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Biomedical subjects

Julie Harper

Publications and source records attributed to Julie Harper.

2 recordsLinked to original sources

The use of topical retinoids for inflammatory acne: a review of the pharmacoeconomic considerations.

Few pharmacoeconomic studies exist regarding the use of topical retinoids for inflammatory acne vulgaris. Those pharmacoeconomic studies that do exist predictably involve new entrants (topical tazarotene in various formulations). The use of topical retinoids in combination with antimicrobial agents constitutes cost-effective therapy for inflammatory acne. The growing U.S. trend toward use of isotretinoin for less-severe forms of acne instead of topical retinoid-based combination therapy is problematic from clinical and cost perspectives. More pharmacoeconomic studies that consider the importance of compliance are necessary for clinicians and managed care professionals to make informed choices about the treatment of inflammatory acne.

Acne Vulgaris↗

Paraneoplastic dermatoses.

Skin manifestations of systemic disease and malignancy are protean. The recognition of a potentially paraneoplastic dermatosis as such must prompt an investigation for occult malignancy. Lack of familiarity with cutaneous clues of internal malignancy may delay diagnosis and treatment of cancer. It is important to consider a paraneoplastic process in the differential diagnosis of a number of eruptive and treatment-resistant dermatoses. These dermatoses may be the first sign of an occult neoplasm. Their recognition may assist in cancer detection and the swift induction of appropriate therapy.

Diagnosis, Differential↗