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Biomedical subjects

K A Freissler

Publications and source records attributed to K A Freissler.

4 recordsLinked to original sources

[Scanning electron microscopic study of 12 lenses of two types of soft acrylic intraocular lenses].

BACKGROUND: Evaluation of the surface properties of two models of one-piece foldable acrylic intraocular lenses (IOLs) before and after folding and passing the IOLs through an injector. METHODS: We studied two foldable IOL models made of a polymethacrylate/2-hydroxyethylmethacrylate copolymer: EasAcryl 1(R) (Chiron) and Raysoft(R) 547H (Rayner). Twelve IOLs of each design with different diopters were examined. Light and scanning electron microscopy were performed before and after IOL folding and passing the IOLs through a Micra G103 injector (Chiron Adatomed) and an IC-2BU inserter cartridge (Chiron Microsert II). RESULTS: All IOLs presented a homogeneous surface and smoothly finished edges of haptics and optics. The inner edges of all IOL haptics and the optic edges of some IOLs had ridges at high magnifications. No IOL demonstrated any folding defects of the optic such as a folding line or scratches. Three of 16 folded IOLs showed defects or cracking of the IOL haptics due to incomplete placement in the inserter cartridge. CONCLUSIONS: The two models of soft acrylic intraocular lenses showed excellent surface quality. After folding and injection process no alteration of the optics was detected in any of the IOLs. However, the IOLs need careful placement in the inserter cartridge to avoid haptic damage.

Acrylates↗

[Central serous chorioretinopathy. Clinical, fluorescein angiography and demographic aspects].

UNLABELLED: The purpose of this retrospective study was to analyze the demographic characteristics of central serous chorioretinopathy (CSC). METHODS: Findings of 100 consecutive subjects with CSC were evaluated. Clinical and fluorescein angiographic findings, demographic characteristics, and visual acuity were analyzed. RESULTS: The age of the patients ranged from 28 to 68 years with a mean of 43 years. No significant sex differences were found concerning age and other parameters. The highest age peak was in the group of women. The male to female ratio was 5:1. Patients with chronic CSC were significantly older (P = 0.015) than patients with the other angiographic findings. Median visual acuity was 0.5. In 40% bilateral characteristics of CSC were found. Clinical and fluorescein angiographic findings showed no significant correlation with visual acuity. CONCLUSION: The range of age distribution in CSC is wide. In older patients distinguishing CSC from age-related macular degeneration can be difficult.

Adult↗

Allergic diseases of the lids, conjunctiva, and cornea.

Allergic ocular diseases are frequently encountered in the ophthalmologic practice. The term covers a wide array of severity, ranging from seasonal allergic conjunctivitis to the sight-threatening variant of atopic keratoconjunctivitis. The pathophysiology of these diseases is complex. Recent studies showed that nerve growth factor and interleukin IV, seem to play a role in these mechanisms.

Allergens↗

The cornea and systemic diseases.

Multiple systemic diseases imply corneal involvement. Corneal pathology may also be a presenting sign or may herald a forthcoming relapse of chronic disease. The presence of ulcerative keratitis in patients with rheumatoid arthritis can be associated with systemic lethal vasculitis. Epithelial fragility of the cornea is correlated to the presence of diabetic retinopathy. Rarely, interstitial keratitis may be the presenting sign of sarcoidosis. Corneal involvement in oculomucocutaneous syndromes continue to present a therapeutic challenge. Infectious and possibly drug-induced corneal pathology is a recurrent problem in patients with AIDS.

Corneal Diseases↗