Biomedical subjects
Publications and source records attributed to K Ames.
A growing number of infertile women are being implanted with embryos conceived from their husband's sperm and eggs donated by other women. Though some clinics report a success rate of one in three, such adopt-an-embryo procedures pose legal, ethical and emotional problems.
When dying is all that awaits them, more and more people are choosing certain death now rather than uncertain life on medical support systems. But the decision seldom comes easy, as a Newsweek reporter discovers during three weeks with the doctors, nurses, patients and families in an intensive-care ward. A best-selling guide to suicide fires debate over when it is right to let life go--and who should make that choice when the patient no longer can.
In this study, 23 subjects wore a rigid extended wear (EW) lens overnight with a light pressure patch covering the eye while 19 subjects wore the same type of lens without patching. Corneal thickness measurements taken immediately upon awakening showed no significant difference in corneal swelling between the two groups. This result indicates that light pressure patching does not significantly affect the overnight corneal swelling found with rigid EW lenses, and it suggests that lagophthalmos during contact lens wear does not contribute significantly to the oxygen reaching the cornea during the closed-eye phase of overnight swelling studies.
The objective of our experiment was to examine changes in serum concentrations of estradiol in each utero-ovarian vein before, during and after gonadotropin surges. Four cows were given prostaglandin F2 alpha (PGF2 alpha) during diestrus and three cows were allowed to cycle spontaneously. All cows had a cannula in each utero-ovarian vein and in one jugular vein. Most cows had two transient rises in estradiol, primarily coming from a single ovary, preceding and after luteinizing hormone (LH) surges. The first rise in estradiol began after luteal regression and was sustained from 48 h before a pre-ovulatory LH surge to the end of the LH surge. The second rise in estradiol was sustained from 72 to 168 h after the end of an LH surge. To determine how rapidly asymmetrical production of estradiol began during luteolysis, several cows were injected with PGF2 alpha during the luteal phase. Blood samples were taken from a jugular and both utero-ovarian veins at hourly intervals before and after PGF2 alpha. Asymmetrical production of estradiol began within 3 h after an injection of PGF2 alpha. We concluded: (1) that a single ovary was responsible for the sustained increases in concentration of estradiol that occur during proestrus to estrus and early diestrus in cows and (2) that cows may have at least one follicle capable of producing estradiol during most days of an estrous cycle, thus little delay in selection of which follicle eventually ovulates occurs after luteal regression.
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