The morphological study of lymph node biopsies by light and electron microscopes is reported. The patient was a 7 months old infant with Gaucher's disease and infection symptoms of upper respiratory ducts. We believe this to be a case of lesser affection, since the patient was admitted complaining of complications that gave way to medical treatment. Lymphadenopathy and moderate liver and splenomegaly were occasional findings during examination. Through the light microscope, Gaucher's cells showed an eccentric nucleous, cytoplasmic striae which, at the electron microscope showed to be tubular bodies.

Female↗

PubMedDate not supplied

[Perforation of the stomach in childhood].

Four cases of gastric perforation are studied in three male newborns and in a 14-year-old female out of 1949 autopsies performed from 1969 to 1978 at the Pathology Department of Hospital Infantil de México. All four cases showed clinical signs of respiratory failure and anatomical pulmonary lesions; this last feature led in all cases to hypoxia. Based on these data and on the opinion of several authors, hypoxia is believed to be the most important datum in the pathogenesis of gastric perforation in childhood.

Adolescent↗

PubMedDate not supplied

[Cholecystitis and cholecystolithiasis in children].

The study included 1880 necropsies and 8,217 biopsies and surgical pieces seen at the Pathology Department of the Hospital Infantil de México from 1968 to 1977. Among necropsies, two cases (0.10%) of cholecystitis and/or cholecystolithiasis were found and among surgical pieces there were seven (0.08%). Seven cases were females and two males. The symptoms most frequently found were: abdominal pain, jaundice, vomiting and leukocytosis. Morphologically, there were three cases of chronic cholecystitis with cholecystolithiasis, two cases of acute cholecystitis without calculi, two cases of chronic cholecystitis without calculi, one case of acute and chronic cholecystitis without calculi and another one cholecystolithiasis without inflammatory manifestations of the gallbladder. As etiological or predisposing factors we found: obesity, infections, parasitosis, hematologic disturbances, dilatation of the choledochus and one case with diaphragm of the 4th portion of the duodenum.

Adolescent↗

PubMedDate not supplied

[Ultrastructure of the hepatocyte during hepatic regeneration after partial hepatectomy].

A batch of 45 male Wistar rats, weighing 180 to 325 grams, were used in the experiment. Partial hepatectomy was practiced to them and liver biopsies taken at different periods of times: 0 (control) 4, 8, 12, 24, 36, 48, and 72 hours and 45 days. The biopsies were examined at the electron microscope. During liver regeneration, a sequence of morphological changes was detected, having started with an important decrease of cytoplasmic particles, increase of lipids and laminar bodies like myelin. After 24 hours, preparatory changes for cellular regeneration were observed prior to full regeneration which was reached later.

Animals↗

PubMedDate not supplied

[Idiopathic membranous glomerulonephritis].

The only case of idiopathic membranous glomerulonephritis seen out of 106 nephropathic patients biopsied in the two last years at the C. H. 20 de Noviembre, I.S.S.S.T.E., is reported. Twenty-six showed nephrotic syndrome not associated to systemic disease, including the present case, which gave us an incidence of 3.8% of this entity. We were impressed by the low frequency of this disease, so we made a statistical epidemiological analysis localizing it geographically based on the available medical literature. On comparing the results of these studies we confirmed that this disease is significantly low in our environment.

Basement Membrane↗

PubMedDate not supplied

[Ultrastructure of the human myocardium in inactive rheumatic fever].

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Biopsy↗