Biomedical subjects
Publications and source records attributed to K A Lieberman.
A 49-year-old man developed a gliosarcoma with prominent osteoid components 15 months after surgical resection and postoperative radiation and chemotherapy for a right frontal glioblastoma multiforme. The recurrent tumor was distinguished from the original lesion by the presence of dense ossification, visible on CT, at the original tumor site. The relevant literature is reviewed.
RATIONALE AND OBJECTIVES: The authors evaluated the clinical utility and potential applications of a binocular three-dimensional (3D) image display in diagnostic radiology. MATERIALS AND METHODS: Rotating video displays of computed tomographic (CT), magnetic resonance (MR) angiographic, and digital subtraction angiographic (DSA) image data were used to generate stereoscopic image displays with a 3D appearance. Eight physicians viewed and scored eight skeletal and eight vascular-interventional studies with a planar display mode and a cathode ray tube. Each physician then viewed the 3D display of the same data and assessed the change in image findings, as well as any corresponding changes in level of diagnostic confidence. RESULTS: Image findings changed in 78 (61%) of the 128 studies after viewing the 3D displays. In 94 (73%) of all 128 studies, the interpreters reported increased confidence in their perception of the findings. Results for the vascular-interventional and skeletal cases were generally very similar. CONCLUSION: Binocular 3D stereoscopic displays from rotating images were reported to provide better image conceptualization and a higher degree of confidence in the findings on the images.
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We report five cases of tumors occurring in three children and in two adults. The tumors had unusual histomorphology and a mixture of ependymal and piloid-like astrocytic features and a myxoid stroma similar to myxopapillary ependymomas. MR imaging in three of the cases showed aggressive, intensely enhancing partially cystic hypothalamic-suprasellar masses near midline and near the floor of the third ventricle. In the three pediatric cases, the tumor encased the circle of Willis. This newly characterized tumor, the tanycytoma, has neoplastic cells with histomorphologic and ultrastructural characteristics similar to those of the tanycyte.