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Biomedical subjects

Julie Ross

Publications and source records attributed to Julie Ross.

4 recordsLinked to original sources

Dogs acquire food preferences from interacting with recently fed conspecifics.

Social transmission of food preferences has been documented in many species including humans, rodents, and birds. In the current experiment, 12 pairs of domestic dogs (Canis familiaris) were utilized. Within each pair, one dog (the demonstrator) was fed dry dog food flavored with either basil or thyme. The second dog (the observer) interacted with one demonstrator for 10 min before being given an equal amount of both flavored foods. Observers exhibited a significant preference for the flavored diet consumed by their demonstrators, indicating that dogs, like rats, prefer foods smelled on a conspecific's breath.

Animals↗

Lineage-specific activators affect beta-globin locus chromatin in multipotent hematopoietic progenitors.

During development, the regulated expression of tissue-specific genes can be preceded by their potentiation, that is, by chromatin activation in progenitor cells. For example, the human beta-like globin genes are potentiated in a gene- and developmental-specific manner in hematopoietic progenitors. Developmental regulation of human beta-gene expression in erythroid cells is mostly determined by transcriptional activators; however, it is not clear how gene-specific potentiation is set in hematopoietic progenitors. Using human and transgenic multipotent hematopoietic progenitors, we demonstrate that human beta-globin locus activation is characterized by TBP, NF-E2, CBP and BRG1 recruitment at both the Locus Control Region and human beta-gene promoter. Our results further indicate that in hematopoietic progenitors, EKLF influences chromatin organization at the human beta-globin locus and is instrumental for human beta-gene potentiation. Thus, we show that lineage-specific transcriptional activators expressed at basal levels in progenitor cells can participate in gene potentiation.

Animals↗

Screening risks for intimate partner violence and primary care settings: implications for future abuse.

Most health care intervention models for intimate partner violence (IPV) are crisis driven and targeted to survivors of injury following episodes of physical violence. Knowledge about anticipatory and preventive approaches with women who are at risk for abuse is scarce, limiting professionals' ability to respond fully and effectively to this problem. This paper describes a retrospective, practice-based research study of social work interventions in two hospital-based primary care practices. A total of 431 female patients completed a self-administered questionnaire developed for the early detection of IPV risk factors during routine health care visits. The study showed surprisingly high rates of multiple risk markers in an urban primary care population whose medical presentations ordinarily would not raise provider suspicion about abuse. Findings confirmed the willingness of primary care populations to freely partake in routine screening and support the value of early identification and intervention with populations at risk. Practice implications are discussed.

Adolescent↗

An evidence-based domestic violence education program for internal medicine residents.

BACKGROUND: Domestic violence (DV) is prevalent but often unrecognized, and it is a challenge to teach. This article presents an evidence-based DV education program for medical residents and incorporates it into a women's medicine curriculum. DESCRIPTION: An initial 3-hr seminar included video and case discussion, literature review, and role play. Participants then actively screened patients for 2 weeks and returned for a follow-up discussion session. The program was well received. EVALUATION: Six to 12 months after the intervention, key features questions were utilized to measure ability to correctly suspect DV in patient situations. Residents who had not attended the program served as controls. Three of the 8 questions were suspicious for abuse. Fifty-four percent of respondents in the intervention group correctly suspected DV in at least 2 out of 3 questions compared with 20% of controls (p = .02). CONCLUSIONS: An evidence-based DV education program was well received and helped correctly suspect DV.

Curriculum↗