Cigarette smoking and erectile dysfunction.
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Case-Control Studies↗
Biomedical subjects
John H Summerson
Publications and source records attributed to John H Summerson.
Differential impact of cardiovascular disease (CVD) risk factor clustering on CVD and renal disease among African-American and white patients with type 2 diabetes mellitus.
OBJECTIVES: To determine if clustering of cardiovascular disease (CVD) risk factors has a differential impact on CVD and renal disease among African Americans compared to Whites with type 2 diabetes DESIGN: Cross-sectional. METHODS: Prevalent CVD, macroalbuminuria, and CVD risk factors were measured in 323 African-American and White adult patients with type 2 diabetes. CVD risk factors were dichotomized according to standard guidelines. Data were analyzed by race according to the presence of any 3 or more CVD risk factors. RESULTS: Despite a similar prevalence of hypertension, the prevalence of macroalbuminuria in the presence of 3 or more CVD risk factors tended to be higher among African Americans compared to Whites (28.9% vs 13.6%, P = 0.05). The presence of 3+ CVD risk factors was associated with an odds ratio (OR) of 2.5 (P = 0.001, 95% CI, 1.44-4.27) for macroalbuminuria in African Americans compared to an OR of 1.4 (P = 0.25, 95% CI, 0.78-2.53) in Whites. The race/3+ CVD risk factors interaction was statistically significant (P = 0.007). Conversely, the presence of 3+ risk factors was associated with an OR of 1.6 (P = 0.019, 95% CI, 1.08-2.28) for CVD in Whites compared to an OR of 0.8 (P = .287, 95% CI, 0.54-1.20) in African Americans. The prevalence of any CVD in the presence of 3+ risk factors was 61% and 49% in Whites and African Americans respectively (P = .217). The race/3+ CVD risk factors interaction was statistically significant (P = 0.029). CONCLUSIONS: These findings suggest that among persons with diabetes, a clustering of 3+ CVD risk factors is more predictive for renal disease among African Americans, and more predictive for CVD in Whites. Further research should clarify the impact of CVD risk factor clustering on the incidence of vascular disease among African Americans and Whites with type 2 diabetes.
Black or African American↗
Hospitalizations and outcomes for diabetic gastroparesis in North Carolina.
BACKGROUND: Population-based data to assess the extent of gastroparesis in the diabetic population are scarce. We examined the demographic and clinical characteristics associated with hospital admissions for diabetic gastroparesis in North Carolina. METHODS: Data from the 1998 North Carolina Hospital Discharge database were abstracted from records in which gastroparesis and diabetes mellitus were listed as simultaneous diagnoses. RESULTS: There were 1476 discharges meeting our criteria, with total charges of $11,378,446 over 7850 total hospital days. Most patients were female (65.8%), > or = 45 years of age (54.5%), and had Medicare as the primary payer (52.1%). While most of these patients were admitted under emergency or urgent circumstances, the vast majority had routine discharges. CONCLUSION: Despite some limitations, these data indicate that diabetic gastroparesis is not uncommon, but can be treated effectively.
Diabetes Complications↗