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Biomedical subjects

Joanna Tyl

Publications and source records attributed to Joanna Tyl.

3 recordsLinked to original sources

[Rickets prophylaxis under current recommendations].

AIM OF THE STUDY: We analysed the compliance of current recommendations concerning rickets prevention in Poland. MATERIAL AND METHODS: The study group consisted of 65 infants hospitalised because of emergency problems. In each case, the medical history included prophylaxis of rickets and feeding pattern. In most cases (80%) we measured calcium, phosphate, and alkaline phosphatase in the serum. RESULTS: Vitamin D3 was overdosed in 70% of infants. 14% of children were diagnosed as rachitic in outpatient department before hospitalisation, but neither the clinical symptoms nor the laboratory test confirmed the diagnosis. This confirms the observation, that rickets is diagnosed too often, usually on the basis of isolated craniotabes in young infants. CONCLUSION: In the context of changing recommendations for prophylaxis of rickets, we recommend more careful prescribing of vitamin D3 preparations.

Drug Overdose↗

[Antibiotics in lower respiratory tract infection].

THE AIM OF THE STUDY: Comparison of clinical outcome of lower respiratory tract infections in small children treated or not treated with antibiotics. MATERIAL AND METHODS: Eighty seven children aged from 2 months to 5 years admitted to hospital with mild to moderate bronchitis and/or pneumonia were randomly allocated to one of two groups: group A children were treated with antibiotics and group B patients were not. The children remained under close clinical observation. The clinical outcome was considered good if symptoms of the disease decreased after 72 hours. In case of no clinical improvement or worsening, the children from group B received antibiotics and in children from group A antibiotic therapy was changed. RESULTS AND CONCLUSIONS: There were no significant differences between the two groups in the course of the disease, the frequency of pulmonary complications and recurrence during one month of follow-up.

Administration, Oral↗

[Is there a link between chronic chlamydial infection and childhood asthma?].

AIM OF THE STUDY: The paper explores the possible role of chronic chlamydial infection in childhood bronchial asthma. MATERIAL AND METHODS: Sera of 51 asthmatic children and 36 controls were examined by ELISA in search for specific IgA anti-Chlamydia pneumoniae and anti-Chlamydia trachomatis. RESULTS: Results were positive for Chlamydia pneumoniae in 7/51 children with asthma compared with 1/36 controls. Specific IgA anti-Chlamydia trachomatis antibodies were detected in 2/51 patients with asthma and in one of the 36 controls. Infected children, more often than asthmatics without specific chlamydial IgA, suffered from more severe forms of asthma and required multiple-drug therapy, but none of the differences appeared statistically significant.

Adolescent↗