Biomedical subjects

Jonathan S Abramowitz

Publications and source records attributed to Jonathan S Abramowitz.

At least 19 recordsLinked to original sources

PubMed2006

The cognitive mediation of thought-control strategies.

Research suggests that people use various strategies to control their normally occurring intrusive thoughts. Strategies that involve worrying about the thought and self punishment appear to be associated with certain forms of psychopathology, such as obsessive-compulsive (OC) symptoms. The present study sought to examine whether dysfunctional beliefs associated with OC symptoms (e.g., beliefs that intrusive thoughts are highly significant) underlie the use of such thought control strategies. Ninety-three non-clinical participants completed self-report questionnaires measuring cognitive variables, thought-control strategies, and OC symptoms. Analyses revealed that overestimates of threat and responsibility, beliefs about the significance and need to control intrusions, the need for perfection and certainty, and scrupulosity were associated with the use of punishment, but not worry thought control strategies. These cognitive phenomena also mediated the relationship between OC symptoms and the use of punishment as a thought-control strategy. Results are discussed in terms of cognitive models of OC symptoms and their implications for cognitive-behavioral therapy.

Adult↗

PubMed2006

New parenthood as a risk factor for the development of obsessional problems.

Research on emotional disturbance during pregnancy and the postpartum period has focused primarily on mood disorders and psychosis, yet preliminary evidence suggests that early parenthood is also associated with an increased risk for the development and exacerbation of obsessional problems. In this article we describe the nature of "postpartum obsessive-compulsive disorder" (ppOCD) and present a cognitive-behavioural model to account for these signs and symptoms. The model outlines features of early parenthood that might increase vulnerability to ppOCD and proposes a conceptual framework similar to that described in cognitive-behavioural models of OCD in general. The empirical status of the model described herein is discussed, along with suggestions for future research and implications for treatment.

Cognition↗

PubMed2006

The cognitive mediation of obsessive-compulsive symptoms: a longitudinal study.

Contemporary cognitive models of obsessive-compulsive disorder (OCD) posit that OC symptoms arise from negative interpretations of intrusive thoughts, which are derived from trait-like dysfunctional assumptions ("obsessive beliefs;" e.g., concerning overestimates of responsibility). Although correlational studies suggest that obsessive beliefs, negative interpretations of intrusions, and OC symptoms are interrelated, prospective studies evaluating the directional hypotheses implied in the cognitive model are lacking. In the present longitudinal study, 76 first time expecting parents were followed through the postpartum. Results indicated that the tendency to negatively interpret the presence and meaning of unwanted intrusive infant-related thoughts early in the postpartum period (3-4 weeks) mediated the relationship between pre-childbirth obsessive-beliefs and late postpartum (12 weeks) OC symptoms. Results are discussed in terms of their theoretical and treatment implications.

Adult↗

PubMed2006

Parents' perceptions of pharmacological and cognitive-behavioral treatments for childhood anxiety disorders.

Cognitive-behavioral therapy (CBT) and pharmacotherapy are the most well-established treatments for childhood anxiety disorders. This study examined how parents (N=71) seeking treatment for their child's anxiety disorder perceive the acceptability, believability, and effectiveness of these treatments. While both treatments were perceived favorably, CBT was rated as more acceptable, believable, and effective in the short- and long-term. Children's treatment history influenced parents' perceptions of pharmacotherapy, with parents of children with no treatment history perceiving medication treatment as less acceptable and believable than parents of children with a history of medication alone or in combination with behavior therapy. No effect of treatment history was found for perceptions of CBT. Significant positive correlations emerged between parents' perceived acceptance and believability for pharmacotherapy and child age and level of dysfunction due to their child's anxiety, respectively. The level of the child's anxiety was not significantly correlated with parents' perceptions of either CBT or pharmacotherapy. Our results suggest that parents of anxious children prefer CBT to medication for the treatment of their child's anxiety disorder. Directions for future research are discussed.

Adolescent↗

PubMed2006

An experimental analysis of hypochondriasis.

Hypochondriasis (HC) involves preoccupation with fears of having a serious medical illness based on the misinterpretation of benign bodily perturbations. Individuals with HC also perform behaviors such as checking and reassurance-seeking presumably to reduce health-related fears. Experimental behavioral analyses of HC symptoms, however, are lacking. In the present study, 27 patients with HC were exposed to personally relevant health-related stimuli under one of two conditions: (a) subsequently performing safety-seeking behaviors (e.g., checking) (n=14) or (b) subsequently being instructed not to perform such behaviors (n=13). In both groups, subjective anxiety and urges to perform safety behaviors were monitored for 1h. Results indicated that exposure to the personally relevant health trigger provoked anxiety and urges to perform safety behaviors. For patients who performed such behaviors, these feelings were reduced. For patients who did not, a more gradual reduction of anxiety and urges was observed. Findings are discussed in terms of the conceptualization and treatment of HC behavior, and are relevant to HC's possible relationship to panic and obsessive-compulsive disorder.

Adolescent↗

PubMed2006

Psychometric properties and construct validity of the Obsessive-Compulsive Inventory--Revised: Replication and extension with a clinical sample.

The present study examined the psychometric properties and construct validity of the Obsessive-Compulsive Inventory--Revised (OCI-R) with the aim of replicating and extending previous findings, and addressing limitations of previous investigations. Individuals with OCD (n = 167) and other anxiety disorders (n = 155) completed the OCI-R, measures of OCD and related symptom severity, and measures of cognitive variables associated with OCD symptoms. Results indicate that the OCI-R is a psychometrically sound and valid measure of OCD and its various symptom presentations. Confirmatory factor analysis confirmed a six-factor solution. The instrument also evidenced good convergent validity, and performed well in discriminating OCD from other anxiety disorders. Theoretically consistent patterns of associations between OCI-R symptom-based subscales and OCD-related cognitive variables were found, and five of the six OCI-R subscales corresponded closely to identified OCD symptom dimensions. The OCI-R is recommended as an empirically validated instrument that can be used in a range of clinical and research settings for research on OCD.

Adolescent↗

PubMed2006

Scrupulosity in patients with obsessive-compulsive disorder: relationship to clinical and cognitive phenomena.

Scrupulosity is often encountered among individuals with obsessive-compulsive disorder (OCD), yet relatively few studies have examined this particular symptom presentation. Using a large sample of OCD patients, the present investigation examined (a) the relationship between religiosity and scrupulosity, (b) the association between scrupulosity and the severity of OCD, anxiety, and depressive symptoms, and (c) the connection between scrupulosity and cognitive domains related to OCD. Scrupulosity was correlated with obsessional symptoms and several cognitive domains of OCD, including beliefs about the importance of, and need to control intrusive thoughts, an inflated sense of responsibility, and moral thought-action fusion. These results are examined in terms of cognitive behavioral conceptualizations of OCD and the treatment implications of these findings are discussed.

Adult↗

PubMed2006

A magnetic resonance spectroscopy investigation of obsessive-compulsive disorder and anxiety.

The aim of the current study was to use proton magnetic resonance spectroscopy (MRS) to investigate potential irregularities in neurochemical compounds in obsessive-compulsive disorder (OCD) and the extent to which these irregularities are related to state anxiety. Single voxel MRS was used to image the head of the caudate nucleus (HOC) and orbitofrontal white matter (OFWM) bilaterally in adult patients with OCD and a control group. The results indicated that patients with OCD had increased levels of a combined measure of glutamate and glutamine (Glx/Cr) and N-acetyl-l-aspartic acid (NAA/Cr) relative to creatine in the right OFWM and reduced levels of myo-inositol relative to creatine (mI/Cr) in the HOC bilaterally. Correlational analyses indicated that Glx/Cr in the OFWM was related to OCD symptoms, while mI/Cr in the HOC was related to trait and/or state anxiety. Reanalysis of the significant group differences controlling for state anxiety symptoms erased three of the four group differences. These results are discussed in context of the methodological difficulties facing this area of research.

Adult↗

PubMed2006

Hypochondriasis: conceptualization, treatment, and relationship to obsessive-compulsive disorder.

Once considered exclusively as a problem secondary to other mental dis-orders (ie, mood disorders), HC is now known to occur quite often as a pri-mary diagnosis. A frequent drain on medical resources, patients who have HC can be viewed as suffering essentially from an anxiety disorder in which intense fear is focused on the possibility that they might be seriously physically ill or that such illness is imminent. The processes that contribute to the development and maintenance of such health anxiety consist largely of beliefs, assumptions, and behavioral responses that, although internally consistent with the perception of health-related threat, are erroneous and highly maladaptive in that they prevent the correction of erroneous perceptions of threat. There is growing evidence that this conceptualization leads to effective reduction in HC symptoms through cognitive-behavioral and pharmacologic treatments. By far the main obstacle to successful treatment of HC is the patient's reluctance to view the problem as anything other than physical. The authors have found, however, that patients appreciate their care providers showing a genuine understanding of their concerns and taking the time to offer a logical, coherent explanation and rationale for the need for psychological and psychiatric services.

Attitude to Health↗

PubMed2006

The psychological treatment of obsessive-compulsive disorder.

The psychological treatment of obsessive-compulsive disorder (OCD) with exposure and response prevention (ERP) methods is one of the great success stories within the field of mental health. Within the span of about 20 years, the prognosis for individuals with OCD has changed from poor to very good as a result of the development of ERP. This success not with-standing, the procedures are far from perfect because a substantial minority of patients still either refuse treatment, drop out prematurely, or fail to benefit. I begin this article with a review of the development of ERP from early animal research on avoidance learning conducted during the 1950s. Next, I discuss the mechanisms of ERP. The bulk of the article reviews the treatment-outcome literature on ERP for OCD and includes comparisons with cognitive therapy--the "new kid on the block" with respect to psychological treatments for OCD.

Cognitive Behavioral Therapy↗

PubMed2006

Listening to hypochondriasis and hearing health anxiety.

Although hypochondriasis is categorized as a somatoform disorder in the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition--Text Revision (DSM-IV-TR) due to excessive focus on bodily symptoms for at least 6 months, a contemporary conceptualization suggests that hypochondriasis represents an intense form of health anxiety. This article discusses the clinical presentation of hypochondriasis, etiological underpinnings and multiple maintaining factors, including physiological, cognitive and behavioral components. A cognitive-behavioral model of hypochondriasis as health anxiety and the empirically supported treatment based on the model are articulated. Future directions and informational resources are provided for both clinicians and patients.

Anxiety Disorders↗

PubMed2005

The role of cognitive factors in the pathogenesis of obsessive-compulsive symptoms: a prospective study.

Cognitive models of obsessive-compulsive disorder (OCD) posit that specific kinds of dysfunctional beliefs (e.g., pertaining to responsibility and the significance of intrusive thoughts) underlie the development of this disorder. The present study was designed to prospectively evaluate whether dysfunctional beliefs thought to underlie OCD act as a specific vulnerability factor in the pathogenesis of obsessive-compulsive symptomatology. Eighty-five individuals were prospectively followed over a period of time thought to be associated with an increased onset of OCD symptoms -- childbirth and the postpartum. The majority of these new mothers and fathers experienced intrusive infant-related thoughts and performed neutralizing behaviors similar to, but less severe than, those observed in OCD. Scores on a measure of dysfunctional beliefs thought to underlie OCD predicted the development of obsessive-compulsive symptoms after controlling for pre-existing OCD symptoms, anxiety, and depression. Dysfunctional beliefs also predicted the severity of checking, washing, and obsessional OCD symptom dimensions, but not neutralizing, ordering, or hoarding symptom dimensions. These data provide evidence for specific dysfunctional beliefs as risk factors in the development of some types of OCD symptoms.

Adolescent↗

PubMed2005

Disgust sensitivity and obsessive-compulsive symptoms in a non-clinical sample.

Disgust sensitivity has been posited to play a role in the etiology and/or maintenance of obsessive-compulsive disorder (OCD); however, results of studies in this area have been mixed. We examined the relationship between specific domains of disgust sensitivity and specific OCD symptom patterns. One thousand and five undergraduate volunteers completed an internet battery of questionnaires including measures of OCD symptoms, depression, anxiety, and disgust sensitivity. Results indicated that even when controlling for depression and anxiety, several OCD symptom groups (checking, ordering, and washing) were associated with disgust sensitivity. Analysis of residuals, in which we controlled for every other OCD and disgust sensitivity domain for each paired comparison, indicated that the clearest relationship was between washing symptoms of OCD and disgust sensitivity toward hygiene-related stimuli. Examination of these items, however, raises questions about whether commonly accepted measures of disgust sensitivity might confound disgust with other forms of aversion. We discuss possible strategies for clarifying the degree to which fear and disgust are involved in OCD symptoms.

Adolescent↗

PubMed2005

Dimensionality of somatic complaints: factor structure and psychometric properties of the Self-Rating Anxiety Scale.

Somatic complaints are often key features of anxiety pathology. Although most measures of anxiety symptoms capture somatic complaints to some degree, the Self-Rating Anxiety Scale (SAS) was developed primarily as a measure of somatic symptoms associated with anxiety responding. We evaluated the psychometric properties and factor structure of the SAS in two large undergraduate samples who completed the SAS and measures of anxiety and depression. Exploratory factor analysis revealed four lower-order SAS factors in both samples: (1) anxiety and panic; (2) vestibular sensations; (3) somatic control; and, (4) gastrointestinal/muscular sensations. The SAS demonstrated good reliability in both samples, and the correlations between the SAS factors and other anxiety variables provide supportive evidence for convergent validity, though evidence for discriminant validity was limited. The strengths and limitations of the SAS are offered as well as the implications of our findings for the nature and assessment of somatic complaints in anxiety disorders.

Adult↗

PubMed2005

Do dysfunctional beliefs play a role in all types of obsessive-compulsive disorder?

Some but not all models of obsessive-compulsive disorder (OCD) emphasize the role of dysfunctional beliefs in the etiology and maintenance of this disorder. Clinical observations suggest that some OCD patients have prominent dysfunctional beliefs associated with their obsessions and compulsions, while other patients do not show this pattern. It is possible that dysfunctional beliefs play a role in only a subgroup of cases of OCD and, by extension, that different models might apply to different subtypes of the disorder. To examine this issue, patients with OCD (N = 244) completed measures of dysfunctional OC-related beliefs, along with measures of OC symptoms and demographics. These measures were also completed by three comparison groups; anxious (N = 103), student (N = 284), and community (N = 86) controls. Cluster analysis revealed two OCD clusters: low versus high scores on beliefs (OC-low, OC-high). Belief scores for OC-low were in the range of scores for the comparison groups, which were all significantly lower than those of OC-high. Thus, a cluster of OCD patients was identified who did not have elevated scores on measures of dysfunctional beliefs. OC-low and OC-high did not differ on some OC measures (contamination, checking, grooming), but OC-high had higher scores on measures of harming obsessions. These results are consistent with the view that dysfunctional beliefs may play a role in only some types of OCD.

Adult↗

PubMed2005

The expression of anger and its relationship to symptoms and cognitions in obsessive-compulsive disorder.

We compared the association between obsessive-compulsive disorder (OCD) and the expression of anger in a sample of 71 patients and 71 college students. Some authors [Rubenstein et al., J Anxiety Disord 1995;9:1-9] have proposed that anger and hostility underlie the symptoms of OCD; however, there has been little empirical study of this relationship. One recent study [Whiteside and Abramowitz, Cog Therapy Res 2004;28:259-268] with college undergraduates found that the association between OCD symptoms and anger was attributable to depressive symptoms. In the present study, we compared the expression of anger in a sample of patients diagnosed with OCD and nonclinical volunteers. Consistent with the previous study, we found increased levels of anger in patients with OCD as compared to control participants; however, these differences could be attributed to between-group differences in general distress. These results were discussed within the framework of the cognitive theory of OCD.

Adult↗

PubMed2005

The Yale-Brown Obsessive Compulsive Scale: factor analysis, construct validity, and suggestions for refinement.

The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) is widely acknowledged as the gold standard measure of obsessive-compulsive disorder (OCD) symptom severity. Despite its popularity, a number of questions remain regarding the Y-BOCS' psychometric properties including: (a) whether obsessional and compulsive symptoms contribute independently to global OCD severity and (b) whether the Y-BOCS subscales are valid with respect to other measures of OCD. We examined these issues in a sample of 100 patients with a diagnosis of OCD. While our confirmatory factor analyses failed to reproduce any previously reported models of the Y-BOCS factor structure, exploratory factor analysis indicated a two-factor solution that assessed symptom severity (i.e., time, distress, and interference from obsessions and compulsions) as separate from resistance and control of obsessions and compulsions. In contrast to the Resistance/Control Subscale, the Severity Subscale demonstrated good psychometric properties and construct validity. Based on our findings we recommend revisions to scoring the Y-BOCS.

Adult↗

PubMed2005

Is obsessive-compulsive disorder a disturbance of security motivation? Comment on Szechtman and Woody (2004).

H. Szechtman and E. Woody (2004) proposed that obsessive-compulsive disorder (OCD) is caused by a malfunctioning brain security motivation system. In the current article, the authors' review of the model suggests that it is limited in the following ways: (a) It is built on a selective review of the empirical literature, (b) it offers no explanation for many important OCD phenomena, (c) it fails to distinguish OCD from generalized anxiety disorder, (d) some of the model's predictions are ambiguous or unfalsifiable, and (e) other predictions are refuted by previously published research. Models proposing that OCD is caused by a single dysfunctional mechanism, such as the security motivation model, have difficulty explaining the complexity and heterogeneity of OCD.

Animals↗