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Biomedical subjects

Jung Chul Choi

Publications and source records attributed to Jung Chul Choi.

7 recordsLinked to original sources

Eruptive pseudoangiomatosis.

Eruptive pseudoangiomatosis (EPA) is a rare, self-limiting exanthem, which is known to occur primarily in children. It is characterized by an eruption of distinctive erythematous angioma-like papules often surrounded by a pale halo, with histological findings distinct from that of true angiomas. We describe three women with angioma-like papules. The biopsy specimens from them showed a unique histological appearance consisting of dilated dermal blood vessels with plump endothelial cell and perivascular lymphocytes. On the basis of the clinical and histological findings, we present the adult cases of eruptive pseudoangiomatosis and their etiology.

Aged↗

Calcinosis cutis of the fingertip associated with Raynaud's phenomenon.

Cutaneous calcification may be divided into four major categories: (i) dystrophic; (ii) metastatic; (iii) idiopathic; and (iv) iatrogenic. Dystrophic calcification is the most common type of calcinosis cutis and is associated with a variety of diseases. It most notably occurs in connective tissue diseases. Diffuse and limited cutaneous systemic sclerosis is an example of connective tissue diseases that frequently show calcinosis. We experienced a case of fingertip calcinosis cutis associated with Raynaud's phenomenon. The patient had no previous trauma, skin lesion or systemic connective tissue disease. We propose that calcinosis cutis of the fingertip may result from chronic ischemic injury caused by Raynaud's phenomenon.

Adult↗

Plasma cell cheilitis treated with intralesional injection of corticosteroids.

Plasma cell cheilitis is an idiopathic, benign, inflammatory condition characterized by a dense band-like infiltrate of plasma cells in the oral mucosa. In addition to the lips, the disease can affect the penis, vulva, buccal mucosa, palate, gingiva, tongue, epiglottis, and larynx. Some authors have shown the effectiveness of topical or intralesional corticosteroids; however, there have been many reports describing poor therapeutic responses to topical steroids. We describe three patients with plasma cell cheilitis whose clinical condition responded rapidly to the intralesional injection of corticosteroids.

Adrenal Cortex Hormones↗

Acute generalized exanthematous pustulosis in a six-year-old boy.

Acute generalized exanthematous pustulosis (AGEP) presents with an abrupt onset of widespread pustules on erythematous base and rapid spontaneous healing. AGEP may have a variety of causative factors such as drugs, viral infection and exposure to mercury. We report a case of AGEP in a 6-year-old boy who presented with acute onset of fever and widespread pustular eruption on erythematous bases. Histologic examination showed neutrophilic subcorneal spongiform pustule. It is an uncommon condition in children.

Acute Disease↗

Mucinous eccrine nevus.

A 46-year-old man with an erythematous, tender, swollen patch on the dorsum of his left fourth toe visited us. The biopsied tissue showed a proliferation of normally structured eccrine glands and ducts surrounded with abundant materials confirmed as mucin by toluidine blue stain. Mucinous eccrine nevus is an extremely rare entity, and only two cases have been reported in the literature. We describe a case of mucinous eccrine nevus which was late in onset and presented as a swollen patch.

Diagnosis, Differential↗

Age-dependent change of uric acid level in the dermis using cutaneous microdialysis.

BACKGROUND: We had proposed the usefulness of cutaneous microdialysis for the study of antioxidants in the skin. OBJECTIVE: We designed a study analyzing the level of uric acid in the skin, one of the major antioxidants, for an age-dependent change. METHODS: 16 healthy male volunteers were divided into two groups according to age. Eleven subjects were in their 3rd decade, under 30 years of age (young group) and the others were their 8th decade (old group), over 70 years of age. Dialysate samples were analyzed using high-performance liquid chromatography analysis. RESULTS: In the young group the mean level of uric acid was 31.9+/-16.1 microg/ml, while in old group it was 13.4+/-5.2 microg/ml. CONCLUSION: This result demonstrated an in vivo state of antioxidant level in the human skin and the age-dependent difference was concordant with other in vitro or ex vivo studies; therefore, cutaneous microdialysis could be used in analysis and monitoring studies including human antioxidants and anti-aging.

Adult↗