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Biomedical subjects

Ju-ying Zhang

Publications and source records attributed to Ju-ying Zhang.

2 recordsLinked to original sources

[Analysis of ordinal repeated measures data using generalized estimating equation].

OBJECTIVE: To explore the application of the generalized estimating equation in the ordinal repeated measures data and hence provide methodology reference for the analysis of repeated measures data in the clinical trials. METHODS: An example was illustrated by modeling generalized estimating equation using the GENMOD command in comparison with the independent logistic regression. RESULTS: All parameters and their standard error were estimated, so every factor could be dealt with intuitive estimation of parameter. The standard errors of coefficients in generalized estimating equation are generally greater than that in independent logistic regression. CONCLUSION: Generalized estimating equation can solve the correlation between the dependent data by using working correlation matrix, and it can control strata correlation, repeated measures factor and other confounding factors effectively, so generalized estimating equation provides an effective method for the ordinal repeated measures data.

Clinical Trials as Topic↗

[Survey of behaviors and knowledge about HIV/AIDS among intravenous drug users at a city in Sichuan Province].

OBJECTIVE: To understand high risk behaviors related to HIV/AIDS and the intravenous drug users' knowledge about HIV/AIDS. METHODS: Forty-eight intravenous drug users (IDUs) were interviewed by using questionnaires. RESULTS: The survey showed that 75% of the subjects were male, 83.3% of their educational levels were below junior middle school, and most of them lived in cities(83.0%), having no occupation or having special occupation. The age at the beginning of drug use was 11 years old, the ages in cities were earlier than those in the countryside (F = 3.898, P = 0.029). For the reasons of using drug, 58.1% of IDUs did so through curiosity; 57.1% of IDUs had ever shared the syringes and needles with others, 62.5% of them shared with fixed people. 79.5% of the IDUs had casual sex partners, and 68.75% had multiple sex partners, but only less than 40% of them used condoms when having sex with casual partner. CONCLUSION: There are many high risk factors related to the IDUs' drug addiction and sex behaviors which can facilitate the transmission of HIV.

Acquired Immunodeficiency Syndrome↗