Biomedical subjects
Publications and source records attributed to Julian Newell.
In this article, the author clarifies the definition of sepsis, severe sepsis and septic shock, describes the physiological changes that occur and the initial treatment used to improve patient outcome, and examines the concept of early goal directed therapy (EGDT).
This article outlines the causes, signs and symptoms of systemic inflammatory response syndrome (SIRS), sepsis, severe sepsis and septic shock, the implications and available treatments. The article also highlights a campaign to reduce the incidence of sepsis and reflects on efforts to reduce healthcare-associated infections.