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Biomedical subjects

John D Kayal

Publications and source records attributed to John D Kayal.

2 recordsLinked to original sources

Keratoelastoidosis marginalis.

BACKGROUND: Keratoelastoidosis marginalis is a rare disease that is a variant of solar elastosis. Long-term ultraviolet radiation exposure and chronic trauma secondary to manual labor are considered to be inciting factors. OBJECTIVE: To outline the clinical and histological features of this disorder. METHODS: We report two cases and review the literature. RESULTS: Both patients had persistence of their disease despite multiple topical treatment regimens. CONCLUSION: Keratoelastoidosis marginalis is a chronic and progressive disease that is difficult to treat. The differential includes focal acral hyperkeratosis and acrokeratoelastoidosis.

Female↗

Sporotrichoid cutaneous Mycobacterium avium complex infection.

Mycobacterium avium complex, a common opportunistic pathogen among patients with AIDS, usually manifests as disseminated disease involving the lung, lymph nodes, and gastrointestinal tract. Primary cutaneous infections with M avium complex are extremely rare, and most cutaneous lesions are caused by dissemination. Cutaneous manifestations thus far reported include scaling plaques, crusted ulcers, ecthyma-like lesions, verrucous ulcers, inflammatory nodules, panniculitis, pustular lesions, and draining sinuses. Localized skin involvement resembling sporotrichosis is unusual and to our knowledge has been reported only once in the English-language literature. We describe an additional case of primary cutaneous M avium complex infection manifesting as sporotrichosis-like lesions on a patient with AIDS.

AIDS-Related Opportunistic Infections↗