Biomedical subjects

John McManus

Publications and source records attributed to John McManus.

8 recordsLinked to original sources

PubMed2006

The art and science of surge: experience from Israel and the U.S. military.

In a disaster or mass casualty incident, health care resources may be exceeded and systems may be challenged by unusual requirements. These resources may include pharmaceuticals, supplies, and equipment as well as certain types of academic and administrative expertise. New agencies and decision makers may need to work together in an unfamiliar environment. Furthermore, large numbers of casualties needing treatment, newer therapies required to care for these casualties, and increased workforce and space available for these casualties all contribute to what is often referred to as "surge." Surge capacity in emergency care can be described in technical, scientific terms that are measured by numbers and benchmarks (e.g., beds, patients, and medications) or can take on a more conceptual and abstract form (e.g., decisions, authority, and responsibility). The former may be referred to as the "science" of surge, whereas the latter, an equal if not more important component of surge systems that is more conceptual and abstract, can be considered the "art" of surge. The experiences from Israel and the U.S. military may serve to educate colleagues who may be required to respond or react to an event that taxes the current health care system. This report presents concrete examples of surge capacity strategies used by both Israel and the U.S. military and provides solutions that may be applied to other health care systems when faced with similar situations.

Civil Defense↗

PubMed2006

The science of surge: detection and situational awareness.

As part of the broader "science of surge" consensus initiative sponsored by Academic Emergency Medicine, this report addresses the issues of detection and situational awareness as they relate to surge in the practice of emergency medicine. The purpose of this report, and the breakout group that contributed to its content, was to provide emergency physicians and other stakeholders in the emergency medicine community a sense of direction as they plan, prepare for, and respond to surge in their practice.

Awareness↗

PubMed2005

Vesicants.

Vesicants (or blister agents) are cytotoxic alkylating compounds, which are chemical agents sometimes collectively known as mustard gas or simply as mustard. Other blister agents are nitrogen mustard; sulfur mustard; lewisite, a vesicant that contains arsenic; and phosgene oxime, a halogenated oxime that possesses different properties and toxicity from the other agents. This article discusses history, toxicity, clinical presentation, and common treatment for vesicants.

Chemical Warfare↗

PubMed2005

A survey of Oregon emergency physicians to assess mandatory reporting knowledge and reporting patterns regarding intoxicated drivers in the state of Oregon.

OBJECTIVES: To assess emergency physician reporting patterns in Oregon before and after the passage of a mandatory intoxicated driving reporting law. METHODS: A one-page survey was mailed to 504 emergency physicians in Oregon in April 2004. Data on reporting frequency were collected using a four-point ordinal scale regarding motor vehicle crash-involved drivers (MIDs) and intoxicated persons attempting to drive away from the emergency department (DAEDs). Paired observations were assessed for a stated increase in reporting activity following passage of the law using the Wilcoxon signed-rank test. Associations of postlaw reporting and demographic and knowledge factors were sought using Spearman rank correlation analysis. RESULTS: Of the 504 surveys mailed, 298 (59%) were adequate for analysis. Many respondents (57%) were already aware of the law. Most (92%) agreed that physicians should be mandated to report some crimes. MIDs were always reported by 18% of physicians before the law and by 47% afterward, whereas DAEDs were always reported by 56% of physicians before the law and by 69% afterward. Emergency medicine-trained physicians, higher emergency department census, and increased years of experience were associated with a significantly higher increase in reporting pattern after passage of the law for both MIDs and DAEDs. CONCLUSIONS: Although 44% of responding emergency physicians in Oregon were unaware of a mandated reporting law for intoxicated drivers presenting to the ED, most physicians stated an increase in their reporting practice.

Alcoholic Intoxication↗

PubMed2005

Informed consent and ethical issues in military medical research.

Informed consent in military research shares many of the same fundamental principles and regulations that govern civilian biomedical research. In fact, much of modern research ethics is grounded in events that occurred in the context of war or government-sponsored research. Despite these similarities and common origins, research in the military has additional requirements designed to preserve service members' informed consent rights. The special nature of the superior-subordinate relationship in the military necessitates careful protections to avoid perceptions of coercion or undue influence on a military subject. Additionally, current legal and regulatory requirements for advanced informed consent significantly restrict the flexibility of the military to conduct research using waiver of consent. This has implications on the ability of the nation to develop effective medical treatments for the global war on terrorism. Nevertheless, work is under way to realign defense research policy with the norms of civilian biomedical practice. Future directions include the adoption of waivers for military emergency research, and the cautious introduction of human subject studies on the battlefield. This paper discusses historical background, regulatory differences, and concerns and challenges of some of these regulatory differences for research personnel that apply to informed consent and waiver of said informed consent for emergency research conducted by the U.S. military.

Government Regulation↗

PubMedDate not supplied

Radial pulse character relationships to systolic blood pressure and trauma outcomes.

BACKGROUND: Patient measurements that do not require monitoring equipment may be the only way to evaluate casualties in austere conditions to determine treatment and transport priority. Objective. To test the hypothesis that palpable pulse characteristics in the radial artery would estimate systolic blood pressure (SBP) and predict outcome in trauma patients. METHODS: Data were analyzed from the medical records of 342 trauma patients ranging from 18 to 50 years of age. Prehospital data were collected by helicopter emergency medical personnel at the scene of the injury. Based on radial pulse character, patients were divided into normal (n = 313) and weak (n = 29) groups. Those whose medical records did not describe pulse characters were not considered. Differences in SBP, mortality, and medical interventions between the radial-pulse-character groups were evaluated. RESULTS: The SBP taken at the scene was a mean of 26 mm Hg lower in those patients with weak radial pulse characters (102 mm Hg versus 128 mm Hg). Similarly, the lowest mean SBPs recorded in the field between the normal- and weak-pulse-character groups were 112 mm Hg and 99 mm Hg, respectively. Patient mortality increased with weak pulse character such that the mortality rats were 3% for the normal-pulse-character group and 29% for the weak-pulse-character-group (odds ratio = 15.2). CONCLUSIONS: These preliminary data suggest that a weak radial pulse may be an acceptable method for initial rapid evaluation of trauma patients. This simple and rapid method of pulse evaluation should be considered for the triage of trauma patients in field conditions with limited instrumentation.

Adolescent↗

PubMedDate not supplied

Use of ultrasonography to avoid an unnecessary procedure in the prehospital combat environment: a case report.

The role of ultrasonography in the prehospital combat setting has become a useful tool for triage, diagnosis, and treatment. Recent literature has demonstrated that ultrasonography has a greater sensitivity and specificity than clinical examination and plain radiography for pneumothorax detection in trauma patients, particularly small pneumothoraces. This becomes especially critical in austere and remote environments. Although many pneumothoraces are initially considered non-life-threatening, austere and combat environments possess additional risks of limited supplies, multiple casualties, and prolonged evacuation times that may potentially increase the morbidity of these injuries. This case report discusses the role of ultrasonography in pneumothorax detection in the prehospital combat environment.

Adult↗

PubMedDate not supplied

A case series describing thermal injury resulting from zeolite use for hemorrhage control in combat operations.

Four cases are presented to illustrate cutaneous burns sustained with the use of zeolite in the treatment of major hemorrhage secondary to combat wounds. Zeolite, a microporous crystalline aluminosilicate granular hemostatic agent, can cause secondary thermal injuries through an exothermic reaction that is likely related to the absorption of free fluid at the hemorrhage site. Understanding of this process may help both military and civilian EMS personnel avoid or minimize secondary thermal injury while still benefiting from zeolite's hemostatic capabilities.

Adult↗