Sentinel lymph node biopsy in breast cancer: the lymphatic is as important as the lymph node.
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Biomedical subjects
Publications and source records attributed to John Harman.
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AIM: To demonstrate a seasonal variation in the detection of breast cancer in women diagnosed at St Marks Breast Centre, Auckland. METHODS: Data on women diagnosed with breast cancer at St Marks Breast Centre from January 1992 till December 2001 were obtained from the computerised database. RESULTS: A total of 1760 women were diagnosed with breast cancer; 1584 were referred by their general practitioner and 176 self referred. The peak incidence of seasonal diagnosis was in spring (September, October, November) with 521 cases. The lowest incidence was in summer (December, January, February) with 375 cases. These findings were consistent annually from 1992 to 2001. CONCLUSIONS: There is a seasonal variation in the incidence of breast cancer similar to that noted in other studies. Our findings suggest that temporal factors and possible behavioural patterns may have a role in this seasonal variation.
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AIMS: To determine whether specific pulsed electrostatic fields, or electrotrichogenesis (ETG), could potentially prevent or reduce hair loss in patients undergoing adjuvant cyclophosphamide, methotrexate and 5-fluorouracil (CMF) chemotherapy for breast cancer. METHODS: Thirteen women were followed during their adjuvant ETG and chemotherapy treatment to determine the efficacy of ETG. All patients were treated for 12 min, twice weekly with a pulsed electrostatic field. Quantitative hair loss was measured by photographic assessment, and manual hair count. Quality of life assessment was conducted at the end of the study. RESULTS: Twelve out of 13 participants had good hair retention throughout the chemotherapy period and afterwards. There were no reported side effects attributable to ETG. CONCLUSIONS: This study shows encouraging results in an area where no other appropriate treatment is available Reducing alopecia, secondary to chemotherapy has the potential to increase CMF treatment compliance, enhance patient self-esteem, and improve overall quality of life during this stressful period.
Aggressive fibromatosis is a rare, locally aggressive disease. It constitutes 0.3% of all solid tumors, but the tumor is rarely seen in the breast, particularly without pectoral muscle and fascial involvement. The etiology is unknown, but an association with Gardner's syndrome has been described. Clinical and imaging findings simulate breast carcinoma. A case in a 53-year-old female patient is reported.
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