Biomedical subjects

Jennifer M Jakobi

Publications and source records attributed to Jennifer M Jakobi.

4 recordsLinked to original sources

PubMed2006

Community exercise program for older adults recovering from hip fracture: a pilot study.

Community-based rehabilitative exercise programs might be an effective means to improve functional outcomes for hip-fracture patients. The purpose of this study was to evaluate the effectiveness of a community exercise program (CEP) for older adults recovering from hip fracture. Twenty-five older adults (mean age 80.0 +/- 6.0 years; 24 women; 71 +/- 23 days post-hip fracture) participated in this pilot study (17 exercise, 8 control). The CEP involved functional stepping and lower extremity-strengthening exercises. Control participants received only standard outpatient therapy. Measures of functional mobility, balance confidence, falls efficacy, lower extremity strength, and daily physical activity were evaluated at baseline and at 16 weeks. Improvements for self-reported physical activity, mobility, balance, and knee-extensor strength were observed for the CEP group. This study demonstrated that a CEP is beneficial for community-dwelling older adults post-hip fracture.

Aged↗

PubMed2004

Motor-unit activity differs with load type during a fatiguing contraction.

Despite a similar rate of change in average electromyographic (EMG) activity, previous studies have observed different rates of change in mean arterial pressure, heart rate, perceived exertion, and fluctuations in motor output during the performance of fatiguing contractions that involved different types of loads. To obtain a more direct measure of the motor output from the spinal cord, the purpose of this study was to compare the discharge characteristics of the same motor unit in biceps brachii during the performance of two types of fatiguing contractions. In separate tests with the upper arm vertical and the elbow flexed to 1.57 rad, the seated subjects maintained either a constant upward force at the wrist (force task) or a constant elbow angle (position task) for a prescribed duration. The force and position tasks were performed in random order at a target force equal to 3.5 +/- 2.1% (mean +/- SD) of the maximal voluntary contraction (MVC) force above the recruitment threshold of the isolated motor unit. Each subject maintained the two tasks for an identical duration (161 +/- 96 s) at a mean target force of 22.2 +/- 13.4% MVC (range: 3-49% MVC). The dependent variables included the discharge characteristics of the same motor unit in biceps brachii, fluctuations in motor output (force or acceleration), mean arterial pressure, heart rate, and rating of perceived exertion. Despite similar increases in the amplitude of the averaged EMG (% MVC) for the elbow flexor muscles during both tasks (P = 0.60), the rates of increase in mean arterial pressure (P < 0.001), rating of perceived exertion (P = 0.023), and fluctuations in motor output (P = 0.003) were greater during the position task compared with the force task. Consistent with these differences, mean discharge rate declined at a greater rate during the position task (P = 0.03), and the coefficient of variation for discharge rate increased only during the position task (P = 0.02). Furthermore, more motor units were recruited during the position task compared with the force task (P = 0.01). These findings indicate that despite a comparable net muscle torque, the rate of increase in the motor output from the spinal cord was greater during the position task.

Action Potentials↗

PubMed2004

The 1- to 2-Hz oscillations in muscle force are exacerbated by stress, especially in older adults.

Although force fluctuations during a steady contraction are often heightened in old adults compared with young adults and are enhanced in young adults during the stress response, the mechanisms underlying the augmentation are uncertain. The purpose of the study was to compare the effect of a stressor on the plasma concentrations of selected stress hormones and on the force fluctuations experienced by young and old adults during the performance of a precision grip. Thirty-six men and women (19-86 yr) participated in a protocol that comprised anticipatory (30 min), stressor (15 min), and recovery periods (25 min). The stressor was a series of noxious electrical stimuli applied to the dorsal surface of the left hand. Subjects sustained a pinch-grip force with the right hand at 2% of the maximal voluntary contraction force. The fluctuations in pinch-grip force, the interference electromyogram (EMG) of six muscles, and the spectra for the force and EMG were quantified across the 70-min protocol. The stressor increased the force fluctuations, largely due to an enhancement of the power at 1-2 Hz in the force spectrum (r(2) = 0.46). The effect was greatest for the old adults compared with young and middle-aged adults. The plasma concentrations of the stress hormones (adrenocorticotropin, epinephrine, and norepinephrine) were elevated to similar levels for all three age groups, and the changes were not associated with modulation of the force fluctuations. Furthermore, the heightened EMG activity exhibited by the old adults during all periods was not related to the changes in the force fluctuations or the 1- to 2-Hz force oscillations. The absence of a change in the mean pinch-grip force during the protocol and the lack of an association between elevation of the plasma concentrations for the stress hormones and modulation of the force fluctuations suggest that the enhanced force fluctuations caused by the stressor was due to an increase in the low-frequency output of the spinal motor neurons.

Adolescent↗

PubMed2002

Voluntary muscle activation varies with age and muscle group.

The consistency and the number of attempts required to achieve maximal voluntary muscle activation have not been documented and compared between young and old adults. Furthermore, few studies have contrasted activation between functional pairs of muscle groups, and no study has tested upper limb muscles. The purpose of this study was to measure and compare voluntary muscle activation of the elbow flexors and extensors in young and old men over two separate test sessions. With the method of twitch interpolation to measure activation, six young (24 +/- 1 yr) and six old (83 +/- 4 yr) men performed five maximal voluntary contractions (MVC) during each session for each muscle group. Elbow flexion and extension MVC was less (43 and 47%, respectively) in the old men, yet the best maximal voluntary muscle activation was similar between age groups. However, when all 10 attempts at MVC were compared, the mean activation scores were slightly less (approximately 5%) in the elbow extensors but were approximately 11% less (P < 0.001) in the elbow flexors of old men, compared with young men. During the second session, there was a significant improvement of 13% (P < 0.005) in mean elbow flexor activation in the old men. There were no session differences for either muscle group for the young men. The results indicate that, for aged men, elbow flexor maximal activation is achieved less frequently compared with elbow extensors, and thus mean activation for elbow flexors is less than for elbow extensors. However, if sufficient attempts are provided, the best effort for the old men is not different from that of the young men for either muscle group.

Adult↗