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Biomedical subjects

K A Rogov

Publications and source records attributed to K A Rogov.

18 recordsLinked to original sources

[The condition of the middle ear mucosa in chemodectoma of the tympanic glomus at the early stage of the disease].

28 samples of tissue from the middle ear obtained at removal of chemodectoma were studied histologically. Investigation of the tympanic cavity mucosa has shown correlation between the severity of fibroatrophic changes in the middle ear mucosa and duration of the disease. Pathomorphological alterations in the middle ear mucosa at early stages of chemodectoma (stage I and II) are similar to those in chronic lingering mucositis.

Adult↗

[Primary heart neoplasms].

The work analyses the anatomomorphological characteristics of primary tumors of the heart in 106 patients; in 101 patients the tumor was benign (myxoma, neurinoma, rhabdomyoma) and in 5 malignant (angiosarcoma, liposarcoma). Surgical treatment was conducted in 99 patients; hospital lethality was 7.1%. Six patients who refused an operation died at other therapeutic institutions, one patient died on admission to the clinic from occlusion of the left atrioventricular orifice by the tumor. It is pointed out that the diversity and the various degree of the clinical manifestations of the disease are predetermined by the localization and morphological characteristics of the new growths, their size, and mobility. The authors emphasize that knowledge of the anatomomorphological features of primary tumors of the heart and their early diagnosis are conducive to a differential approach in each concrete situation and to the choice of the optimal volume of an urgent surgical intervention.

Adolescent↗

Extracorporeal mechanical pulsatile pump and its significance for myocardial function recovery and circulatory support.

The authors performed 12 acute (on dogs) and 12 chronic (on calves) assisted circulation experiments with the use of the total extracorporeal mechanical pump (TEMP) artificial ventricles. The functional morphological research of the myocardium suggests that in addition to the possibility of the biological heart function full replacement, the artificial ventricle also helps recover damages in both the myocardial infarction and distal zones. The critical time period up to the onset of artificial circulation is not more than 2 h, and after that myocardial changes are irreversible.

Animals↗

[Nonspecific resistance and inflammation in patients with odontogenic phlegmons of the maxillofacial area].

Presented are data on morphological characteristics of maxillofacial odontogenic phlegmons observed in 98 patients with chronic periodontitis. The phlegmons have arisen in the presence of chronic inflammation of the soft tissue. Microbial flora in the inflammation focus proved opportunistic, abundant in nonclostridial anaerobic agents. Its composition contributed to morphological varieties of the phlegmons. There is a relationship between apparent destructive fasciitides and myositides and aerobic-anaerobic associations. Mechanisms of resistance to infection involve inhibited bactericidal activity of nonenzymatic cationic proteins of polymorphonuclear leukocytes reflecting nonspecific resistance in inflammation. Immunity status of the organism seems normal.

Adolescent↗

Experimental and clinical ventricular bypass during acute heart failure.

Mechanical support of the failing heart in the form of bypass of the left and right ventricles by roller pumps was used in 25 dogs with model cardiogenic shock. Early application of left ventricular bypass in acute heart failure normalizes the myocardial bioenergy state and promotes reversible changes in myocardial ultrastructure as demonstrated by an increased surface area of mitochondrial cristae. On the basis of hemodynamics and morphology, we conclude that pump-aided bypass of ventricles without synchronization is a simple and effective method of circulation assistance. Mechanical support duration from 1 to 138 hours has been used in 10 patients following corrective heart surgery.

Acute Disease↗

[Heart myxoma histogenesis in the light of its histological and ultrastructural features].

In 168 cases of heart myxoma histological and electron-microscopic examination have revealed signs of embryonal endothelium capable of vasoformation and glycoprotein and glycosaminoglycanes synthesis in myxoma cells. Neither differentiation of myxomas cells up to mature endotheliocytes no signs of malignant transformation was found. According to the authors, heart myxoma is a true benign dysontogenetic tumor originating from embryonal endothelium. The term myxoma does not reflect morphological entity of the tumor and the authors suggest to call it embryonal endocardial endothelioma.

Adolescent↗

[Family myxoma of the heart with metachronic multiple growth].

A case of familial heart myxoma in 4 members of one family combined with myxomic (hamartomatous) syndrome is reported. The tumor in a proband was characterized with a multiple growth in various heart chambers. Five operations were made in the proband for 16 years and seven myxomas of different locations were removed. Myxomas originating from the endocardium of the interatrial septum oval hole were removed in 3 members of his family. The case confirms the conception of heart myxoma origin from endothelial hamartia of the endocardium.

Adolescent↗