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Biomedical subjects

K A Lebedev

Publications and source records attributed to K A Lebedev.

At least 19 recordsLinked to original sources
PubMed1998

[The comparative clinico-immunological characteristics of the course of mandibular fractures in patients in Yakutsk and Moscow].

Ninety-seven patients with mandibular fractures were examined: 55 in Yakutsk and 42 in Moscow. In the Yakutsk patients the inflammatory process much more frequently progressed to the development of infectious inflammatory complications at the site of fracture than in Moscow. More expressed shifts in the immunogram were observed mainly in the patients who later developed infectious inflammatory complications.

Adolescent↗
PubMed1997

[The combined treatment of lichen ruber planus of the mouth mucosa].

The treatment of 53 patients with lichen planus of the buccal mucosa included common methods of detoxication and immunomodulators in order to normalize the immune status and was supplemented with applications of codfish oil enriched with polyunsaturated fatty acids. As a result of such treatment, the duration of exacerbation was shorter and a stable more than one-year remission was attained, associated with normalization of the immunological parameters. In patients with the erosive ulcerative form of lichen local applications of codfish oil and gargling with Potentilla tormentilla tincture were conducive to a sooner control of the process.

Adjuvants, Immunologic↗
PubMed1997

[A comparative analysis of the course of odontogenic phlegmons of the face and neck area in patients from Yakutsk and Moscow].

A total of 126 patients with odontogenic inflammatory diseases were examined, 54 of these in Moscow and 72 in Yakutsk. The clinical and immunological parameters were assessed on days 2 and 6 after similar operations. In residents of Yakutsk the inflammatory process was associated with a more expressed intoxication and coursed 1.5 to 2 days longer than in Muscovites; moreover, the residents of Yakutsk developed higher leukocytosis and a drop of T-lymphocyte level with the predominance of T-helpers. Hence, odontogenic inflammations take mainly a hyperergic course in Yakutsk and a normergic one in Moscow.

Adolescent↗
PubMed1995

[Ways to prevent and treat disseminated inflammatory diseases of the maxillofacial area and their complications].

The authors analyze the results of diagnosis and treatment in 1062 patients with diffuse inflammatory diseases of the maxillofacial area and of complications of these diseases, such as mediastinitis, thrombosis of the cavernous sinus of the dura mater, meningoencephalitis. Improvement of the program of diagnosis and treatment helped improve the results: mortality from sepsis reduced from 50 to 26%. Approaches to prevention of progressive purulent infection are outlined.

Acute Disease↗
PubMed1991

[Use of an immunogram in the clinical management of patients with phlegmon of the maxillofacial area].

Indices of immunogram (levels of T-, B-lymphocytes, amount of O-cells, indices of T-helpers and T-suppressors, adhesive and phagocytic activity of neutrophils, leukogram) were repeatedly studied in patients with phlegmon of maxillofacial area. A short-term recovery of the levels of T- and B-lymphocytes makes it possible to control the completeness of the surgical procedure. Shifts in the immunogram allow to reliably and objectively follow the development of the inflammatory process in patients with phlegmons of maxillofacial area.

Cellulitis↗
PubMed1989

[Practical objectives of mass immunologic screening of the population].

Techniques for conducting a combination of immunological methods have been elaborated for wide introduction into public health practice. The five main tasks have been substantiated in detail: two are connected with treatment and three with prophylaxis of diseases. These are: (I) prognosis of the course and control of the effectiveness of disease treatment; (2) compiling an immunological passport of people for the improvement of the effective use of the immunogram in clinical practice; (3) detection of genetic and acquired defects of the immune system components; (4) detection of delayed formation and restructuring of the immune system in the process of the organism's age-hormonal reorganization; (5) control of the development of immunological failure (its appearance, course and removal).

Humans↗
PubMed1987

[Features of the immune status of patients with infectious-allergic bronchial asthma before the onset of an exacerbation].

A study was made of the immune status in patients with infectious-allergic bronchial asthma in the phase of clinical manifestations before the onset of exacerbation 2 mos after examination, and in patients with a favorable course of disease without exacerbations during the same period of time. The assessment of the immune status was based on a study of the balance of interrelationships in a set of immunological parameters including the chief indices of cellular and humoral immunity (T- and B-lymphocytes, phagocytosing and rosette-forming neutrophils, indices of cell activity in exercise tests, the levels of serum and secretory immunoglobulins--a total of 33 indices). Sharp changes in values and direction of interrelationships in numerous combinations of parameters, especially in those which included the content of immunoglobulins in the sputum, indices of the activity of neutrophils and exercise tests were noted in the patients with exacerbation for 2 mos after examination as compared to those who developed no exacerbations. A special table for prediction of a course of infectious-allergic bronchial asthma was based on a study of the balance of interrelationships. Data obtained from the table corresponded to considerable changes revealed in the balance of interrelationships among components of the immune system 1-2 mos before the appearance of the clinical signs of exacerbation of the disease.

Adult↗