Biomedical subjects

Jun Ye

Publications and source records attributed to Jun Ye.

57 records · Page 4Linked to original sources

PubMed2002

[Neonatal screening for congenital adrenal hyperplasia in Shanghai areas].

OBJECTIVE: To investigate the incidence of congenital adrenal hyperplasia (CAH) in Shanghai areas by a neonatal screening program. METHODS: Heel prick blood samples were collected from 50 600 newborns in 50 maternal and child health care hospitals and maternity hospitals 72 hours after their birth and adsorbed onto standard filter paper for determining 17-hydroxyprogesterone (17-OHP) by enzyme linked-immunosorbent assay (ELISA). RESULTS: Level of 17-OHP was significantly increased in eight cases of the 50 600 newborns, three cases of whom with established CAH with hyponatremia, hyperkalemia and hypertestosteronemia duo to 21-hydroxylase deficiency, and other five cases with high level 17-OHP due to preterm delivery. CONCLUSIONS: Determining 17-OHP level on dried blood spotted filter paper is a reliable and practical approach for CAH mass screening in neonates. The incidence of CAH in Shanghai areas was 5.93 per 100 000 newborns (3/50 600).

17-alpha-Hydroxyprogesterone↗

PubMed2002

[Analysis of pathogenic relations between dental caries and periodontitis].

OBJECTIVE: In order to search the cause of dental caries and periodontitis. METHODS: Selected 70 patients with severe chronic periodontitis (CP group) and 50 patients with caries sensitivity (CS group) in clinical adults of oral medicine (18 to 50-year-old) during 1 year. Parameters of oral hygiene, caries and periodontitis were recorded in the typical groups of CP and CS. RESULTS: The patients of CP group had rare caries, DFS in the groups of CP and CS was 1.46+/-2.60 and 17.32+/-7.55 respectively(p<0.001),while the patients of CS group had relative periodontal health indeed, CPTNI in CS and CP groups were 0.98+/-0.63 and 3.24+/-0.62 respectively (p<0.001), and the number of missing teeth was 1.90+/-3.34 and 1.10+/-1.85 respectively(p>0.05). 3 patients(only 2.4%)confirmed the parameters of caries sensitive as well as severe periodontitis. CONCLUSION: The correlating pathogenesis of caries and periodontitis seems to have antiagonism tendency. The ecological connection and bacterial interaction are worthy of further study.

English Abstract↗

PubMed2002

[Juvenile periodontitis survey in 9548 middle school students at Huangpu District in Shanghai].

OBJECTIVE: 9548 middle school students from 11-19 age at Huangpu District in Shanghai were investigated to study the prevalence of juvenile periodontitis(JP). The purpose of the present study was to discover JP at early stage and make correct diagnosis, so the patients can be treated on time. METHODS: From January 2001 to April 2001, debris index(DI), calculus index(CI), sulcus bleeding index(SBI) and community periodontal index for treatment needs (CPITN) were examined in each student. RESULTS: In 9548 investigated (4739 males and 4809 females), prevalence of JP was 0.76%, the ratio of males to females was 1:1.03 (P<0.05). With aging, the detectable rate of gingival bleeding and calculus was increasing, the prevalence of JP was also increasing. CONCLUSION: Since the new classification system of periodontal disease was established, the above cases are worth reevaluating. We should also enhance oral hygiene of the young people.

English Abstract↗