High H2 adsorption by coordination-framework materials.
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Journal Article↗
Biomedical subjects
Junhua Jia
Publications and source records attributed to Junhua Jia.
Triggered ligand release coupled to framework rearrangement: generating crystalline porous coordination materials.
A robust 3-D porous structure of formula [Ln2(PDC)3(DMF)2](infinity) has been constructed from lanthanide cations (Ln = Er3+ or Y3+) and the non-linear anionic bridging ligand, pyridine-3,5-dicarboxylate (PDC2-) in dimethylformamide (DMF). The solvated framework polymers {[M2(PDC)3(DMF)2].n(solv)}(infinity) (M = Er, Y) undergo a solid-state, crystal-to-crystal reaction upon heating and are converted via loss of both sorbed and coordinated solvent and rearrangement of the framework core to give a desolvated and porous form with retention of structural integrity. This structural transfer is the first crystallographically characterized system with lanthanide metal ions. These porous products are shown to be effective absorbants for H2, N2, and benzene.
Journal Article↗
Taurine chloramine inhibits lymphocyte proliferation and decreases cytokine production in activated human leukocytes.
Previously, we described the inhibition of proinflammatory mediators such as nitric oxide, tumor necrosis factor-alpha (TNF-alpha), and prostaglandin E2 by taurine chloramine (Tau-Cl) in activated rodent macrophages. We also demonstrated that Tau-Cl suppressed superoxide anion, IL-6, and IL-8 production in activated human polymorphonuclear leukocytes separated from peripheral blood. In these studies, we report the effect of Tau-Cl on lymphocyte proliferation and the production of cytokines by activated human peripheral blood mononuclear leukocytes. Adherent and nonadherent leukocytes were activated using lipopolysaccharide (LPS) and phytohemagglutinin (PHA), respectively, in the presence or absence of Tau-Cl. Tau-Cl significantly suppressed lymphocyte proliferation as measured by tritiated (3H) thymidine. Production of IL-6, IL-8, and IL-2 in PHA-activated nonadherent leukocytes was inhibited by Tau-Cl. The production of IL-1beta, IL-6, and IL-8 was also decreased in LPS-activated adherent monocytes by Tau-Cl. These data demonstrate that the ability of Tau-Cl to modulate the immune response is not species specific and extends to human leukocytes.
Humans↗