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Biomedical subjects

John F Federici

Publications and source records attributed to John F Federici.

3 recordsLinked to original sources

Polarized light reflection from strained sinusoidal surfaces.

We propose optical polarization imaging as a minimally invasive technique for measuring the mechanical properties of plastics and soft tissues through their change in reflectance properties with applied strain or force. We suggest that changes in surface roughness are responsible for the linear reflectivity changes with applied stretch or strain. Several aspects of this model are tested, including the dependence on the angle of incidence, the change in scattering and absorption coefficients with strain, and the lateral spatial resolution. The application of the technique to multilayer structures such as skin and competing optical effects such as laser speckle are discussed.

Absorption↗

Measurement of skin stretch via light reflection.

A noninvasive technique for measuring the stretch of skin is described. The technique utilizes changes in the reflectivity of polarized light intensity as a monitor of skin stretch. Measurements of in vitro pigskin and in vivo human skin show that the reflectivity of polarized light intensity increases linearly with stretch. The changes in diffusive reflectivity properties of skin result from the alterations that take place in the roughness across the thickness of the skin layers due to stretch. Conceptually, as the roughness of a layer decreases with stretch, a smoother reflecting media is produced, resulting in a proportional increase in the specular reflection. Results can be easily extended to a real-time stretch analysis of large tissue areas that would be applicable for mapping the stretch of skin.

Animals↗

Terahertz near-field imaging.

A near-field probe is described that enables high spatial resolution imaging with terahertz (THz) pulses. The spatial resolution capabilities of the system lie in the range of few microns and we demonstrate a resolution of 7 microm using broad-banded THz pulses with an intensity maximum near 0.5 THz. We present a study of the performance of the near-field probes in the collection mode configuration and discuss some image properties.

Diagnostic Imaging↗