Biomedical subjects

John G Morris

Publications and source records attributed to John G Morris.

3 recordsLinked to original sources

PubMed2004

Effect of frequency of carbohydrate feedings on recovery and subsequent endurance run.

PURPOSE: This study examined the effect of feeding pattern of a high glycemic index (GI) meal during a short-term recovery on subsequent endurance capacity. METHODS: Eight men ran at 70% .VO2max on a level treadmill for 90 min (T1) on two occasions, followed by 4-h recovery (R) and a further exhaustive run at the same speed (T2). During the R, subjects consumed a prescribed meal with a GI of 77 in either a "gorging" (GOR) or "nibbling" (NIB) intake pattern, providing 1.5 g carbohydrate (CHO) per kilogram body mass. In the GOR trial, the foods were consumed in a single bolus, 20 min after the end of T1. In the NIB trial, the same quantity of food was ingested in three equal portions; the first consumed 20 min after the end of T1 and the remainder at hourly intervals thereafter. RESULTS: The run time during T2 was similar between trials (GOR vs NIB: 68.1 +/- 8.2 vs 66.8 +/- 8.7 min, P > 0.05). However, CHO utilization was lower and fat utilization higher during T2 in the GOR trial compared with the NIB trial (GOR vs NIB: CHO: 94.4 +/- 11.4 vs 117.6 +/- 10.6 g, P < 0.05; FAT: 55.9 +/- 8.0 vs 44 +/- 8.6 g, P < 0.01). CONCLUSIONS: These results suggest that serial consumption of a high GI meal during a 4-h recovery increased the reliance on CHO oxidation for energy provision during a subsequent run when compared with a single feeding. However, there was no difference in the duration of the exhaustive run after the recovery between the GOR and NIB trials.

Adult↗

PubMed2003

A Cartesian coordinate system for human cerebral cortex.

The most commonly used method for specifying the locations of functional areas in the human cerebral cortex is the coordinate system of Talairach and Tournoux (Co-planar Stereotaxic Altas of The Human Brain (1988) Georg Thieme Verlag, Stuttgart). It was designed to locate subcortical nuclei by reference to an axis joining the anterior and posterior commissures. The coordinate system has difficulties, however, when applied to cortical locations: (1) it can be difficult to locate the posterior commissure (PC); (2) the fundamental axis is short, and errors in specifying the axis lead to large errors at the cortical surface; (3) there is no normalisation for brain size. We sought to rectify these problems with a new coordinate system, the Sydney system, in which the fundamental axis runs in the medial sagittal plane from the anterior edge of the corpus callosum to the posterior end of the parieto-occipital sulcus. Normalisation is achieved by dividing all distances by the length of the fundamental axis. Using functionally important points and anatomical landmarks on cadaveric specimens and magnetic resonance images (MRI), three-dimensional coordinates were measured in both the Talairach and Sydney systems. The Sydney system has the following advantages over the Talairach system: (1) the fundamental axis is more than four times longer and is easier to identify; (2) the Sydney system is more precise, in that it reduces the spread of points across the sample; (3) the normalised coordinates allow locations to be compared across individuals, regardless of brain size. We conclude that for the mapping of cortical areas, the Sydney system is potentially an improvement on Talairach's.

Adult↗

PubMed2003

The influence of a 6.5% carbohydrate-electrolyte solution on performance of prolonged intermittent high-intensity running at 30 degrees C.

Nine male student games players consumed either flavoured water (0.1 g carbohydrate, Na+ 6 mmol x l(-1)), a solution containing 6.5% carbohydrate-electrolytes (6.5 g carbohydrate, Na+ 21 mmol x l(-1)) or a taste placebo (Na+ 2 mmol x l(-1)) during an intermittent shuttle test performed on three separate occasions at an ambient temperature of 30 degrees C (dry bulb). The test involved five 15-min sets of repeated cycles of walking and variable speed running, each separated by a 4-min rest (part A of the test), followed by 60 s run/60 s rest until exhaustion (part B of the test). The participants drank 6.5 ml x kg(-1) of fluid as a bolus just before exercise and thereafter 4.5 ml x kg(-1) during every exercise set and rest period (19 min). There was a trial order effect. The total distance completed by the participants was greater in trial 3 (8441 +/- 873 m) than in trial 1 (6839 +/- 512, P < 0.05). This represented a 19% improvement in exercise capacity. However, the trials were performed in a random counterbalanced order and the participants completed 8634 +/- 653 m, 7786 +/- 741 m and 7099 +/- 647 m in the flavoured water (FW), placebo (P) and carbohydrate-electrolyte (CE) trials, respectively (P = 0.08). Sprint performance was not different between the trials but was impaired over time (FW vs P vs CE: set 1, 2.41 +/- 0.02 vs 2.39 +/- 0.03 vs 2.39 +/- 0.03 s; end set, 2.46 +/- 0.03 vs 2.47 +/- 0.03 vs 2.47 +/- 0.02 s; main effect time, P < 0.01). The rate of rise in rectal temperature was greater in the carbohydrate-electrolyte trial (rise in rectal temperature/duration of trial, degrees C x h(-1); FW vs CE, P < 0.05; P vs CE, N.S.). Blood glucose concentrations were higher in the carbohydrate-electrolyte than in the other two trials (FW vs P vs CE:rest, 4.4 +/- 0.1 vs 4.3 +/- 0.1 vs 4.2 +/- 0.1 mmol x l(-1); end of exercise, 5.4 +/- 0.3 vs 6.4 +/- 0.6 vs 7.2 +/- 0.5 mmol x l(-1); main effect trial, P < 0.05; main effect time, P < 0.01). Plasma free fatty acid concentrations at the end of exercise were lower in the carbohydrate-electrolyte trial than in the other two trials (FW vs P vs CE: 0.57 +/- 0.08 vs 0.53 +/- 0.11 vs 0.29 +/- 0.04 mmol x l(-1); interaction, P < 0.01). The correlation between the rate of rise in rectal temperature (degrees C x h(-1)) and the distance completed was -0.91, -0.92 and -0.96 in the flavoured water, placebo and carbohydrate-electrolyte conditions, respectively (P < 0.01). Heart rate, blood pressure, plasma ammonia, blood lactate, plasma volume and rate of perceived exertion were not different between the three fluid trials. Although drinking the carbohydrate-electrolyte solution induced greater metabolic changes than the flavoured water and placebo solutions, it is unlikely that in these unacclimated males carbohydrate availability was a limiting factor in the performance of intermittent running in hot environmental conditions.

Adult↗