Biomedical subjects

Jesse T Yen

Publications and source records attributed to Jesse T Yen.

3 recordsLinked to original sources

PubMed2004

Real-time rectilinear 3-D ultrasound using receive mode multiplexing.

In previous work, we developed two generations of a real-time rectilinear volumetric scanner operating at 5 MHz for abdominal, breast, or vascular imaging using a Mills cross two-dimensional (2-D) array and a rectilinear periodic 2-D array. To improve spatial resolution performance and sensitivity, we developed a new design using 4:1 receive mode multiplexing. With 4:1 multiplexing, the new 65,000 element 2-D array has 4 x 256 = 1024 receivers so that 256 receivers can be used on any image line. The two major benefits of using receive mode multiplexing are an increase in receive sensitivity due to a greater number of receive elements, and a decrease in grating lobe and clutter levels due to increased receive element density. Theoretical simulations and analysis show an increase of about 13 dB in sensitivity compared to our previous work. With these encouraging results, a new 65,000 element 5-MHz, 2-D array having 1024 receivers and 169 transmitters was prototyped. In addition, the multiplexer and control circuitry were designed, built, and interfaced with both the transducer and volumetric scanner. Images of tissue-mimicking phantoms and in vivo targets were obtained. Using a spherical cyst phantom, experimental results showed a +12 dB improvement in signal-to-noise ratio and a +6 dB improvement in contrast compared to our previous work.

Adult↗

PubMed2002

Real-time rectilinear volumetric imaging using a periodic array.

Current real-time phased array volumetric scanners use a 2-D array to scan a pyramidal volume comprised of many sector scans stacked in the elevation direction. This scan format is primarily useful for cardiac imaging to avoid interference from the ribs. However, a real-time rectilinear volumetric scan with a wider field-of-view (FOV) close to the transducer could prove more useful for abdominal, breast or vascular imaging. In our previous work, a 94 x 94 Mills cross array operating at 5 MHz was fabricated, and the first real-time rectilinear volumetric images were made using a 2-D array and the Duke real-time 3-D scanner. The FOV for the Mills cross was 30 x 8 x 60 mm. Despite reasonable success with the Mills cross array, the array had limitations of poor off-axis sensitivity and a smaller FOV in one direction. To overcome these limitations, a new rectilinear array containing over 65,500 elements was developed with a periodic geometry to increase the FOV to 30 mm x 30 mm x 60 mm and improve the off-axis sensitivity. Images of tissue-mimicking phantoms and the carotid artery in vivo were obtained. In addition, spectral and color flow Doppler results from a pulsatile flow phantom were obtained.

Cardiac Volume↗

PubMed2002

Real-time rectilinear volumetric imaging.

Current real-time volumetric scanners use a 2-D array to scan a pyramidal volume consisting of many sector scans stacked in the elevation direction. This scan format is primarily useful for cardiac imaging to avoid interference from the ribs. However, a real-time rectilinear volumetric scan with a wider field of view close to the transducer could prove more useful for abdominal, breast, or vascular imaging. In previous work, computer simulations of very sparse array transducer designs in a rectilinear volumetric scanner demonstrated that a Mills cross array showed the best overall performance given current system constraints. Consequently, a 94 x 94 Mills cross array including 372 active channels operating at 5 MHz has been developed on a flexible circuit interconnect. In addition, the beam former delay software and scan converter display software of the Duke volumetric scanner were modified to achieve real-time rectilinear volumetric scanning consisting of a 30-mm x 8-mm x 60-mm scan at a rate of 47 volumes/s. Real-time rectilinear volumetric images were obtained of tissue-mimicking phantoms, showing a spatial resolution of 1 to 2 mm. Images of carotid arteries in normal subjects demonstrated tissue penetration to 6 cm.

Cardiac Volume↗