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Biomedical subjects

John R Graham

Publications and source records attributed to John R Graham.

24 records · Page 2Linked to original sources

Mental health aspects of Arab-Israeli adolescents from polygamous versus monogamous families.

The authors considered the mental health consequences of polygamy in a sample of 101 Arab Muslim adolescents (19 from polygamous and 82 from monogamous families) at Juarish (Ramla), Israel. The respondents completed the Self-Esteem Scale (SE; M. Rosenberg, 1979), the Brief Symptom Inventory (BSI; L. Derogatis & N. Melsavados, 1983; L. Derogatis & P. Spencer, 1982), and the McMaster Family Assessment Device (FAD; N. B. Epstein, M. N. Baldwin, & D. S. Bishop, 1983). The respondents from polygamous families had lower SE scores, statistically significant higher scores in 2 BSI dimensions, higher scores in all other BSI dimensions, and higher levels of self-reported family dysfunction. The respondents from polygamous families reported lower levels of socioeconomic status, academic achievement, and parental academic attainment. Those variables may have had a more direct impact on mental health than did parental marital status. The data also indicated that perceived family functioning was the best predictor of mental health.

Analysis of Variance↗

Identifying faking bad on the Minnesota Multiphasic Personality Inventory-Adolescent with Mexican adolescents.

This study examined the extent to which the validity scales of the Minnesota Multiphasic Personality Inventory-Adolescent identified Mexican adolescents who were instructed to fake bad. Validity scales data were used to differentiate between nonclinical adolescents instructed to fake bad and both clinical and nonclinical adolescents who received standard instructions. Participants were 59 male and 87 female Mexican high school students and 59 male and 87 female Mexican adolescents from clinical settings. This is the first study onfaking with adolescents in Mexico. The F, Fl, and F2 Scales and the F-K index discriminated adequately between the three different groups. Results were similar to those previously reportedfor adults and adolescents in Mexico and the United States. High positive and negative predictive powers and overall hit rates were obtained in this study. Higher cut scores were needed to discriminate between the groups of girls than between the groups of boys.

Adolescent↗

The appropriateness of the MMPI-2 K correction.

The extent to which the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) K scale serves as a suppressor variable that influences the validity of clinical scale scores was examined using 274 male and 425 female outpatients from a community mental health center and 105 male and 247 female clients from a university psychological clinic. Hierarchical regression analyses were performed with MMPI-2 K scale scores and clinical scale scores as predictors and therapist ratings as criteria. In most cases, the K scale did not act as a suppressor Optimal K weights were different from the traditional K corrections. In most instances, there were no significant differences between correlations of therapist ratings with K-corrected and uncorrected clinical scale scores. The results do not support the K scale as a suppressor variable in these settings, although additional research is needed in settings where higher levels of defensiveness are common.

Adult↗

Assessing general maladjustment with the MMPI-2.

The validities of 7 MMPI-2 (Butcher, Graham, Ben-Porath, Tellegen, & Kaemmer, 2001) measures of general maladjustment were compared using a composite criterion measure based on self-reported symptom severity and clinicians' ratings of symptom severity and level of functioning. Participants were 274 male and 425 female clients at a community mental health center and 105 male and 247 female clients at a university psychological clinic. All MMPI-2 measures were significantly related to the composite criterion measure for both male and female clients in both settings. The mean score on 8 clinical scales (M8) consistently was the best indicator of maladjustment. Although other MMPI-2 measures sometimes added significantly to the variance accounted for in the criterion measure, increments were small and probably not clinically meaningful. However, M8 added significantly and meaningfully to each of the other MMPI-2 measures in predicting maladjustment. Implications for using the MMPI-2 to assess general maladjustment in outpatient mental health settings are discussed.

Adjustment Disorders↗

A controlled study of a serotonin reuptake blocker, zimelidine, in the treatment of chronic pain.

Zimelidine inhibits the central neuronal reuptake of serotonin and has undergone clinical evaluation as an antidepressant. Twenty patients with chronic pain of non-malignant origin (mean duration 15.8 years) were entered into a double blind cross-over study of the analgesic efficacy of zimelidine and placebo. The duration of each treatment phase was 6 weeks and there was a comprehensive assessment of each patient prior to the commencement and at the completion of the study, during a brief period of hospitalisation. Zimelidine was superior (P less than 0.05) to placebo with respect to pain relief based on a global assessment (by the clinical investigators) performed at the completion of each treatment phase. However, there was no significant difference in analgesic efficacy between the zimelidine and placebo treatment phases based on the following criteria: (a) changes in the minimum effective blood concentration of pethidine necessary to provide pain relief in each patient, measured during a pethidine infusion of 1.67 mg/min for 60 min; (b) changes in pain scores estimated by patients using the visual analogue pain scale (VAPS); (c) changes in patients' estimates of pain intensity associated with various daily activities. Significant pain relief was apparent within 2-3 days in those patients who had a beneficial effect, which contrasts with the documented 3-4 weeks for maximal antidepressant effects. The results of this study suggest that serotonin reuptake blockers do not provide consistent pain relief in patients with chronic pain, but may contribute an analgesic effect in the treatment of some patients.

Adult↗

Pricing drugs.

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Aged↗