Biomedical subjects

Jennie Si

Publications and source records attributed to Jennie Si.

3 recordsLinked to original sources

PubMed2005

Bidirectional labeling and registration scheme for grayscale image segmentation.

In this paper, we introduce a new image segmentation scheme that is based on bidirectional labeling and registration and prove that its segmentation performance is equivalent to that of the conventional watershed segmentation algorithm. The proposed bidirectional labeling and registration scheme, which we refer to as bidirectional labeling and registration scheme (BIDS), involves only linear scans of image pixels. It uses one-dimensional operations rather than the queues that are used in traditional segmentation algorithms, which are two-dimensional problems. BIDS also provides unique labels for individual homogeneous regions. In addition to achieving the same segmentation results, BIDS is four times less computationally complex than the conventional watershed by immersion technique.

Algorithms↗

PubMed2005

Closed-loop cortical control of direction using support vector machines.

Motor neuroprosthetics research has focused on reproducing natural limb motions by correlating firing rates of cortical neurons to continuous movement parameters. We propose an alternative system where specific spatial-temporal spike patterns, emerging in tasks, allow detection of classes of behavior with the aid of sophisticated nonlinear classification algorithms. Specifically, we attempt to examine ensemble activity from motor cortical neurons, not to reproduce the action this neural activity normally precedes, but rather to predict an output supervisory command to potentially control a vehicle. To demonstrate the principle, this design approach was implemented in a discrete directional task taking a small number of motor cortical signals (8-10 single units) fed into a support vector machine (SVM) to produce the commands Left and Right. In this study, rats were placed in a conditioning chamber performing a binary paddle pressing task mimicking the control of a wheelchair turning left or right. Four animal subjects (male Sprague-Dawley rats) were able to use such a brain-machine interface (BMI) with an average accuracy of 78% on their first day of exposure. Additionally, one animal continued to use the interface for three consecutive days with an average accuracy over 90%.

Algorithms↗

PubMed2005

Feature detection in motor cortical spikes by principal component analysis.

Principal component analysis was performed on recorded neural spike trains in rats' motor cortices when rats were involved in real-time control tasks using brain-machine interfaces. The rat with implanted microelectrode array was placed in a conditioning chamber, but freely moving, to decide which one of the two paddles should be activated to shift the cue light to the center. It is found that the principal component feature vectors revealed the importance of individual neurons and windows of time in the decision making process. In addition, one of the first principal components has much higher discriminative capability than others, although it represents only a small percentage of the total variance in the data. Using one to six principal components with a Bayes classifier achieved classification accuracy comparable to that obtained by a more sophisticated high performance support vector classifier.

Action Potentials↗