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Jolanta Zyczkowska

Publications and source records attributed to Jolanta Zyczkowska.

6 recordsLinked to original sources
PubMed2006

The prevalence of cardiovascular risk factors among centenarians is low: risk factors in centenarians.

BACKGROUND: The presence of major cardiovascular risk factors was investigated in a group of centenarians. METHODS: The following risk factors: sex, smoking, overweight, diabetes, hypertension and hypercholesterolemia were analysed in 93 centenarians and compared with data obtained from 90 individuals age 40-60 years. RESULTS: Smoking, overweight and hypercholesterolemia were found statistically more often in a younger population, whereas hypertension was diagnosed more frequently in centenarians. No or one risk factor were found in 55.4% of centenarians and in 14.2% of younger subjects. CONCLUSIONS: Centenarians are characterized by a much better cardiovascular risk profile than middle-aged individuals. This indicates that longevity is related to low cardiovascular risk.

Adult↗
PubMed2006

[Comprehensive geriatric assessment in hospitalized patients aged 80 years and more].

Comprehensive geriatric assessment during hospitalization, taking into account the specificity of geriatric patients could be used both in acute and long-term care. We analyzed 63 patients aged at least 80 years, born on odd days and hospitalized at the Department of Internal Medicine and Geriatrics, University Hospital, Kraków. We examined patients using Geriatric Assessment Chart which consisted of Barthel Index (used to determinate motor activity), MMSE, GDS (Geriatric Depression Scale), abbreviated Tinetti Test, Waterlow Index (used to determine the risk of pressure sore development), delirium risk factors scale, and social evaluation. The data were analyzed according to sex, marital status, level of mood, and residence status (free living or institutionalized). The mean age of 47 women and 16 men was 85.0 +/- 4.34 years. Dementia was been found in 60% of examined patients. Depression (usually mild) was encountered in 55.4%. Motor activity was moderately to severely impaired in the entire group, with high level of risk of falls and development of pressure sores. Thirteen per cent of the patients have been admitted with already developed ulcers. The results suggest the need for the comprehensive geriatric assessment both in hospitalized patients and in post-hospital phase of care.

Accidental Falls↗
PubMed2005

[Hematologic parameters in Polish centenarians].

We undertook this study to characterize the haematological indices in centenarian subjects who should be an excellent group to study the mechanisms of physiological aging. This study is a part of the Polish Centenarians Program co-ordinated by the International Institute of Molecular and Cell Biology in Warsaw. We examined 89 subjects aged 100 to 111 (14 males and 75 females). Mean values of all haematological parameters were within the normal range in females. In males, haemoglobin level (Hb), red blood cell count (RBC) and hematocrit (Hct) were slightly lower than WHO references (12.7 +/- 1.3 g/dl, 4.10 +/- 0.48 M/ml and 38.4 +/- 3.8%, respectively). However, anaemia was more frequent in females than in males (57.1% vs 29.1%, p < 0.05). In females with anaemia there was a tendency to decrease its severity with age. In the oldest group (aged 105-111 years) Hb and Hct had a tendency for lower values vs the youngest group (100-101 years) (10.1 +/- 1.8 g/dl vs 11.6 +/- 0.1 g/dl, p = 0.067 and 30.9 +/- 5.0% vs 35.0 +/- 0.3%, p = 0.067). Additionally, in the youngest group there were three females with severe anaemia (Hb < 9.0 g/dl) whereas in the oldest group all females with anaemia had Hb above 11.0 g/dl. In males the analysis was not undertaken because of small group of studied subjects. In conclusion, anaemia seems to be a relatively common problem in studied centenarians. Severe anaemia seems to be an eliminating factor in centenarian women.

Age Factors↗
PubMed2005

[Morphology of neutrophils in centarians].

Recently, centenarians are involved in many research programs as they are believed to represent so-called successful aging. The aim of the study was to characterize morphological alterations observed in neutrophils from their peripheral blood. The study involved 40 centenarians (group B--34 females and 6 males) as well as 40 young healthy subjects aged 20-30 years (group K--35 females and 5 males). The study is a part of the Polish Centanarians Program coordinated by the International Institute of Molecular and Cell Biology in Warsaw. In this study, the morphometry of neutrophils from blood smear was performed in all studied subjects. Additionally, in centenarians, the relationship between observed alteration and serum level of vitamin B12 and folic acid was analyzed. Both the mean size of granulocytes and the mean value of neutrophil lobe counts were higher in group B vs group K (15.5 +/- 0.6 mm and 13.9 +/- 0.7 mm; p<0.0001 and 4.01 +/- 0.7 and 3.2 +/- 0.2; p<0.0001). Chromatin chips and toxic granules in cytoplasm were observed more often in centenarians as well (39/40 vs 20/40--p<0.0001 and 40/40 vs. 23/40--p<0.0001; respectively). In centenarians, there was no relationship between the presence of morphological alterations in granulocytes and the serum level of vitamin B12 and folic acid. In conclusion, morphological alterations were very common in studied centenarians. Detailed analysis of biochemical parameters and clinical status is necessary to answer the question about their pathomechanism.

Adult↗
PubMed2003

Electrocardiogram in centenarians.

BACKGROUND: Electrocardiographic abnormalities in the very elderly have not yet been fully assessed. AIM: To evaluate ECG recordings obtained from centenarians. METHODS: ECG tracings recorded at place of residence of 35 subjects aged 100-112 years (mean 101.7 years) were examined using the Minnesota code. RESULTS: Entirely normal ECG recordings were found in 5.7% of centenarians. The most frequently encountered abnormalities included leftward QRS axis deviation (45.7%), abnormal T wave morphology (42.9%), ST segment depression (34.3%), extrasystolic beats (28.6%), left anterior haemiblock (25.7%) and first degree atrio-ventricular block (17.1%). Other, less frequently present abnormalities, included Q wave or QS complex, atrial fibrillation, right or left bundle branch block, left ventricular hypertrophy or low QRS voltage. CONCLUSIONS: In the majority of centenarians ECG shows numerous but usually benign abnormalities. Only very few centenarians have entirely normal ECG.

Aged↗