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Jesús Sanz

Publications and source records attributed to Jesús Sanz.

12 recordsLinked to original sources
PubMed2006

Comparison of the volatile composition of wild fennel samples (Foeniculum vulgare Mill.) from central Spain.

Comparison of the volatile composition of fennel (Foeniculum vulgare Mill.) has been carried out using direct thermal desorption (DTD) coupled to gas chromatography-mass spectrometry. Forty-two wild fennel stem samples were collected in two different geographical areas of Central Spain. DTD allowed a high recovery of volatiles from small sample sizes without thermal decomposition. trans-Anethole was the main volatile compound for most cases, although a high variability was found among samples, showing clear phytochemical differences.

Allylbenzene Derivatives↗
PubMed2006

[Recommendations of the Study Group for Metabolic Alterations/Secretariat for the National AIDS Plan (GEAM/SPNS) on the management of metabolic and morphologic alterations in patients with HIV infection].

OBJECTIVE: To provide an update of the metabolic and morphologic alterations in patients infected with HIV with an in-depth analysis of their clinical management and treatment. METHODS: These recommendations were agreed by consensus by a committee of experts in metabolic alterations and HIV patient care, under the auspices of the Secretariat for the National AIDS Plan. To do this, the latest clinical, epidemiological and physiopathological advances described in studies published in the scientific literature and/or presented in congresses were reviewed. RESULTS: The most frequent metabolic alterations in HIV patients and in antiretroviral treatment (ART) are dyslipidemia with an atherogenic profile and alterations in carbohydrate metabolism/insulin resistance. A high prevalence of cardiovascular risk factors, especially smoking, has been described. The same criteria for their management as those used in the general population have been employed, with specific nuances. Diet and exercise should be the first therapeutic recommendation. In patients with dyslipidemia who require drug treatment, statins and/or fibrates are indicated. Glitazones have demonstrated efficacy in the treatment of insulin resistance. The approach to anomalous fat distribution continues to be controversial. The main approaches at present are a switch of ART, reparative surgery, psychological support and lifestyle changes. Lactic acidosis is an infrequent but highly serious complication, and the first step is withdrawal of ART. In bone metabolism alterations, prevention and early detection are essential, especially in children and perimenopausal women. Sexual dysfunction is a frequent problem in both men and women; because the causes are highly varied, treatment should be individualized. CONCLUSIONS: The prevalence of metabolic and morphologic alterations has increased since the introduction of highly active antiretroviral treatment (HAART). Knowledge of the various aspects involved in their diagnosis and treatment is essential for the appropriate care of patients with HIV infection.

Acidosis, Lactic↗
PubMed2005

Analysis of the essential oil composition from the different parts of Eryngiumglaciale Boiss. from Spain.

The essential oil from the different parts (inflorescences, stems + leaves and roots) of Eryngium glaciale Boiss. gathered in Sierra Nevada (Spain) has been extracted by steam distillation and analysed by gas chromatography and gas chromatography coupled to mass spectrometry. Quantitative but not qualitative differences have been found between the analysed parts. The principal compounds from the inflorescences oil were found to be phyllocladene isomer (43.5%), (E)-caryophyllene (15.2%) and valencene (11.5%), while the oil from stems and leaves only showed phyllocladene isomer (41.3%) as main one. The oil from the roots presented phyllocladene isomer (49.4%) and linalool (19.1%) as major constituents. This is the first report on the chemical composition of this species.

Chromatography, Gas↗
PubMed2005

Essential oil composition of the different parts of Eryngium bourgatii Gouan from Spain.

The essential oil extracted from the different parts of Eryngium bourgatii Gouan: stems + leaves (E.b.SL), inflorescences (E.b.I) and roots (E.b.R), have been extracted by steam distillation and analysed by gas chromatography (GC) and gas chromatography coupled to mass spectrometry (GC-MS). Quantitative but not qualitative differences have been found between the analysed parts. The principal compounds from the inflorescences oil were found to be phyllocladene (37.6%) and bicyclogermacrene (15.1%), while the oil from stems and leaves showed phyllocladene (20.4%), gamma-muurolene (11.8%) and (E)-caryophyllene (10.1%) as main ones. The oil from the roots presented gamma-muurolene (15.4%) and phyllocladene (15.0%) as major constituents. It is worth mentioning the presence of a diterpene, phyllocladene, as main compound of the essential oil. This is the first report on the essential oil of this species.

Chromatography, Gas↗
PubMed2005

Characterization of Spanish unifloral honeys by solid phase microextraction and gas chromatography-mass spectrometry.

Volatile compounds have been investigated in unifloral honeys of the most popular types in Spain. A total of 21 eucalyptus samples, 35 rosemary samples, 33 heather samples, and 15 citrus samples were collected in the course of 3 years in different Spanish regions. Samples were analyzed by SPME followed by GC-MS. About 83 compounds were identified; the concentrations of 33 of them were selected to be processed by multivariate analysis. Discriminant analysis allowed correct assignment of most samples: 94% citrus, 92% eucalyptus, 84% heather, and 84% rosemary. As pure reference honeys are not available, a two step data analysis is proposed, selecting the samples most clearly classified in discriminant analysis as "reference samples" to be used in multiple regression to estimate the most representative compounds for each honey type and considering the rest of the samples as of mixed origin.

Gas Chromatography-Mass Spectrometry↗
PubMed2004

Essential oil composition of the leaves and stems of Meum athamanticum Jacq., from Spain.

The essential oil of the leaves and stems of Meum athamanticum Jacq., has been extracted by steam distillation and analysed by gas chromatography (GC) and gas chromatography coupled to mass spectrometry (GC-MS). The monoterpene fraction was predominant while the sesquiterpene one was practically absent. The principal constituents have been identified as (E)-beta-ocimene (29.6%), gamma-terpinene (17.9%), terpinolene (17.0%) and p-cymene (9.7%). Our results show that the chemical composition of the essential oil obtained of the leaves and stems of M. athamanticum from Spain is different to that obtained from plants of Germany, Italy and France.

Apiaceae↗
PubMed2004

Speciation of lipids and humus-like colloidal compounds in a forest soil reclaimed with municipal solid waste compost.

The progressive transformations of lipid and humus-like fractions in soil after massive input (400 Mg ha(-1)) of urban waste have been studied during an 87-week experiment in field plots of a degraded Calcic Regosol in Central Spain. Structural changes in the macromolecular fractions were small when compared with the qualitative and quantitative changes in lipid composition. The intense depletion of the lipid fraction with time and the decrease of the humic acid to fulvic acid ratio were the most significant quantitative indices of the compost transformation in soil. Changes in soil lipid fractions were especially noted in relation to their speciation status and distribution patterns (carbon preference index and relative chain length). Three subfractions were considered: (I) direct extraction with petroleum ether, (II) liquid-liquid extraction after soil treatment with 2 M H3PO4 and (III) after soil treatment with 0.1 M NaOH. Although lipid concentration tends to decrease with time, lipids in the fraction tightly bonded to soil (III) remained qualitatively and quantitatively constant in the course of the field experiment. Gas chromatographic-mass spectrometric analyses showed that the more stable the association of lipid to the soil matrix, the fewer the changes observed in the distribution pattern of the fatty acids during the progressive transformation stages.

Cities↗
PubMed2004

Blood pressure variability and stress management training for essential hypertension.

The purpose of this study was to determine whether stress management training reduces blood pressure (BP) variability in hypertensive patients. Previous literature suggests that cardiovascular risk is not only a function of BP levels, but also of BP variability, and this partially depends on changes induced by the stress of everyday life. The authors reanalyzed data from a previous study of 43 male patients with essential hypertension who were randomly assigned to 2 groups (stress management training and waiting list). Patients in the stress management group lowered their self-measured BP variability significantly from pretreatment to the 4-month follow-up examination, showing a mean reduction of 2.6/1.5 mm Hg in the standard deviation of systolic/diastolic BP (SBP/DBP), and a mean decrease of 1.84/1.59% in the coefficient of variation of SBP/DBP. For SBP, these reductions were significantly greater than those showed by the control group. These results suggest that stress management training is effective in reducing day-to-day BP variability, providing an additional reduction in cardiovascular risk for hypertensive patients.

Cardiovascular Diseases↗
PubMed2002

An empirical comparison of substance and alcohol dependence patterns in the homeless in Madrid (Spain) and Los Angeles (CA, USA).

BACKGROUND: Alcohol and drug use continue to figure heavily in the experience of the contemporary homeless population. The comparison among pattern of use plays a central role in the cross-cultural view of this topic. This article shows the results of comparing the data concerning alcohol and other drug abuse and dependence among the homeless population of Madrid (Spain) and Los Angeles (USA). METHODS: Data come from two studies carried out independently in each city. Both studies used a comparable methodology which included the same inclusion and diagnostics criteria, representative sampling methods and similar diagnostic structured interviews. In the present study, the data from these two studies are combined in a unique database which allows global and item-to-item comparison between the two studies. RESULTS: The results show different sociodemographic profiles for each city. Once controlled for the sociodemographic differences (age, education, current employment status and marital status), the life and 12-month prevalence rates of alcohol and other drug disorders (DSM-III-R) are also different. There are also significant differences in social, emotional and health problems associated with the consumption of alcohol and other drugs. The Madrid and LA samples also present differences in the time patterns of the beginning of the homelessness situation and the onset of alcohol- and drug-related disorders. CONCLUSIONS: The pattern of results is discussed in the light of the differences in both socioeconomic and cultural among Madrid and Los Angeles which might explain, in turn, differences in the homelessness situation as well as in the alcohol and other drug use patterns.

Adolescent↗
PubMedDate not supplied

Rose Bengal-sensitized photooxidation of the dipeptides L-tryptophyl-L-phenylalanine, L-tryptophyl-L-tyrosine and L-tryptophyl-L-tryptophan: kinetics, mechanism and photoproducts.

The Rose Bengal-sensitized photooxidations of the dipeptides l-tryptophyl-l-phenylalanine (Trp-Phe), l-tryptophyl-l-tyrosine (Trp-Tyr) and l-tryptophyl-l-tryptophan (Trp-Trp) have been studied in pH 7 water solution using static photolysis and time-resolved methods. Kinetic results indicate that the tryptophan (Trp) moiety interacts with singlet molecular oxygen (O(2)((1)Delta(g))) both through chemical reaction and through physical quenching, and that the photooxidations can be compared with those of equimolecular mixtures of the corresponding free amino acids, with minimum, if any, influence of the peptide bond on the chemical reaction. This is not a common behavior in other di- and polypeptides of photooxidizable amino acids. The ratio between chemical (k(r)) and overall (k(t)) rate constants for the interaction O(2)((1)Delta(g))-dipeptide indicates that Trp-Phe and Trp-Trp are good candidates to suffer photodynamic action, with k(r)/k(t) values of 0.72 and 0.60, respectively (0.65 for free Trp). In the case of Trp-Tyr, a lower k(r)/k(t) value (0.18) has been found, likely as a result of the high component of physical deactivation of O(2)((1)Delta(g)) by the tyrosine moiety. The analysis of the photooxidation products shows that the main target for O(2)((1)Delta(g)) attack is the Trp group and suggests a much lower accumulation of kynurenine-type products, as compared with free Trp. This is possibly because of the occurrence of another accepted alternative pathway of oxidation that gives rise to 3a-oxidized hydrogenated pyrrolo[2,3-b]indoles.

Dipeptides↗