Biomedical subjects

Jun Mizuno

Publications and source records attributed to Jun Mizuno.

2 recordsLinked to original sources

PubMed2005

High efficiency electrochemical immuno sensors using 3D comb electrodes.

To realize highly sensitive electrochemical immunoassays, a micro-fabricated three-dimensional (3D) electrode was fabricated and applied to enzyme immuno assay based on production of a redox species. The dimensions of the electrodes are 10 microm in width and 30 microm in height, with 20 microm spacing in between, and the 30 pairs of anode and cathode electrodes made up a single sensor. This structure lead to enhancement of the electrochemical reaction, nearly 100% of trap ratio of redox species. It can be applied to highly sensitive enzyme immuno sensing based on p-aminophenylphosphate (PAPP). Applicability of this technique to the immuno assay for one of the clinical diagnostic marker proteins (alpha-fetoprotein; AFP) from 6 to 500 ng/mL was demonstrated.

Biological Assay↗

PubMed2003

Exceeding the classical capacity limit in a quantum optical channel.

The amount of information transmissible through a communications channel is determined by the noise characteristics of the channel and by the quantities of available transmission resources. In classical information theory, the amount of transmissible information can be increased twice at most when the transmission resource is doubled for fixed noise characteristics. In quantum information theory, however, the amount of information transmitted can increase even more than twice. We present a proof-of-principle demonstration of this superadditivity of classical capacity of a quantum channel by using the ternary symmetric states of a single photon, and by event selection from a weak coherent light source. We also show how the superadditive coding gain, even in a small code length, can boost the communication performance of the conventional coding technique.

Journal Article↗