaluate long-term polyethylene wear.

Adult↗