Biomedical subjects

Jiade Duan

Publications and source records attributed to Jiade Duan.

4 recordsLinked to original sources

PubMed2003

[Benefit of bilateral cochlear implantation on congenital prelingually deafened Chinese-speaking children].

OBJECTIVE: To evaluate the benefit of bilateral cochlear implants (BCIs) in prelingually deafened children on hearing rehabilitation as well as on speech and language development. METHOD: Two cases of congenital profound deaf children, who received unilateral cochlear implantation (CI, MEDEL C40+) on the age of 2 and 7.5, respectively, were performed secondary CI in the contralateral ear on their age of 5 and 9.5, respectively. One year after the secondary CI, the cochlear implant aided hearing threshold and speech discrimination rate were tested for both ears separately and together. The pronounce/speech distinct rate of the BCIs users were evaluated by their parents, surgeon and audiologist. RESULT: In comparison to unilateral aided ear, the mean hearing threshold at the frequency 250-4,000 Hz of the 2 cases with BCIs decreased by 13 dB and 11 dB, respectively. The speech discrimination rate of the BCIs users increased by 9% and 10%, respectively. The speech recognition in noise was improved. And their pronounce/speech distinct was improved. CONCLUSION: BCIs can provide a significant benefit in hearing, speech understanding, language development and pronounce/speech rehabilitation for prelingually deafened children.

Child↗

PubMed2003

[Integrated methods for assessing auditory nerve-auditory pathway integrity].

OBJECTIVE: To evaluate the feasibility and value of integrated methods to assess auditory pathway integrity. METHOD: Twenty-four cases of bilateral profoundly-deafened individuals who were considered as the candidates of cochlear implantation were included in this study. Auditory pathway integrity from these candidates of cochlear implantation were assessed with the integrated methods established by our team, which consist of 5 categories including 1. audiological test; 2. radiological imaging study; 3. ear-canal electric audiometry; 4. response to sound in daily life; and 5. speech development. RESULT: Twenty-three candidates who meet the criteria of auditory nerve-auditory pathway integrity received cochlear implantation with improved hearing and speech development postoperatively. The remainder one of the 24 candidates was diagnosed as bilateral absence of auditory nerve. The fault of cochlear implantation was avoided. CONCLUSION: The integrated methods for assessing auditory pathway integrity is feasible and valuable. Auditory nerve-auditory pathway integrity should be considered and included as one of the most important criteria for cochlear implantation candidate.

Acoustic Stimulation↗

PubMed2002

[Audiological characteristics of auditory neuropathy].

OBJECTIVE: To study the auditory electrophysiological characteristics of the auditory neuropathy. METHODS: Ten patients were diagnosed as auditory neuropathy. The history, pure tone audiometry, stapedial reflex, auditory brainstem response, electrocochleogram, distortion product otoacoustic emission and his contralateral suppression of white noise, middle latency response and slow cortical response were assessed. Five patients were investigated with brain CT or MRI. RESULTS: The patients were of both genders. The average age was 20.3 years old and most of them were teenagers. Nine patients complained of bilaterally hearing impairment, while one patient who did not complain of hearing loss had a tinnitus of both ears. The pure tone audiogram showed a middle or moderate sensorineural hearing loss at low frequencies 0.5 kHz and/or 0.25 kHz in nineteen ears but a normal audiogram in one ear. Stapedial reflex was absent in nineteen ears, and threshold elevated in one ear while his pure tone audiogram revealed an ascending curve. Auditory brainstem response cannot be recorded or only wave V or/and wave I presented. All of the patients were evoked a distortion product OAE, which cannot be suppressed by contralateral white noise. Electrocochleogram demonstrated AP absent or very small amplitude in most ear and the--SP amplitude were 0.595 microV, while they had a normal slow cortical response but except one patient presented normal middle latency response. The findings of CT or MRI were normal. CONCLUSION: The pure tone audiogram could preserve unchanged at early stage of auditory neuropathy, but their stapedial reflex and auditory brainstem response are absent or threshold elevated. The precise pathologic site of this disorder is yet to be defined, but it may locate in the auditory system below brainstem.

Adolescent↗

PubMed2002

[The ECochG in patients with auditory neuropathy].

OBJECTIVE: The purpose of this study was to investigate the ECochG in subjects with auditory neuropathy (AN). METHOD: The ECochG was recorded from ear canal electrode in patients with auditory neuropathy and normal subjects. The difference of their -SP amplitudes was compared. RESULT: The -SP was present in all AN ears and its amplitudes were significantly larger than those in normal subjects (P < 0.01). A low amplitude wave AP was present in 84% AN ears. CONCLUSION: The -SP was present in all AN ears and its amplitudes were larger.

Adolescent↗