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Biomedical subjects

José Loureiro

Publications and source records attributed to José Loureiro.

6 recordsLinked to original sources

Intraventricular thrombi with systemic embolization: two clinical cases.

Ventricular thrombi are a frequent complication of dilated cardiomyopathy and acute myocardial infarction, with variable risk of embolization according to the clinical setting and thrombus morphology. The authors report two cases of patients admitted on the same day for acute myocardial infarction and dilated cardiomyopathy respectively, with high embolic risk left ventricular thrombi that embolized to the lower limbs after admission. Echocardiography, considered the gold standard diagnostic tool for intraventricular thrombi, is also the mainstay of embolic risk evaluation, for characterizing their size, mobility and echostructure. In the absence of evidence-based guidelines, management options--anticoagulation therapy, thrombolysis or thrombectomy--must be decided according to each specific case, taking account of embolic, bleeding and surgical risk.

Adult↗

Pulmonary embolism associated with a large tricuspid-related mass.

The case of a 43-year-old man with diabetes and alcoholism admitted to the emergency room with shock, fever, pleuritic chest pain and systemic symptoms is presented. Laboratory tests revealed anemia, leukocytosis, thrombocytopenia, high sedimentation rate and D-dimers, hypoxemia and hypocapnea. He also had sinus tachycardia, rSR' in V1 and an opacity on the periphery of the right pulmonary field. Blood and urine cultures were negative, as were serological markers. The echocardiogram showed a large mass adhering to the tricuspid valve, suggestive of myxoma. The patient underwent surgery, and anatomopathological examination of the mass showed it to be a bacterial vegetation, with no agent isolated. It is pointed out that differential diagnosis is difficult between a myxoma with systemic symptomatology associated with a possible pulmonary embolism, and tricuspid endocarditis with negative blood culture associated with a septic pulmonary embolism, which turned out to be the diagnosis in this patient.

Adult↗

Free floating thrombus in right atrium and pulmonary thromboembolism.

The authors describe a case of a patient with inoperable bladder cancer, who was admitted with syncope and arterial hypotension. After examination, an echocardiogram was requested, which showed a free-floating thrombus in the right atrium and dilatation of the right chambers. A diagnosis of pulmonary embolism was made, and heparin was started. The patient's clinical status worsened, with development of severe pulmonary hypertension due to the presence of large thrombi in the right and left pulmonary arteries. Despite a recent hemorrhagic event related to the bladder cancer, thrombolytic therapy was begun with improvement of the patient. The final echocardiogram was almost normal, without pulmonary hypertension and no dilatation of the right chambers.

Aged↗

Simultaneous catheterization of the coronary arteries in the treatment of chronic total occlusions.

Chronic total occlusions present technical challenges to the interventional cardiologist, and are accompanied by an increased propensity for complications. We present an argument for the routine use of simultaneous bilateral coronary angiography to help define the lesion and optimize the therapeutic approach. Eight selected cases of CTO were revascularized using this technique resulting in immediate procedural success, devoid of complications, in all cases.

Adult↗