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K Altman

Publications and source records attributed to K Altman.

45 records · Page 3Linked to original sources
PubMed1972

Hydrocortisone induction of rat-liver leucyl-transfer RNA and its synthetases.

Within 3 hr after the intraperitoneal administration of hydrocortisone to female rats, a new leucine-accepting tRNA and a new leucyl-tRNA synthetase activity appear in the liver cytosol. The new isoaccepting tRNA can be acylated only with the synthetase derived from livers of hormone-treated animals. Both components are transient; by 12 hr after hydrocortisone administration, the isoaccepting tRNA and its synthetase disappear from livers of treated animals.

Amino Acyl-tRNA Synthetases↗
PubMed1966

Tryptophan pyrrolase induced in human liver by hydrocortisone: effect on excretion of kynurenine.

Administration of hydrocortisone causes two- to fourfold increase in the level of activity of tryptophan pyrrolase in human liver, as measured in needle-biopsy specimens. Correlation of the higher levels of the enzyme with the amounts of urinary kynurenine suggests that the tryptophan pyrrolase level, which is regulated by adrenocortical hormones, may be the important variable in the increased excretion of tryptophan metabolites that accompanies various diseases.

Adult↗