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Biomedical subjects

Jianzhong Zhou

Publications and source records attributed to Jianzhong Zhou.

3 recordsLinked to original sources

Aging and the time course of inhibition of return in a static environment.

Age-related differences on the time course of inhibition of return (IOR), a phenomenon that refers to a slowed response time for targets appearing at a previously attended location, were examined in 30 young and 30 elderly adults. Stimulus onset asynchronies (SOAs) between peripheral cues and targets were systematically manipulated on a detection task with a double-cue procedure to capture the onset and offset of IOR. Results show that IOR in elderly people developed 50 ms later as compared to young adults, at an approximately 200 ms cue-target interval. The magnitude of IOR for elderly people was also weaker than that for young adults during short SOAs. Similar magnitude and dissipation of IOR at an approximately 3.5 s cue-target interval during long SOAs were observed for both young and elderly people. Possible reasons underlying the age effects on the time course of IOR and the involvement of temporal processing mechanisms are discussed.

Adult↗

Optimized design of fluorinated polyimide based interleaver.

Statistical optimization method for the design of a fluorinated polyimide wavelength division element for optical communication is proposed. The opitimized device is an interleaver element suitable for dividing over 40 wavelengths in the 1550 nm band. Optimization considers the inherent polarization dependence of fluorinated polyimide based on measurements of the dispersion characteristics and birefringence of fluorinated polyimide film. A 40-wavelength device is designed by use of the proposed technique for a working wavelength of 1550 nm and a wavelength interval of 0.8 nm. The device exhibited a 1-dB passband of 0.5 nm and a 3-dB passband of 0.8 nm, and output wavelength fluctuation due to polarization effects of less than 0.08 nm.

Journal Article↗

Ventricular remodeling by Scutellarein treatment in spontaneously hypertensive rats.

OBJECTIVE: To observe reversal of ventricular remodeling by the protein kinase C inhibitor Scutellarein in spontaneously hypertensive rats (SHRs). METHODS: Twelve SHRs were randomly divided into two groups. Scutellarein and saline (10 mg x kg(-1) x d(-1)) were given by intraperitoneal injection to two groups of rats separately. Systolic blood pressure (SBP) and ventricular weight index (LVW/BW, RVW/BW) were measured. A polarization microscope and an image analyzer system (IAS) were used to observe changes in cardiovascular structure and to count the content of cardiac muscle interstitial collagen. RESULTS: The pathologic changes in the left ventricle in the Scutellarein group rats (SHR(D)) improved to varying degrees, including hypertrophy of the cardiac muscle and collagen volume fraction. CONCLUSION: Scutellarein can reverse ventricular remodeling, improve myocardial stiffness and protect heart cardiac muscle.

Animals↗