Biomedical subjects

Ji-wei Luo

Publications and source records attributed to Ji-wei Luo.

4 recordsLinked to original sources

PubMed2006

[Rotational malalignment causing patellofemoral complications after total knee replacement].

OBJECTIVE: To study the rotation of femoral component and tibial component with CT and evaluate the relationship between patellofemoral complications and rotational alignment of the components. METHODS: Thirty patients with isolated patellofemoral complications after total knee arthroplasty were compared with 20 patients with well functioning total knee replacements free of patellofemoral complications. The epicondylar axis and tibial tubercle were used as references on CT scans to quantify the rotational alignment of the femoral and tibial components. RESULTS: Patients with patellofemoral complications had excessive combined (tibial plus femoral) internal component rotation, which was directly proportional to the severity of the patellofemoral complications. Mild combined internal rotation (1 degree-4 degrees) was correlated with patellar and lateral tracking tilting, moderate rotation (3 degrees-8 degrees) with patellar subluxation, and severe rotation (7 degrees-17 degrees) with early patellar dislocation or late patellar prosthesis failure. The control group had combined external rotation of 10 degrees-0 degree. CONCLUSIONS: The direct correlation of combined internal component rotation to the severity of the patellofemoral complication suggests that internal component rotation may be the predominant cause of patellofemoral complications in patients with normal axis alignment. CT scans can be used intraoperatively and postoperatively to determine whether the rotational malalignment is present to require revision of one or both components.

Adult↗

PubMed2006

[Evaluation of perioperative blood loss following total knee arthroplasty].

OBJECTIVE: To evaluate perioperative occult blood loss following total knee arthroplasty (TKA). METHODS: A retrospective analysis of 40 patients undergoing TKA was conducted to calculate the mean blood loss and occult blood loss according to Gross formula. RESULTS: The mean total blood loss was 1538 ml in these cases with occult blood loss of 791 ml. In patients with autologous blood transfusion, the mean total blood loss was 1650 ml with occult blood loss of 786 ml. In patients without autologous blood transfusion, the mean total blood loss was 1370 ml with occult loss of 798 ml. CONCLUSION: TKA often results in large volume of occult blood loss in the perioperative period which can not be fully compensated by autologous blood transfusion, and additional blood supply is needed for maintenance of the circulating volume.

Aged↗

PubMed2003

[Effect of antioxidant vitamins on the exercise performance of rats].

OBJECTIVE: To investigate the effect of antioxidant vitamins (vitamin E and vitamin C) on the exercise performance of rats. METHODS: Fifty male SD rats were randomly divided into control group (C), exhausting exercise control group (E), vitamin E group (M1), vitamin C group (M2) and vitamin E plus vitamin C group (M3). The rats in the exercising groups (E, M1, M2, M3) were propelled for repeated exhausting runs on the treadmill for 4 weeks. RESULTS: Exclusive use of oral vitamin E or in combination with vitamin C significantly improved the body mass, total exercise treadmill length and net mass of rat quadriceps femoris after the 4-week exercise. No difference was noted between the rats taking oral vitamin C or E alone. The rats in M1, M2 and M3 groups had lower malondialdehyde (MDA) and free calcium content in the quadriceps femoris than the control rats, and SOD activities in the quadriceps femoris mitochondria of rats in the former 3 groups were significantly higher than those of the control group. CONCLUSIONS: Vitamin E can protect the mitochondria in the skeletal muscles and improve the exercise performance of rats, the effect of which can be enhanced by vitamin C, but vitamin C alone can not sufficiently achieve the effects.

Animals↗

PubMed2003

[Ultrastructural changes of the skeletal muscle cells of rats subjected to exhausting exercises and the protective effect of vitamin E].

OBJECTIVE: To investigate the ultrastructural changes of the mitochondria in the skeletal muscle cells of rats subjected to repeated exhausting exercises on treadmill and the protective effect of oral vitamin E. METHODS: Thirty male SD rats were randomized into control group (n=10), exhausting exercise group (n=10) and exhausting exercise group with oral vitamin E treatment (n=10), with the latter two groups taking repeated exhausting running exercises on the treadmill in a course of 4 weeks. At the end of the course of exercises, the rats were sacrificed and the quadriceps femoris muscles isolated for observation the ultrastructures of the skeletal muscle cells by transmission electron microscope (TEM). RESULTS: After 4-week exhausting exercises, the myofilaments of the skeletal muscle were seen in disordered alignment, and the mitochondria exhibited abnormal morphological changes of swelling and vacuolar degeneration. In vitamin E-treated rats also undertaking the exercise, the ultrastructures of the skeletal muscle cells were almost normal as compared with the normal control group. CONCLUSION: Vitamin E can protect the function of the skeletal muscle mitochondria of rats taking repeated exhausting exercises.

Animals↗