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Junji Tanaka

Publications and source records attributed to Junji Tanaka.

78 records · Page 5Linked to original sources

[Primary adrenal lymphoma: a case report and literature review in Japan].

A 78-year-old male was admitted to our hospital complaining of nausea, general fatigue and anorexia in November, 1999. Clinical findings on admission were weight loss and dehydration but surface lymph nodes were not palpable. Masses in the bilateral adrenal glands were detected by ultrasonography, computed tomography and magnetic resonance imaging. Laboratory examinations revealed hyponatremia and hyperkalemia. Subsequent endocrine function tests showed normal serum cortisol and increased adrenocorticotropic hormone (ACTH) levels. Rapid ACTH test and cortico-hormone releasing hormone (CRH) test revealed insufficient secretion of cortisol. The histological diagnosis of the adrenal gland by laparotomy was diffuse large B-cell lymphoma. We diagnosed primary adrenal lymphoma with adrenal insufficiency. The patient underwent hormone supplementary therapy and chemotherapy, but he died two months later. We report on this rare primary adrenal lymphoma case and summarize the reports of this disease in the Japanese literature.

Adrenal Gland Neoplasms↗

[The potential patient skin injuries from radiologically guided interventional procedure: the present condition and recommendable measure].

Radiologically guided interventional procedures may result in excessive radiation dose for the patients. During the last decade, more than 70 cases of radiation skin injuries have been reported. This may be partly because the potential dangers of X-radiation are not yet well recognized by the physicians, and also by lacking of practical and reliable way to monitor the dose of X-ray radiation at the radiology suite. The author presents a few recommendable techniques to monitor the patient's radiation doses during interventional radiological procedures, which may be helpful in preventing patient's radiation injury.

Humans↗

Successive cultures of mature hepatocytes for hepatocyte autotransplantation to assist liver function after liver resection for cancer.

We developed a method for the rapid successive cultures of adult rat mature hepatocytes on plastic dishes while avoiding viral transformation or co-culture with other cell lines. This method also allows for culturing adult human mature hepatocytes up to the secondary culture. These can be expected to provide a good source for hepatocyte autotransplantation, and, combined with the previously reported methods for the transplantation of hepatocytes into the spleen, a promising option for the support of liver function after liver resection for cancer without the need for immunosuppressive agents.

Adult↗

Usefulness of early-phase helical CT for detecting recurrent rectal cancer.

PURPOSE: To evaluate the usefulness of dynamic enhancement of helical CT in the detection of local recurrence of resected rectal cancer. MATERIALS AND METHODS: In 142 patients with a history of curatively resected T2 or T3 rectal cancer, follow-up plain CT indicated that they had a loco-regional recurrent tumor; consequently, they underwent follow-up pelvic helical CT providing accurate early-phase contrast enhancement in the lower pelvic region. The patients were divided into four groups according to the grade of contrast enhancement of the suspected mass-like lesion before and after contrast enhancement, and the correlation between groups and results obtained by biopsy and/or surgery were assessed. If no correlation was found, patients were followed up for a period lasting from 400 days to two years. As of June 2002, results had been obtained for 80 patients, and correlation between these results and grouping by contrast enhancement ratio was analyzed. RESULTS: All patients in the highest-grade group (n=10) had local recurrence. When only the highest-grade group was considered positive, there were no false positives and only one false negative. CONCLUSION: Our results suggest that early-phase contrast enhancement is useful for accurately detecting recurrent rectal cancer. This can be easily achieved using the SmartPrep function, and should be used to distinguish recurrent tumors from postsurgical scar tissue, because these two tissue types do not exhibit similar enhancement patterns.

Adenocarcinoma↗