PubMed Health⌕ Search

Biomedical subjects

Jurij R Bilyk

Publications and source records attributed to Jurij R Bilyk.

13 recordsLinked to original sources
PubMed2006

Orbital decompression as an alternative management strategy for patients with benign tumors located at the orbital apex.

PURPOSE: Tumors located in the intraconal portion of the orbital apex, especially those inferior to the optic nerve, can be difficult to access surgically, carrying a significant risk of ocular morbidity. The purpose of this study was to investigate outcomes in 5 patients with benign-appearing but symptomatic tumors located in the intraconal portion of the orbital apex in which orbital decompression was performed as an alternative management strategy to resection. DESIGN: Retrospective interventional case series. PARTICIPANTS: Five patients were diagnosed with a compressive optic neuropathy secondary to a benign-appearing tumor at the orbital apex. INTERVENTION: Each patient underwent surgical decompression of the affected orbit. None of the patients had the tumor biopsied or resected. MAIN OUTCOME MEASURES: Best-corrected visual acuity (VA), pupillary responses, visual fields (VFs), color vision, and orbital imaging. RESULTS: Each of the patients demonstrated improvement in visual function, as measured by VA, VFs, and, in some cases, color vision. One patient required a second orbital decompression for recurrent optic neuropathy 4 years after the initial decompression. Complications included ptosis and enophthalmos in 2 patients and diplopia in the extreme right gaze in 1 patient. CONCLUSIONS: Orbital decompression is a therapeutic option for patients with compressive optic neuropathies from benign orbital apex tumors, offering potential improvement in optic nerve function while sparing morbidity from attempts at surgical resection.

Adult↗
PubMed2006

Simultaneous endoscopic antrostomy and orbital reconstruction in silent sinus syndrome.

PURPOSE: To review the surgical outcome of five cases of silent sinus syndrome (SSS) who were treated with simultaneous endoscopic antrostomy and orbital implant placement. Patients with SSS often present with cosmetic change to their facial appearance (enophthalmos, hypoglobus, deep upper lid sulcus). DESIGN: Retrospective case series. METHODS: Chart review was performed for cases of SSS who were seen between 1995 and 2003 in two tertiary eye care centers. The age, affected side, presenting symptoms and duration, history of trauma, smoking, and chronic sinusitis, degree of enophthalmos and hypoglobus were recorded. RESULTS: All patients had a satisfactory post-operative result with correction of the enophthalmos, hypoglobus, and deep upper lid crease deformity. There were no untoward effects such orbital implant infection, diplopia, vision loss or hematoma. CONCLUSION: Simultaneous endoscopic antrostomy and orbital implant placement can achieve a satisfactory outcome in cases of SSS with significant enophthalmos and hypoglobus. Orbital implant placement carries minimal risks and should not be delayed only to potentially avoid infection, diplopia, or visual loss, as these events are unlikely.

Adult↗
PubMed2005

Bone from an orbital floor fracture causing an intraocular foreign body.

PURPOSE: To describe the ophthalmoscopic and radiologic findings of a patient who sustained blunt orbital trauma. A piece of bone from the fractured orbital wall caused an intraocular foreign body. DESIGN: Case report. METHODS: An 18-year-old man underwent full ophthalmoscopic examination 1 week after sustaining blunt ocular trauma to the right eye while playing basketball. B-scan ultrasonography and computed tomography of the orbits were also performed. RESULTS: Visual acuity, intraocular pressure, and anterior segment examination were normal. Funduscopic examination revealed a fragment of bone that had penetrated the sclera, choroid, and retina. A hole in the sclera was visible. No treatment was performed. Three months later, the patient had no ocular complaints or complications as a result of this injury. CONCLUSION: Bone from a patient's orbit may cause an intraocular foreign body that may be followed conservatively in certain circumstances.

Adolescent↗
PubMed2005

Isolated optic nerve lymphoma diagnosed by optic nerve biopsy.

PURPOSE: To report a case of isolated optic nerve lymphoma diagnosed by optic nerve biopsy. DESIGN: Case report. METHODS: A 66-year-old woman was referred to the Neuro-Ophthalmology Service because of a decrease in visual acuity and right optic disk edema. RESULTS: A magnetic resonance image of the brain showed only enhancement of the optic nerve. An examination that included ANA, c-ANCA, p-ANCA, Lyme titers, FTA-ABS, ACE level, chest x-ray, and lumbar puncture was negative. Because of rapid progression on clinical examination and serial imaging, an optic nerve biopsy was performed, which showed B-cell lymphoma. CONCLUSION: Optic nerve lymphoma can be confused with a variety of inflammatory and neoplastic infiltrations of the optic nerve on clinical and radiographic examinations. Optic nerve biopsy can be valuable in diagnosing isolated optic nerve lymphoma if other diagnostic tests are unrevealing, but the procedure carries considerable risk of loss of visual acuity and should be recommended judiciously.

Aged↗
PubMed2005

Incidence of infraorbital hypesthesia and sinusitis after orbital decompression for thyroid-related orbitopathy: a comparison of surgical techniques.

PURPOSE: To compare the incidence of postoperative infraorbital (V2) hypesthesia and sinusitis between transantral/Caldwell-Luc and transconjunctival orbital decompression for thyroid-related orbitopathy. METHODS: A retrospective review of all orbital decompressions from January 1994 to January 2001 performed by one surgeon was done. Seventy-eight patients (133 orbits) with thyroid-related orbitopathy underwent orbital decompression for compressive optic neuropathy, exposure keratopathy, or uncontrolled intraocular pressure. Main outcome measures were the presence of V2 hypesthesia and sinusitis determined at 3 postoperative evaluations (1 to 2 weeks, 1 to 3 months, 3 to 6 months). RESULTS: The incidence of V2 hypesthesia in the transconjunctival group declined from 29.2% (19/65) to 6.1% (4/65), whereas the incidence of V2 hypesthesia in the transantral/Caldwell-Luc group decreased from 68.2% (43/63) to 46% (29/63) over the postoperative course. The rate of sinusitis in the transconjunctival group stayed constant at 6.1% (4/65) at early and late postoperative visits, whereas the transantral group rate of sinusitis declined from 33.3% (21/63) to 9.5% (6/63). CONCLUSIONS: Transconjunctival orbital decompression results in a statistically significant decrease of early and late postoperative infraorbital hypesthesia and early postoperative sinusitis when compared with the transantral approach.

Decompression, Surgical↗
PubMed2005

Orbital lymphoma with concomitant sarcoid-like granulomas.

A 41-year-old man presented with chronic eyelid swelling, conjunctival injection, and decreased ocular motility in all gaze directions. MRI showed bilateral enlarged extraocular muscles, including the tendons. Laboratory tests revealed elevated levels of angiotensin-converting enzyme. An orbital biopsy showed collections of monotonous small lymphocytes, and granulomatous inflammation that included multinucleated giant cells, predominantly Langhans type. Flow cytometric analysis of tissue demonstrated a light chain-restricted clonal population of B cells, a finding that confirmed the morphologic impression of lymphoma. This case demonstrates that elevated angiotensin-converting enzyme and granulomatous inflammation can occur in lymphoma. Careful histopathologic examination and flow cytometric analysis are essential to avoid an erroneous diagnosis that could lead to inappropriate management.

Adult↗
PubMedDate not supplied

The ticking time bomb.

A man with orbital myositis and optic neuritis tested positive serologically for multiple tick-borne diseases. Erlichiosis, babesiosis, and Lyme disease may occur together and affect the eye or orbit.

Animals↗
PubMedDate not supplied

Preliminary study of positron emission tomography in the detection and management of orbital malignancy.

PURPOSE: To determine the clinical efficacy of positron emission tomography (PET) in the treatment of patients with orbital malignancy. METHODS: Prospective, consecutive case series to assess the ability of PET to (1) identify lesions previously demonstrated on CT or MRI; (2) characterize the metabolic activity of these lesions; and (3) determine the presence of metabolically active metastases elsewhere in the body. RESULTS: Eighteen patients with suspected orbital malignancies, ages 32 to 78 years, underwent PET in addition to CT and/or MRI. Sixteen of 18 also underwent orbital biopsy. Histopathologic diagnosis included lymphoma (55%), carcinoma (22%), melanoma (11%), sarcoma (5.5%), and lymphoid hyperplasia (5.5%). All orbital lesions were seen on conventional imaging. Overall, 61% of orbital lesions were demonstrated on PET, including 55% of tumors that were lymphoproliferative and 100% (n = 5) of other malignancies. PET was useful in ruling out tumor recurrence after exenteration in 2 patients. CONCLUSIONS: In this small clinical series, PET proved effective in demonstrating nonlymphoproliferative orbital malignancy. This series is too small to study any correlation between histopathologic aggressiveness and PET findings in orbital lymphoma.

Adult↗