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Biomedical subjects

Julie K Timins

Publications and source records attributed to Julie K Timins.

6 recordsLinked to original sources
PubMed2004

Current issues in hormone replacement therapy.

Initially used to treat the vasomotor and vaginal symptoms of menopause, hormone replacement therapy (HRT) appeared to have many unexpected beneficial effects in early observational trials. It was hailed as a deterrent of atherosclerosis, osteoporosis, cognitive impairment, and Alzheimer disease. While its salutary effects on bone mass were substantiated, randomized clinical trials noted an increased risk of breast cancer, coronary artery disease, and thromboembolism, and raised doubts about the efficacy of HRT in improving quality of life. This article summarizes the literature and discusses current recommendations on the use of HRT.

Alzheimer Disease↗
PubMed2003

Radiological terrorism.

A radiological terrorist attack on the United States is a possibility. This could involve the dispersal of radioactive material by an attack on a nuclear facility, deployment of a radiation dispersal device, or, less likely, detonation of a nuclear weapon. To decrease our vulnerability to this type of threat, the medical community should have a basic understanding of radiation hazards and their medical management, and it should be prepared to interact with appropriate federal agencies to facilitate the employment of emergency response plans.

Decontamination↗
PubMedDate not supplied

Controversies in mammography.

Concerns about screening mammography include questions of efficacy, high recall rates, false positives, and age at which to institute annual screening. Annual screening mammography can decrease breast cancer mortality by 45% in women over fifty and 23% in women between forty and fifty years of age. Patient recall rates and accuracy of interpretation vary among radiologists. Suggestions for improving accuracy of mammographic interpretation include continuing education with emphasis on quality of interpretation, computer-assisted detection, double reading, increased volume per reader, and performance-related skills testing. Having fewer radiologists reading more mammograms may result in decreased patient access to mammography services. Poor reimbursement for mammography and high prevalence of breast cancer-related litigation are disincentives for radiologists to provide mammography services; these issues must be addressed to ensure patient access to mammography. The public must be educated so that reasonable expectations on the benefits and limitations of mammography will develop.

Breast Neoplasms↗