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Biomedical subjects

Juan J Sancho

Publications and source records attributed to Juan J Sancho.

2 recordsLinked to original sources

[Surgical treatment of recurrent secondary hyperparathyroidism].

INTRODUCTION: Secondary renal hyperparathyroidism (SHPT) affects nearly all patients on regular hemodialysis. Between 5% and 10% will need surgery to control the disease. Despite a meticulous technique, the rate of recurrent/persistent hyperparathyroidism after surgery remains between 2% and 12%. PATIENTS AND METHOD: We reviewed the reoperations of 7 patients with recurrent or persistent SHPT from a series of 56 patients, 3 of which were referred from other units for treatment of recurrence. Subtotal parathyroidectomy (ST-PTX) was performed in 51 patients and total parathyroidectomy with autograft (TPTX-AT) was performed in the remaining 5 patients. RESULTS: Seven patients underwent reoperation for recurrent SHPT, 1 of them twice (8 reinterventions in 56 patients). In 2 patients only 3 parathyroid glands were removed at the first intervention and recurrence was due to the presence of a fourth gland. In 4 patients, ST-PTX was performed and recurrence was due to a remnant hyperplasic area in 1 and to a fifth gland in 3. Recurrence in the patient with a TPTX-AT was to due to cervical parathyromatosis. All the patients with recurrence had a positive preoperative Tc-MIBI scintigraphy and the computed tomography/magnetic resonance examination was highly useful for anatomical localization of the lesion and for planning the surgical approach.

Adult↗

[Computer-assisted clinical decision support systems].

This review deals with the historical evolution and methodological basis of computerized medical decision support tools. It also reviews the verification, validation and impact evaluation methods of these systems. The acceptability of them from the health professionals depends on the pro-activity and usefulness of the systems, between other factors. The clinical impact evaluation methods are described in deep detail and the Hunt et al review of 1998 is updated.

Decision Making, Computer-Assisted↗