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Biomedical subjects

Jonathan T Stewart

Publications and source records attributed to Jonathan T Stewart.

11 recordsLinked to original sources
PubMed2006

The frontal/subcortical dementias: common dementing illnesses associated with prominent and disturbing behavioral changes.

Although the most common cause of dementia is Alzheimer's disease, many other common dementing illnesses in the elderly affect the frontal cortex and associated subcortical structures and present with very different symptoms. In general, these illnesses are not detected with typical bedside screening or with conventional dementia assessment tools, such as the Mini Mental State Exam. These illnesses are associated with prominent and disturbing behavioral changes, as well as difficulties with "higher-order" cognitive functions, such as planning and judgment. Common causes of frontal/subcortical dementia include vascular dementia, frontotemporal dementia, alcoholic dementia, dementia due to AIDS, and a number of movement disorders. Familiarity with this clinical picture is essential for recognition, diagnosis, and management of these illnesses, and for working with families and caregivers.

Alzheimer Disease↗
PubMed2004

Capgras syndrome related to diazepam treatment.

Capgras syndrome, the delusion that identical-appearing impostors have replaced familiar people, is an unusual phenomenon usually seen in schizophrenia or dementia. We recently cared for a 78 year old man who seemed to develop Capgras syndrome as an adverse reaction to diazepam. An iatrogenic cause should be considered in the differential diagnosis of any new delusion, including Capgras syndrome.

Aged↗
PubMed2003

Dysphagia associated with risperidone therapy.

Dysphagia is occasionally reported in patients taking neuroleptic agents, although the newer, "atypical" neuroleptics are generally believed to be associated with fewer neurologic side effects. We report a 76-year-old man who developed radiographically confirmed dysphagia when treated with risperidone; the dysphagia resolved when risperidone was withdrawn. Clinicians should be aware of the potential for this dangerous but highly reversible problem.

Aged↗
PubMed2003

Defining diffuse Lewy body disease. Tetrad of symptoms distinguishes illness from other dementias.

It is an ageless principle in medicine that physicians cannot diagnose and treat an illness they do not recognize. In the past two decades, we have come to recognize the classic clinical picture of diffuse Lewy body disease. Once primary care physicians understand this challenging disorder, they are in an ideal position to identify and manage it. As with many dementing illnesses and other medical conditions, diffuse Lewy body disease is not curable, but much can be done to improve the quality of life of patients and their family.

Alzheimer Disease↗