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Biomedical subjects

Jenö Czigner

Publications and source records attributed to Jenö Czigner.

3 recordsLinked to original sources

Circumferential resection of crico-tracheal stenosis with primary end-to-end anastomosis.

Postintubation injury of the upper airway commonly results in stenotic lesions of the larynx, subglottis, and adjacent trachea. The traditional approach to surgical correction is staged plastic reconstruction. Reported results are variable and unpredictable, and permanent extubation is impossible in a significant number of patients. We present our experience with circumferential crico-tracheal resection with end-to-end anastomosis. Between 1991 and 2002 we performed this procedure on 29 patients with crico-tracheal stenosis. The cause of the stenosis was related to intubation and/or failed tracheotomy in 87% of the patients. Two to 7 tracheal rings were resected and a tension-free anastomosis was achieved with mobilization techniques that were limited to peritracheal dissection. The anastomosis success rate was 96%. Type of the anastomosis was tracheo-thyreopexy in six, tracheo-cricopexy in nine and tracheo-tracheopexy in eight cases. There were no major complications and no compromise of swallowing. This experience suggests that the procedure is relatively safe and effective.

Adult↗

Neural response telemetry in cochlear implant users.

Programming of multichannel cochlear implants requires subjective responses to a series of sophisticated psychophysical percepts. It is often difficult for cochlear implant patients (especially young prelinguistically deaf children) to provide adequate responses for device fitting. However, the neural response telemetry (NRT) system renders possible the measurement of the compound action potential threshold. We performed NRT examinations in 27 cochlear implant users with Nucleus 24-channel cochlear implants. Measurements were obtained from five electrodes (3, 5, 10, 15, and 20) in each patient. Our goal was to look for correlation between behavioral subjective thresholds and compound action potentials. The action potentials could be elicited in 23 patients in all measured electrodes. The NRT threshold values were highly correlated with electrical threshold levels obtained through subjective responses. Our results suggest that the electrically elicited neural responses may yield very important information for device fitting in patients with cochlear implants.

Child↗

Investigation of auditory brainstem function in diabetic patients.

We performed brainstem auditory evoked potential (BAEP) examinations in 15 patients with long-standing type 1 diabetes mellitus. We applied cardiovascular reflex tests for assessment of autonomic neuropathy. The aim of our investigation was to compare the BAEP results of this patient group with those of controls and to look for the possible correlation between alteration of the auditory brainstem function and cardiovascular autonomic neuropathy. Analysis of the latencies (waves I, II, III, and V) and the interpeak latencies (I-III and I-V) of BAEP revealed a significant difference between those of diabetics and those of healthy controls. The amplitudes of waves I, III, and V were definitely lower in comparison with amplitudes of healthy controls. We observed a positive correlation between the overall autonomic score and the latencies (waves III and V) and interpeak latencies (I-III, I-V). These data support the hypothesis that long-standing diabetes mellitus and diabetic neuropathy might be revealed as a cause of certain dysfunctions of the central auditory pathways.

Adult↗