PubMed Health⌕ Search

Biomedical subjects

K Abumi

Publications and source records attributed to K Abumi.

At least 37 records · Page 2Linked to original sources

Dynamic motion analysis of normal and unstable cervical spines using cineradiography. An in vivo study.

STUDY DESIGN: Cervical motion patterns were analyzed in a normal population and in patients with cervical instability by using cineradiography. OBJECTIVES: To determine normal and pathologic motion patterns in the cervical spine through an in vivo continuous motion analysis. SUMMARY OF BACKGROUND DATA: Cineradiographic techniques have been used in a limited number of studies to quantify spinal motion. There is a paucity of information regarding dynamic motion patterns in normal and pathologic cervical spines. METHODS: Ten healthy subjects and 12 patients with unstable cervical spines (C1-C2 subluxation caused by rheumatoid arthritis, n = 10; instability below C2, n = 2) were studied. Cervical motion during flexion from the maximum extension position was recorded using cineradiography. Cervical segmental motions (C1-C2 to C5-C6) were continuously measured through quantifying cineradiographic images projected on a digitizer. RESULTS: Normal cervical spines showed a well-regulated stepwise motion pattern that initiated at C1-C2 and transmitted to the lower segments with time lags. Pathologic spines showed a different order of onset of segmental motion. In patients with rheumatoid arthritis who had atlantoaxial subluxation, C1-C2 motion initiated significantly earlier than C2-C3 motion. In patients with segmental instability below C2, motion in the unstable segments preceded that in the upper intact segments. CONCLUSIONS: Different motion patterns were observed between normal and pathologic cervical spines. Cineradiographic motion analysis is a valuable adjunctive technique, especially in diagnosis or evaluation of conditions that cannot be identified through conventional radiographic examination.

Adult↗

One-stage posterior decompression and reconstruction of the cervical spine by using pedicle screw fixation systems.

OBJECT: This retrospective study was conducted to analyze the results of one-stage posterior decompression and reconstruction of the cervical spine by using pedicle screw fixation systems in 46 patients. METHODS: Causes of cervical myelopathy in these 46 patients included spondylosis or ossification of the posterior longitudinal ligament, rheumatoid arthritis, metastatic or primary vertebral tumors, cervical spinal injuries, and spinal cord tumor. Thirty-three patients underwent this one-stage procedure as primary surgery. In the remaining 13 patients who had previously undergone laminectomies, the one-stage procedure was performed as salvage surgery. Cervical pedicle screws were inserted into the pedicles after probing and tapping. Graft bone was placed on the bilateral lateral masses, and pedicle screws were interconnected longitudinally by either plates or rods. Postoperatively, 26 patients showed improved neurological status (at least one grade improvement on Frankel's functional classification). There were no cases of neurological deterioration postoperatively. Solid bony fusion was obtained in all patients, except in seven patients with metastatic tumor who did not receive bone grafts. Correction of kyphosis was satisfactory. Postoperative radiological evaluation revealed that 10 (5.3%) of 190 screws inserted into the cervical vertebrae had perforated the cortex of the pedicles; however, no neurovascular complications were caused by the perforations. CONCLUSIONS: The pedicle screw fixation procedure, which does not require the lamina to be used as a stabilizing anchor, has proven to be valuable when performing one-stage posterior decompressive and reconstructive surgery in the cervical spine. The risk to neurovascular structures in this procedure, however, cannot be completely eliminated. Thorough knowledge of local anatomy and application of established surgical techniques are essential for this procedure.

Adult↗

Pathologic features of spinal disorders in patients treated with long-term hemodialysis.

STUDY DESIGN: Pathologic features of hemodialysis-associated spinal disorders were evaluated using preoperative radiographic images and histologic findings of the spinal lesions resected during surgery. OBJECTIVES: To investigate the pathology of hemodialysis-related spinal disorders and to determine the role of amyloidosis in the establishment of severe destruction of the spine. SUMMARY OF BACKGROUND DATA: The pathologic events leading to hemodialysis-associated spinal disorders are poorly understood. The distribution of amyloid deposits in the spine also has not been clarified. METHODS: Twenty patients with hemodialysis-associated spinal disorders were investigated regarding pathologic features of neural compression and spinal destruction. Preoperative radiographic images such as plain radiography, tomography, computed tomography, magnetic resonance imaging, and scintigraphy were assessed for the existence of an intracanal mass, hypertrophy of the ligamentum flavum, and destructive changes of the spinal components. Histologic examination also was conducted by light microscopy and scanning electron microscopy to determine the distribution pattern of amyloid deposits in the spinal components. RESULTS: Six patients with no destructive changes in the spine showed spinal canal stenosis. In the cervical spine, a main factor associated with spinal canal stenosis was the presence of intracanal amyloid deposits in three patients. In the lumbar spine, a main factor associated with spinal canal stenosis was hypertrophied ligamentum flavum in three patients. Destructive changes of the facet joints, intervertebral disc, and vertebral body were seen in the other 14 patients. Amyloid deposits were densely distributed at the enthesis of capsular fibers to the bone and in anular tears in the intervertebral discs. Vertebral end plates were destroyed by penetration of amyloid granulation into the vertebral body. Osteoclast activity in the destroyed vertebral bodies was enhanced, with no evidence of new bone formation. CONCLUSIONS: Amyloid deposits played an important role in the progression of spinal destruction and severe instability.

Adult↗

Stability of posterior spinal instrumentation and its effects on adjacent motion segments in the lumbosacral spine.

STUDY DESIGN: An in vitro biomechanical analysis of three anterior instability patterns was performed using calf lumbosacral spines. Stiffness of the constructs was compared, and segmental motion analyses were performed. OBJECTIVES: To clarify the factors that alter the stability of the spinal instrumentation and to evaluate the influence of instrumentation on the residual intact motion segments. SUMMARY OF BACKGROUND DATA: Recently, many adverse effects have been reported in fusion augmented with rigid instrumentation. Only few reports are available regarding biomechanical effects of stability provided by spinal instrumentation and its effects on residual adjacent motion segments in the lumbar-lumbosacral spine. METHODS: Eighteen calf lumbosacral spine specimens were divided into three groups according to instability patterns--one-level, two-level, and three-level disc dissections. Six constructs were cyclically tested in rotation, flexion-extension, and lateral bending of intact spines, of destabilized spine, and of spines with four segmental posterior instrumentation systems used to extend the levels of instability (Cotrel-Dubousset compression hook and three transpedicular screw fixation systems). During each test, stiffness values and segmental displacements were measured. RESULTS: The rigidity of the instrumented construct increased as the fixation range became more extensive. Although application of the instrumentation effectively reduced the segmental motion of the destabilized vertebral level, the motion at the destabilized level tended to increase as the number of unstable vertebral levels increased, and the fixation range of the instrumentation became more extensive. Instrumented constructs produced higher segmental displacement values at the upper residual intact motion segment when compared with those of the intact spine. In contrast, the instrumented constructs decreased their segmental displacement values at the lower residual intact motion segment with higher magnitude of the translational (shear) motion taking place compared with the intact spine in flexion-extension and lateral bending. These changes in the motion pattern became more distinct as the fixation range became more extensive. CONCLUSIONS: As segmental spinal instrumentation progresses from one level to three levels, the overall torsional and flexural rigidity of the system increases. However, segmental displacement at the site of simulated instability becomes more obvious. Application of segmental instrumentation changes the motion pattern of the residual intact motion segments, and the changes in the motion pattern become more distinct as the fixation range becomes more extensive and as the rigidity of the construct increases.

Animals↗

The role of anteromedial foraminotomy and the uncovertebral joints in the stability of the cervical spine. A biomechanical study.

STUDY DESIGN: The biomechanical role of the cervical uncovertebral joint was investigated using human cadaveric spines. Sequential resection of cervical uncovertebral joints, including clinical anteromedial foraminotomy, was conducted, followed by biomechanical testing after each stage of resection. OBJECTIVES: To clarify the biomechanical role of uncovertebral joints and clinical anteromedial foraminotomy in the cervical spine and their effects on interbody bone graft stability. SUMMARY OF BACKGROUND DATA: Although the biomechanical role of the cervical uncovertebral joints has been considered to be that of a guiding mechanism in flexion and extension and a limiting mechanism in posterior translation and lateral bending, there have been no studies quantifying this role. According to results in quantitative anatomic studies, anatomic variations exist in uncovertebral joints, depending on the vertebral level, articular angulation, and relative height of the joints. METHODS: Fourteen human functional spinal units at C3-C4 and C6-C7 underwent sequential uncovertebral joint resection, with each stage of resection followed by biomechanical testing. The uncovertebral joint was divided anatomically into three parts on each side: the posterior foraminal part, the posterior half, and the anterior half. The loading modes included torsion, flexion, extension, and lateral bending. A simulated anterior bone graft construct was also tested after each uncovertebral joint resection procedure. RESULTS: Significant changes in stability were observed after sequential uncovertebral joint resection in all loading modes (P < 0.05). The biomechanical contribution of uncovertebral joints decreased in the following order: the posterior foraminal part, the posterior half, and the anterior half. Unilateral and bilateral foraminotomy most affected the stability of the functional spinal unit during extension, causing a 30% and 36% decrease in stiffness of the functional spinal unit, respectively. The effect was less in torsion and lateral bending. After sequential resection, there was a statistically significant difference between decreases in torsional stiffness at C3-C4 and C6-C7 (P < 0.05). The stiffness of the simulated bone graft construct decreased progressively during flexion and lateral bending after each foraminotomy (P < 0.05). Increased bone graft height of 79% returned stability to the preforaminotomy level. CONCLUSIONS: This is the first study to quantitate the biomechanical role of uncovertebral joints in cervical segmental stability and the effect at each intervertebral level. The effect differs because of anatomic variations in uncovertebral joints. The major biomechanical function of uncovertebral joints includes the regulation of extension and lateral bending motion, followed by torsion, which is mainly provided by the posterior uncovertebral joints. This study highlights the clinical assessment of additional segmental instability attributed to destruction of the uncovertebral joints during surgical procedures or by neoplastic lesions.

Biomechanical Phenomena↗

Occipitoatlantal instability associated with articular tropism.

The authors report the case of a patient with rotatory posterior subluxation of the occiput on the atlas associated with tropism of the O-C1 articulations. Lateral flexion-extension plain films demonstrated 5 mm of posterior translation of the occiput on the atlas. Tomographs revealed tropism of the O-C1 articulations, and CT scans on extension demonstrated posterior rotatory subluxation of the occiput on the atlas. The patient had no osseous abnormality caudally below the atlantoaxial joint, and underwent posterior occipitoatlantal fusion by wiring. At the 4-year follow-up, the grafted bone had been incorporated, and the patient was completely free from preoperative symptoms. In the present patient, occipitoatlantal instability is presumed to have derived from articular tropism.

Adult↗

Effects of chondroitinase ABC and chymopapain on spinal motion segment biomechanics. An in vivo biomechanical, radiologic, and histologic canine study.

STUDY DESIGN: The biomechanical effects of chondroitinase ABC and chymopapain related to spinal segmental instability were investigated using a canine model, as well by as radiologic and histologic analyses. OBJECTIVES: To evaluate the biomechanical, radiologic, and histologic affects on the lumber intervertebral disc of chondroitinase ABC compared with chymopapain. SUMMARY OF BACKGROUND DATA: No study on the biomechanical effects of chondroitinase ABC has been reported. METHODS: Forty-eight lumbar intervertebral discs in eight beagles were randomly assigned to three groups and received one of three materials: chondroitinase ABC, chymopapain, or buffered saline, using a lateral percutaneous procedure. One week after injection, the animals were killed and the lumbar spinal motion segments were removed. Spinal segmental instability after chemonucleolysis was evaluated in spinal motion segments without posterior elements. Radiologic and histologic changes were also investigated. RESULTS: Spinal segmental instability and disc space narrowing were more greater in the chymopapain group than in the chondroitinase ABC group. Destruction of nucleus and anulus proteoglycans, indicated by loss of safranin-O staining, was less intense in chondroitinase ABC-injected discs. CONCLUSIONS: Chondroitinase ABC results in less spinal segmental instability, disc space narrowing, and destruction of proteoglycans in intervertebral disc matrix than chymopapain.

Animals↗

Pedicle screw fixation for nontraumatic lesions of the cervical spine.

STUDY DESIGN: This retrospective study was conducted to analyze the clinical results in 45 patients with nontraumatic lesions of the cervical spine treated by pedicle screw fixation. OBJECTIVES: To evaluate the effectiveness of pedicle screw fixation in reconstructive surgery for nontraumatic cervical spinal disorders. SUMMARY OF BACKGROUND DATA: Pedicle screw fixation for hangman's fracture of the axis and traumatic lesions of the middle and lower cervical spine has been reported; however, there have been no reports on pedicle screw fixation for nontraumatic lesions of the cervical spine. METHODS: Forty-five patients with nontraumatic lesions of the cervical spine underwent reconstructive surgery including pedicle screw fixation and fusion. Five patients underwent occipitocervical fixation for the lesion of the upper cervical spine, and one patient underwent separate occipitocervical fixation and cervicothoracic fixation. Cervical or cervicothoracic fixation was performed in 39 patients. Twenty-six of these patients underwent simultaneous laminectomy or laminoplasty. Supplemental anterior surgery was conducted for 15 patients. RESULTS: Solid fusion was obtained in all patients except eight with metastatic vertebral tumors who did not receive bone graft. Correction of kyphosis was adequate. There were no neurovascular complications, except one case of transient radiculopathy caused by screw threads. CONCLUSIONS: Pedicle screw fixation is a useful procedure for posterior reconstruction of the cervical spine. This procedure does not require the lamina for stabilization, and should be especially valuable for simultaneous posterior decompression and fusion. The risk to neurovascular structures, however, cannot be completely eliminated.

Adult↗

Anterior correction of thoracic scoliosis with Kaneda anterior spinal system. A preliminary report.

STUDY DESIGN: Analysis of the clinical results of 20 patients with thoracic scoliosis treated by anterior procedure with Kaneda anterior spinal system. OBJECTIVES: To evaluate the efficacy of the anterior surgical correction procedure with a new anterior instrumentation in thoracic scoliosis. SUMMARY OF BACKGROUND DATA: Posterior correction and fusion with posterior instrumentation has been a main component of the surgical management of thoracic scoliosis. However, to the best of the authors' knowledge, no clinical results of anterior instrumentation surgery for thoracic scoliosis have been published in the English literature. METHODS: Anterior correction and fusion using Kaneda anterior spinal system was performed in 20 patients with thoracic scoliosis (3 patients with King Type II curve, 13 with Type III, and 4 with Type IV). The average follow-up was 3 years, with a range of 2 years, 3 months to 4 years, 1 month. There were 1B patients with idiopathic scoliosis (13 adolescents and 5 adults) and 2 patients with a single thoracic curve caused by other etiologies. All patients had correction of scoliosis by fusion within the major thoracic curve. Radiographic evaluations were performed to analyze frontal, sagittal, and rotational deformities of the spine. RESULTS: The average correction rate of scoliosis was 71%. Above the instrumented levels, the correction rate was 75%. Preoperative kyphosis of the instrumented levels of 7 degrees was corrected to 14 degrees of kyphosis. The trunk shift was improved from 17 mm before surgery to 9 mm at final follow-up evaluation. The average improvement of the tilt-angle in the lower and vertebra of fusion was 81%, and was 83% in the stable vertebra. Apical vertebral rotation showed correction rate of 15% in patients without performing resection of the rib head joints and rod rotation maneuver (n = 6). However, the correction rate was improved to 58% after introduction of the technique discussed (n = 14). The angle of tangential rib deformity (rib hump) showed a correction rate of 50%. There was 1.2 degrees of frontal plane and 1.0 degree of sagittal plane correction loss within the instrumented area at final follow-up evaluation. At final follow-up, nonunion at the uppermost segment of the fusion range developed in one patient, and decompensation in the lumbar spine was observed in one patient with Type II curve. CONCLUSIONS: Anterior correction with Kaneda anterior spinal system provides excellent correction of the frontal curvature and sagittal alignment by fusing within the range of the major curve, without a significant loss of correction and implant failure. Rigid rotational deformity of the thoracic scoliosis is effectively corrected by resection of the rib head joints and rod rotation maneuver. However, too much correction of the thoracic curve should be avoided, to prevent decompensation of the lumbar curve, especially in Type II curves.

Adolescent↗

Risk factors and probability of vertebral body collapse in metastases of the thoracic and lumbar spine.

STUDY DESIGN: The associations between vertebral body collapse and the size or location of the metastatic lesions were analyzed statistically to estimate the critical point of collapse. OBJECTIVES: To determine risk factors for collapse, to estimate the predicted probability of collapse under various states of metastatic vertebral involvement, and to establish the criteria of impending collapse. SUMMARY OF BACKGROUND DATA: Pathologic vertebral collapse brings about severe pain and paralysis in patients with cancer. Prevention of collapse plays a significant role in maintaining or improving their quality of life. Because no previous study has clarified the critical point of vertebral collapse, however, the optimum timing for prophylactic treatment has been unclear. METHODS: The size and location of metastatic tumor from Th1 to L5 were evaluated radiologically for 100 thoracic and lumbar vertebrae with osteolytic lesions. The correlations between collapse and the following risk factors (x1-x4) were determined by means of a multivariate logistic regression model: x1, tumor size (the percentage of tumor occupancy in the vertebral body [% TO]); x2, pedicle destruction, x3, posterior element destruction; and x4, costovertebral joint destruction. RESULTS: Significant risk factors were costovertebral joint destruction (odds ratio, 10.17; P = 0.021) and tumor size (odds ratio of every 10% increment in %TO, 2.44; P = 0.032) in the thoracic region (Th1-Th10), whereas, tumor size (odds ratio of every 10% increment in %TO, 4.35; P = 0.002) and pedicle destruction (odds ratio, 297.08; P = 0.009) were main factors in the thoracolumbar and lumbar spine (Th10-L5). The criteria of impending collapse were: 50-60% involvement of the vertebral body with no destruction of other structures, or 25-30% involvement with costovertebral joint destruction in the thoracic spine; and 35-40% involvement of vertebral body, or 20-25% involvement with posterior elements destruction in thoracolumbar and lumbar spine. CONCLUSIONS: With respect to the timing and occurrence of vertebral collapse, there is a distinct discrepancy between the thoracic and thoracolumbar or lumbar spine. When a prophylactic treatment is required, the optimum timing and method of treatment should be selected according to the level and extent of the metastatic vertebral involvement.

Adult↗

Free vascularised fibular strut graft for anterior spinal fusion.

A vascularised fibular strut graft was used for anterior spinal fusion in 16 patients with spinal kyphosis. The procedure was abandoned in three because of difficulty in establishing a vascular anastomosis and in one because the grafted fibula dislodged two days after operation. One patient died after five days. Of the 11 remaining patients, there were seven males and four females. Their ages at the time of operation averaged 30.9 years (12 to 71). The number of vertebrae fused averaged 6.7 (5 to 9) and the length of fibula grafted averaged 10.9 cm (6.5 to 18). Average follow-up was 54 months (27 to 84). Bone union occurred at both ends of the grafted fibula in all 11 patients, with an average time to union of 5.5 months (3 to 8). We did not see a fracture of the grafted fibula. Two patients had postoperative complications; the graft dislodged in one and laryngeal oedema occurred two days after operation in the other. A vascularised fibular strut graft provides a biomechanically stable and long-standing support in spinal fusion because the weak phase of creeping substitution does not take place in the graft.

Adolescent↗

Anterior decompression and stabilization with the Kaneda device for thoracolumbar burst fractures associated with neurological deficits.

One hundred and fifty consecutive patients who had a burst fracture of the thoracolumbar spine and associated neurological deficits were managed with a single-stage anterior spinal decompression, strut-grafting, and Kaneda spinal instrumentation. At a mean of eight years (range, five years to twelve years and eleven months) after the operation, radiographs showed successful fusion of the injured spinal segment in 140 patients (93 per cent). Ten patients had a pseudarthrosis, and all were managed successfully with posterior spinal instrumentation and a posterolateral arthrodesis. The percentage of the canal that was obstructed, as measured on computed tomography, improved from a preoperative mean of 47 per cent (range, 24 to 92 per cent) to a postoperative mean of 2 per cent (range, 0 to 8 per cent). Despite breakage of the Kaneda device in nine patients, removal of the implant was not necessary in any patient. None of the patients had iatrogenic neurological deficits. After the anterior decompression, the neurological function of 142 (95 per cent) of the 150 patients improved by at least one grade, as measured with a modification of the grading scale of Frankel et al. Fifty-six (72 per cent) of the seventy-eight patients who had preoperative paralysis or dysfunction of the bladder recovered completely. One hundred and twenty-five (96 per cent) of the 130 patients who were employed before the injury returned to work after the operation, and 112 (86 per cent) of them returned to their previous job without restrictions. We concluded that anterior decompression, strut-grafting, and fixation with the Kaneda device in patients who had a burst fracture of the thoracolumbar spine and associated neurological deficits yielded good radiographic and functional results.

Adolescent↗

Phase lag of the intersegmental motion in flexion-extension of the lumbar and lumbosacral spine. An in vivo study.

STUDY DESIGN: The lumbar and lumbosacral segmental motions were analyzed in vivo using cineradiographic method. OBJECTIVES: To reveal the in vivo motion behavior of the lumbar and lumbosacral segments and their contribution to the whole lumbar motion. SUMMARY OF BACKGROUND DATA: Relation between the lumbar motion and hip joint motion has been well investigated. The lumbar motion preceded the hip flexion in forward bending and delayed from extension of the hip joints in backward bending. However, it remains unclear how the lumbar and lumbosacral segmental motion contributed to the whole lumbar motion in vivo. METHODS: Eight healthy male subjects participated in this study. The lower lumbar and lumbosacral motion (L3-S1) was recorded using cineradiography during flexion and extension. Each trunk motion was carried out from the neutral position to the maximum position. Segmental rotation and translation were measured sequentially at the L3-L4, L4-L5, and L5-S1 motion segments. RESULTS: Intersegmental motion lags were observed between the lumbar and lumbosacral motion segments during flexion. The lower lumbar and lumbosacral motion (L3-S1) was initiated at the L3-L4 motion segment. The L4-L5 segmental motion delayed from the L3-L4 motion by an average of 6 degrees and preceded the L5-S1 motion by an average of 8 degrees. In extension, motions in the L3-L4 and L4-L5 segments were small, and the L5-S1 segmental motion only contributed to the total lower lumbar motion. CONCLUSIONS: The lumbar and lumbosacral segmental motions occurred not simultaneously but stepwise from the upper level with intersegmental motion lags during flexion. These intersegmental motion lags were much larger than the neutral zone in vitro, which implied the neutral zone in vivo should be different from the neutral zone in vitro.

Adolescent↗

Biomechanical role of the posterior elements, costovertebral joints, and rib cage in the stability of the thoracic spine.

STUDY DESIGN: This is a biomechanical study of the thoracic spine. Various ligaments and joints were resected sequentially and nondestructive cyclic loading tests were performed. Effects of each resection were analyzed biomechanically. OBJECTIVES: To investigate the role of the posterior elements, costovertebral joints, and rib cage in the stability of the thoracic spine. SUMMARY OF BACKGROUND DATA: There have been no experimental studies concerning the mechanical interaction between the thoracic spine and rib cage. METHODS: Eight canine rib cage-thoracic spine complexes, consisting of the sixth to eighth ribs, sternum, and T5-T9 vertebrae, were used. Six pure moments along three axes were applied to the specimens, and angular deformation of T6-T7 was recorded. After testing the intact specimen, resection of the stabilizers was conducted incrementally in the following manner: 1) removal of the posterior elements at T6-T7, 2) resection of the bilateral seventh costovertebral joints, and finally, 3) destruction of the rib cage. The same loading tests were repeated at each stage. The ranges of motion and neutral zones were calculated by digitization. RESULTS: A large increase in the range of motion in flexion-extension was observed after resection of the posterior elements and in lateral bending and axial rotation after resection of the costovertebral joints. A significant increase in the neutral zone in lateral bending and axial rotation was observed after bilateral resection of the costovertebral joints and destruction of the rib cage. CONCLUSIONS: The costovertebral joints and rib cage play an important role in providing stability to the thoracic spine. The state of the costovertebral joints and rib cage should be assessed to evaluate the stability of the thoracic spine.

Animals↗

New anterior instrumentation for the management of thoracolumbar and lumbar scoliosis. Application of the Kaneda two-rod system.

STUDY DESIGN: The Kaneda multisegmental instrumentation is a new anterior two-rod system for the correction of thoracolumbar and lumbar spine deformities. This system consists of a vertebral plate and two vertebral screws for individual vertebral bodies and two semirigid rods to interconnect the vertebral screws. Clinical results of 25 thoracolumbar and lumbar scoliosis patients treated with this new instrumentation were analyzed. OBJECTIVES: To evaluate the efficacy of the new anterior instrumentation in correction and stabilization of thoracolumbar and lumbar scoliosis. SUMMARY OF BACKGROUND DATA: Since Dwyer first introduced the concept of anterior spinal instrumentation and fusion for scoliosis, anterior surgery has gradually gained acceptance. In 1976, a useful modification for the anterior spinal instrumentation, which reportedly provided means of lordosation and vertebral body derotation, was described. However, some authors reported a high tendency of the implant breakage, loss of correction, progression of the kyphosis, and pseudoarthrosis as the major complications. To overcome the disadvantages of Zielke instrumentation, the authors have developed a new anterior spinal instrumentation (two-rod system) for the management of thoracolumbar and lumbar scoliosis. METHODS: Anterior correction and fusion using Kaneda multisegmental instrumentation was performed in 25 patients with thoracolumbar or lumbar scoliosis. The average follow-up period was 3 years, 1 month (range, 2 years to 4 years, 7 months). There were 20 patients with idiopathic scoliosis (13 adolescents and seven adults) and five patients with other types of scoliosis, including congenital and other etiologies. All patients had correction of scoliosis by fusion within the major curve, and for 16 of the 25 patients, the most distal end vertebra was not included in the fusion (short fusion). Radiographic evaluations were performed to analyze frontal and sagittal alignments of the spine. RESULTS: The average correction rate of scoliosis was 83%. Over the instrumented levels, the correction rate was 90%. Preoperative kyphosis of the instrumented levels of 7 degrees was corrected to 9 degrees of lordosis. Sagittal lordosis of the lumbosacral area beneath the fused segments averaged 51 degrees before surgery and was reduced to 34 degrees after surgery. The trunk shift was improved from 25 mm before surgery to 4 mm at final follow-up evaluation. The average improvement in the lower end vertebra tilt-angle was 97% in those patients whose lower end vertebra was included in the fusion and 83% in patients whose lower end vertebra was not included in the fusion. Apical vertebral rotation showed an average correction rate of 86%. At final follow-up evaluation, all patients demonstrated solid fusion without implant-related complications. There was 1.5 degrees of frontal plane and 1.5 degrees of sagittal plane correction loss within the instrumented area at final follow-up evaluation. CONCLUSIONS: New anterior two-rod system showed excellent correction of the frontal curvature and sagittal alignment with extremely high correction capability of rotational deformities. Furthermore, correction of thoracolumbar kyphosis to physiologic lordosis was achieved. This system provides flexibility of the implant for smooth application to the deformed spine and overall rigidity to correct the deformity and maintain the fixation without a significant loss of correction or implant failure compared with conventional one-rod instrumentation systems in anterior scoliosis correction.

Adolescent↗

Effects of degeneration on the elastic modulus distribution in the lumbar intervertebral disc.

STUDY DESIGN: Local elastic moduli of sliced intervertebral disc specimens were studied after establishing the relation between the elastic modulus and indentation behaviors by model tests using polyurethane specimens. OBJECTIVES: This study presents a method to quantify the distribution of compressive elastic moduli in the lumbar intervertebral disc and to clarify the effects of degeneration on the distribution. SUMMARY OF BACKGROUND DATA: No study has been performed to evaluate the distribution of axial compressive elastic moduli, which is supposed to relate previous biomechanical, biological, and biochemical findings regarding the intervertebral disc. METHODS: Local compressive elastic moduli of the intervertebral disc were estimated by indentation tests. To evaluate the distribution of elastic moduli, indentation tests were performed at nodal points of a 10 mm x 10 mm network on a specimen. Nine cadaveric lumbar discs (L3-L4 and L4-L5) with various degrees of degeneration were tested. The age of subjects ranged 39 to 90 years (mean, 58.4 years). RESULTS: The distribution of elastic moduli in normal discs was symmetric about the midsagittal plane. The mean elastic modulus in the nucleus pulposus was 5.8 kPa and those of the anterior and posterior anulus fibrosus were 110.7 and 75.8 kPa, respectively. The elastic moduli in the lateral portions were the lowest in the normal anulus, and were close to the values of the nucleus. Compared to normal discs, degenerated discs showed irregular distributions of elastic moduli. The elastic moduli of the degenerated nucleus were higher than those in normal discs. CONCLUSIONS: The distribution of elastic moduli is much different between discs with and without degeneration.

Adult↗

Migration of an acupuncture needle into the medulla oblongata.

A case of a delayed lesion of the medulla oblongata caused by migration of an acupuncture needle is presented. The patient was a 60-year-old woman who had undergone embedded-type acupuncture needle treatment around 1975. In 1993 she was admitted to our hospital with a 3-week history of progressive motor and sensory disturbance of her right upper extremity. CT demonstrated that one needle had penetrated the medulla oblongata transversely at the level of the foramen magnum. The needle was removed surgically without any complications. This is the first report of an acupuncture needle migrating in the medulla oblongata.

Acupuncture Therapy↗